六氢-4-[3-[2-(三氟甲基)-10H-吩噻嗪-10-基]丙基]-1H-1,4-二氮杂卓-1-乙醇二盐酸盐

  • 基本信息
  • 物化性质
  • 毒理性

六氢-4-[3-[2-(三氟甲基)-10H-吩噻嗪-10-基]丙基]-1H-1,4-二氮杂卓-1-乙醇二盐酸盐 基本信息

中文名称:
六氢-4-[3-[2-(三氟甲基)-10H-吩噻嗪-10-基]丙基]-1H-1,4-二氮杂卓-1-乙醇二盐酸盐 
中文别名:
1H-1,4-Diazepine-1-ethanol,hexahydro-4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-,hydrochloride (1:2) 
英文名称:
1H-1,4-Diazepine-1-ethanol,hexahydro-4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-,hydrochloride (1:2)
英文别名:
1H-1,4-Diazepine-1-ethanol,hexahydro-4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-,hydrochloride (1:2);
Homofenazin dihydrochloride;
Homophenazine;
Oldagen;
Homofenazine dihydrochloride;
Homophenazine dihydrochloride;
Homofenazin-dihydrochlorid 
CAS No.:
1256-01-5
分 子 式:
C23H28F3N3OS.2ClH
分 子 量:
524.4700096
精确分子量:
487.16700
PSA:
55.25000
InChI:
The Key: JQOGQVPDLQTZQC-UHFFFAOYSA-N
分子结构式:
SDS:
查看

六氢-4-[3-[2-(三氟甲基)-10H-吩噻嗪-10-基]丙基]-1H-1,4-二氮杂卓-1-乙醇二盐酸盐 物化性质

沸点:
574ºC at 760 mmHg
闪点:
301ºC
蒸汽压:
5.12E-14mmHg at 25°C

六氢-4-[3-[2-(三氟甲基)-10H-吩噻嗪-10-基]丙基]-1H-1,4-二氮杂卓-1-乙醇二盐酸盐 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HM4025000
CHEMICAL NAME :
1H-1,4-Diazepine, hexahydro-1-(2-hydroxyethyl)-4-(3-((2-trifluoromethyl phenothiazinyl)- 10)-propyl)-, dihydrochloride
CAS REGISTRY NUMBER :
1256-01-5
LAST UPDATED :
199012
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C23-H28-F3-N3-O-S.2Cl-H
MOLECULAR WEIGHT :
524.52
WISWESSER LINE NOTATION :
T C666 BN ISJ FXFFF B3- AT7N DNTJ D2Q &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
880 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,25,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
166 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,25,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
102 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,25,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
790 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,25,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
138 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,25,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
960 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,25,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
73500 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,25,1972

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