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- 2,4-二(氮丙啶-1-基)-6-氯嘧啶
2,4-二(氮丙啶-1-基)-6-氯嘧啶 基本信息
- 中文名称：
- 2,4-二(氮丙啶-1-基)-6-氯嘧啶
- 中文别名：
-
- 英文名称：
- Pyrimidine,2,4-bis(1-aziridinyl)-6-chloro-
- 英文别名：
- 2,4-bis(aziridin-1-yl)-6-chloropyrimidine;
2,4-Bis-aziridin-1-yl-6-chlor-pyrimidin;
Ethymidine;
Aethimidinum;
2,4-Diethylenimino-6-chloropyrimidine;
2,4-bis-aziridin-1-yl-6-chloro-pyrimidine;
Etimidin;
Ethimidine;
2,6-Diethylenimino-4-chloropyrimidine;
Aethimidinium
- CAS No.：
- 2482-80-6
- 分 子 式：
- C8H9ClN4
- 分 子 量：
- 196.66
- 精确分子量：
- 196.05200
- PSA：
- 31.80000
- InChI：
- The Key: CUINYHNUVZSCAS-UHFFFAOYSA-N
- 安全术语：
- Poison by intravenous route. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx and Cl−.
- 分子结构式：
-
- SDS：
- 查看
2,4-二(氮丙啶-1-基)-6-氯嘧啶 物化性质
- 密度：
- 1.561g/cm3
- 沸点：
- 410.4ºC at 760mmHg
- 闪点：
- 202ºC
- 折射率：
- 1.711
- 蒸汽压：
- 6.06E-07mmHg at 25°C
2,4-二(氮丙啶-1-基)-6-氯嘧啶 安全信息
2,4-二(氮丙啶-1-基)-6-氯嘧啶 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UV7065000
- CHEMICAL NAME :
- Pyrimidine, 2,4-bis(1-aziridinyl)-6-chloro-
- CAS REGISTRY NUMBER :
- 2482-80-6
- BEILSTEIN REFERENCE NO. :
- 0188373
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C8-H9-Cl-N4
- MOLECULAR WEIGHT :
- 196.66
- WISWESSER LINE NOTATION :
- T6N CNJ DG B- AT3NTJ& F- AT3NTJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 15 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Ear) - change in acuity
Gastrointestinal - nausea or vomiting
Tumorigenic - active as anti-cancer agent
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 15 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Ear) - change in acuity
Gastrointestinal - nausea or vomiting
Tumorigenic - active as anti-cancer agent
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 15 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay)
Behavioral - muscle contraction or spasticity
Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1350 ug/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay)
Behavioral - muscle contraction or spasticity
Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
MUTATION DATA
- TEST SYSTEM :
- Rodent - rat
- DOSE/DURATION :
- 2500 ug/kg
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 6,357,1951
2,4-二(氮丙啶-1-基)-6-氯嘧啶 海关数据
中国海关编码：2933990090
- 概述：
- 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
- 摘要/Summary：
- 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
