硼酸

  • 基本信息
  • 制备方法及用途
  • 物化性质
  • 安全信息
  • 毒理性
  • MSDS
  • 结构与计算化学
  • 表征图谱

硼酸 基本信息

中文名称:
硼酸 
中文别名:
硼酸;
硼的,含硼的;
硼酸(医药级);
硼酸(电容器级);
硼酸,5N;
正硼酸;
原硼酸;
工业硼酸 
英文名称:
Orthoboric acid
英文别名:
boric acid;
Borsaure;
Borsure;
sassoline BH3O3,sassolite;
TBE BUFFER;
Boric acid,DNAse,RNAse and Protease free;
Borofax;
boric;
Boracic;
fleaprufe 
CAS No.:
10043-35-3
分 子 式:
BH3O3
分 子 量:
61.83
精确分子量:
62.01750
PSA:
60.69000
MDL:
MFCD00011337
EINECS:
233-139-2
BRN:
1697939
InChI:
The Key: KGBXLFKZBHKPEV-UHFFFAOYSA-N
危险品标志:
toxict;irritantxi
风险术语:
R60;
安全术语:
S45; S53;
分子结构式:
SDS:
查看

硼酸 制备方法及用途

合成制备方法

1.硼砂硫酸中和法

用途

1.大量用于玻璃(光学玻璃、耐酸玻璃、耐热玻璃、绝缘材料用玻璃纤维)工业,可以改善玻璃制品的耐热、透明性能,提高机械强度,缩短熔融时间。在搪瓷、陶瓷业中,用以增强搪瓷产品的光泽和坚牢度,也是釉药和颜料的成分之一。冶金工业中作添加剂、助溶剂,特别是硼钢具有高硬度和良好的轧延性,可以代替镍钢。硼酸有防腐性,可作防腐剂,如木材防腐。在金属焊接、皮革、照相等行业以及染料、耐热防火织物、人造宝石、电容器、化妆品的制造方面都用到它。还可作杀虫剂和催化剂用。农业上含硼微量元素肥料,对许多作物有肥效,能增进作物品质和提高产量。硼酸也是生产其他硼化物的基本原料之一,由它生产的硼化合物广泛应用于国防及其他工业部门和科研单位。

2.用于皮肤病、消毒防腐。

3.分析中用于配制缓冲溶液,如硼酸,氯化钾  氢氧化钠缓冲溶液,酸钠缓冲溶液。还用作杀菌剂。用于制药及制备硼酸盐。

4.用于制造电容器,消毒、防腐。

5.用于电子工业,光纤工业。

6.用作淀粉、聚乙烯酸和聚乙烯酸缩甲醛等水溶性胶黏剂的增黏剂或交联剂。也可用作防腐、防毒剂。硼酸是生产硼化物及硼酸盐的基本原料,大量用于玻璃工业生产光学玻璃、耐酸玻璃、有机硼玻璃等高级玻璃及玻璃纤维。在陶瓷、搪瓷工业上用于生产釉药。冶金工业中用作添加剂、助熔剂。医药工业用于生产消毒剂、收敛剂、防腐剂及硼酸软膏等。印染工业中用作织物防火整理剂。皮革工业中用于裸皮表面脱灰。化妆品工业用于生产硼酸药皂及酸碱度调节剂。还可用作木材防腐剂、杀虫剂、催化剂、防霉剂,以及配制缓冲液,用于电子、稀有金属冶炼、照相、人造宝石等行业。

硼酸 物化性质

外观与性状:
无色或白色无臭结晶固体
密度:
1.435
熔点:
169 °C
沸点:
219-220 °C (9.7513 mmHg)
水溶解性:
49.5 g/L (20 ºC)
折射率:
1.385
存储条件/存储方法:
库房通风低温干燥,与金属钾分开存放,与(CH3CO)2O分开存放
稳定性相关:

1.实际上是氧化硼的水合物,为白色粉末状结晶或三斜轴面的鳞片状带光泽结晶。有滑腻手感,无臭味。无气味。味微酸苦后带甜。与皮肤接触有滑腻感。露置空气中无变化。能随水蒸气挥发。加热至100~105℃时失去一分子水而形成偏硼酸,于104~160℃时长时间加热转变为焦硼酸,更高温度则形成无水物。0.1mol/L水溶液的pH为5.1。
其它信息:

 1.       性状:为白色粉末状结晶或三斜轴面的鳞片状带光泽结晶。

2.       密度(g/mL,25/4℃):1.435

硼酸 安全信息

海关代码:
2810002000
WGK_Germany:
2
德国有关水污染物质的分类清单
危险类别码:
R60
安全说明:
S26-S36-S53-S45
RTECS号:
ED4550000
危险标志:
T:Toxic;

硼酸 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ED4550000
CHEMICAL NAME :
Boric acid
CAS REGISTRY NUMBER :
10043-35-3
LAST UPDATED :
199712
DATA ITEMS CITED :
62
MOLECULAR FORMULA :
B-H3-O3
MOLECULAR WEIGHT :
61.84
WISWESSER LINE NOTATION :
QBQQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Human
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
429 mg/kg
TOXIC EFFECTS :
Cardiac - other changes Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - child
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Gastrointestinal - nausea or vomiting
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - woman
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Behavioral - fluid intake Gastrointestinal - hypermotility, diarrhea Gastrointestinal - nausea or vomiting
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - infant
DOSE/DURATION :
800 mg/kg/4W-I
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Gastrointestinal - hypermotility, diarrhea Gastrointestinal - nausea or vomiting
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - infant
DOSE/DURATION :
934 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Human - infant
DOSE/DURATION :
1200 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Skin and Appendages - dermatitis, other (after systemic exposure) Nutritional and Gross Metabolic - body temperature increase
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Human - child
DOSE/DURATION :
4 gm/kg/4D
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
2430 mg/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea Skin and Appendages - primary irritation (after topical exposure) Nutritional and Gross Metabolic - body temperature increase
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Human - child
DOSE/DURATION :
1500 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - conjunctive irritation Lungs, Thorax, or Respiration - respiratory depression Gastrointestinal - hypermotility, diarrhea
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Human - infant
DOSE/DURATION :
1100 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Gastrointestinal - hypermotility, diarrhea Gastrointestinal - nausea or vomiting
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
170 mg/kg
TOXIC EFFECTS :
Behavioral - wakefulness Behavioral - anorexia (human) Gastrointestinal - nausea or vomiting
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
147 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2660 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
28 mg/m3/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1400 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Nutritional and Gross Metabolic - body temperature decrease
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1330 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Gastrointestinal - hypermotility, diarrhea Gastrointestinal - nausea or vomiting
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3450 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Nutritional and Gross Metabolic - body temperature decrease
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1740 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1240 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression Gastrointestinal - hypermotility, diarrhea
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
1780 mg/kg
TOXIC EFFECTS :
Brain and Coverings - meningeal changes Lungs, Thorax, or Respiration - cyanosis Gastrointestinal - nausea or vomiting
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Brain and Coverings - meningeal changes Lungs, Thorax, or Respiration - cyanosis Gastrointestinal - nausea or vomiting
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Parenteral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage)
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
4 gm/kg
TOXIC EFFECTS :
Behavioral - tremor Gastrointestinal - hypermotility, diarrhea Gastrointestinal - nausea or vomiting
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Nutritional and Gross Metabolic - body temperature decrease
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Parenteral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
670 mg/kg
TOXIC EFFECTS :
Nutritional and Gross Metabolic - body temperature decrease
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Gastrointestinal - nausea or vomiting Gastrointestinal - other changes
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
1200 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Gastrointestinal - hypermotility, diarrhea Gastrointestinal - nausea or vomiting
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
45 gm/kg/90D-C
TOXIC EFFECTS :
Brain and Coverings - changes in brain weight Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - changes in testicular weight
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
68 mg/kg/9W-I
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain Nutritional and Gross Metabolic - changes in calcium Nutritional and Gross Metabolic - changes in phosphorus
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
42 gm/kg/14D-C
TOXIC EFFECTS :
Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
156 gm/kg/13W-I
TOXIC EFFECTS :
Gastrointestinal - other changes Blood - changes in spleen Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
23 gm/kg/90D-C
TOXIC EFFECTS :
Liver - changes in liver weight Endocrine - changes in thyroid weight Related to Chronic Data - changes in testicular weight
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
6600 mg/kg
SEX/DURATION :
female 1-21 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
45 gm/kg
SEX/DURATION :
male 90 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - testes, epididymis, sperm duct
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
5390 mg/kg
SEX/DURATION :
female 6-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Specific Developmental Abnormalities - musculoskeletal system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
1596 mg/kg
SEX/DURATION :
female 0-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
52 mg/kg
SEX/DURATION :
male 26 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
DOSE :
9600 ug/m3/4H
SEX/DURATION :
male 16 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
7684 mg/kg
SEX/DURATION :
female 1-17 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
17051 mg/kg
SEX/DURATION :
female 1-17 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
18054 mg/kg
SEX/DURATION :
female 1-18 day(s) after conception
TOXIC EFFECTS :
Reproductive - Maternal Effects - uterus, cervix, vagina Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
8136 mg/kg
SEX/DURATION :
female 1-18 day(s) after conception
TOXIC EFFECTS :
Reproductive - Maternal Effects - other effects Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
3500 mg/kg
SEX/DURATION :
female 6-19 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
3500 mg/kg
SEX/DURATION :
female 6-19 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
3500 mg/kg
SEX/DURATION :
female 7-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
3500 mg/kg
SEX/DURATION :
female 6-19 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
1750 mg/kg
SEX/DURATION :
female 7-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Maternal Effects - uterus, cervix, vagina Reproductive - Maternal Effects - other effects

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
17000 ppm/24H
REFERENCE :
AMNTA4 American Naturalist. (Univ. of Chicago Press, Journals Div., POB 37005, Chicago, IL 60637) V.1- 1867- Volume(issue)/page/year: 85,119,1951 *** REVIEWS *** TOXICOLOGY REVIEW CLCHAU Clinical Chemistry (Winston-Salem, NC). (American Assoc. for Clinical Chemistry, 1725 K St., NW, Washington, DC 20006) V.1- 1955- Volume(issue)/page/year: 19,361,1973 TOXICOLOGY REVIEW FNSCA6 Forensic Science. (Lausanne, Switzerland) V.1-11, 1972-78. For pub lisher information, see FSINDR. Volume(issue)/page/year: 2,67,1973 TOXICOLOGY REVIEW JOPDAB Journal of Pediatrics. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1932- Volume(issue)/page/year: 61,531,1962 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 10 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7080 No. of Facilities: 27071 (estimated) No. of Industries: 187 No. of Occupations: 128 No. of Employees: 489668 (estimated) No. of Female Employees: 211838 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X8324 No. of Facilities: 84 (estimated) No. of Industries: 3 No. of Occupations: 4 No. of Employees: 2919 (estimated) No. of Female Employees: 1712 (estimated)
毒理学数据:

大鼠经口LD50: 5.14g/kg。人经皮:15mg/3天,出现间歇染毒,中度刺激。硼酸可引起皮肤刺激、结膜炎、支气管炎。

生态数据:

通常对水体是稍微有害的,不要将未稀释或大量产品接触地下水,水道或污水系统,未经政府许可勿将材料排入周围环境。

硼酸 MSDS

第一部分:化学品名称
化学品中文名称: 硼酸
化学品英文名称: boric acid
中文俗名或商品名:  
Synonyms:  
CAS No.: 10043-35-3
分子式: 无资料
分子量: 无资料
第二部分:成分/组成信息
             纯化学品   混合物
             化学品名称:硼酸
有害物成分 含量 CAS No.
硼酸 100 10043-35-3
第三部分:危险性概述
危险性类别:  
侵入途径: 工业生产中,仅见引起皮肤刺激、结膜炎、支气管炎,一般无中毒发生。口服引起急性中毒,主要表现为胃肠道症状,有恶心、呕吐、腹痛、腹泻等,继之发生脱水、休克、昏迷或急性肾功能衰竭,可有高热、肝肾损害和惊厥,重者可致死。皮肤出现广泛鲜红色疹,重者成剥脱性皮炎。本品易被损伤皮肤吸收引起中毒。慢性中毒:长期由胃肠道或皮肤吸收小量该品,可发生轻度消化道症状、皮炎、秃发以及肝肾损害。
健康危害: 无资料
环境危害: 无资料
燃爆危险: 本品不燃,具刺激性。
第四部分:急救措施
皮肤接触: 脱去污染的衣着,用大量流动清水冲洗。就医。
眼睛接触: 提起眼睑,用流动清水或生理盐水冲洗。就医。
吸入: 脱离现场至空气新鲜处。如呼吸困难,给输氧。就医。
食入: 饮足量温水,催吐。洗胃,导泄。就医。
第五部分:消防措施
危险特性: 受高热分解放出有毒的气体。
有害燃烧产物: 氧化硼
灭火方法及灭火剂: 消防人员必须穿全身防火防毒服,在上风向灭火。灭火时尽可能将容器从火场移至空旷处。
消防员的个体防护: 无资料
禁止使用的灭火剂: 无资料
闪点(℃): 无资料
自燃温度(℃): 无资料
爆炸下限[%(V/V)]: 无资料
爆炸上限[%(V/V)]: 无资料
最小点火能(mJ):  
爆燃点:  
爆速:  
最大燃爆压力(MPa):  
建规火险分级:  
第六部分:泄漏应急处理
应急处理: 隔离泄漏污染区,限制出入。建议应急处理人员戴防尘面具(全面罩),穿防毒服。用砂土、干燥石灰或苏打灰混合。小心扫起,转移至安全场所。若大量泄漏,用塑料布、帆布覆盖。收集回收或运至废物处理场所处置。
第七部分:操作处置与储存
操作注意事项: 密闭操作,加强通风。操作人员必须经过专门培训,严格遵守操作规程。建议操作人员佩戴自吸过滤式防尘口罩,戴化学安全防护眼镜,穿防毒物渗透工作服,戴橡胶手套。避免产生粉尘。避免与碱类、钾接触。搬运时轻装轻卸,保持包装完整,防止洒漏。配备泄漏应急处理设备。倒空的容器可能残留有害物。
储存注意事项: 储存于阴凉、通风的库房。远离火种、热源。应与碱类、钾分开存放,切忌混储。储区应备有合适的材料收容泄漏物。
第八部分:接触控制/个体防护
最高容许浓度: 前苏联MAC(mg/m3): 10
监测方法: 无资料
工程控制: 生产过程密闭,加强通风。
呼吸系统防护: 空气中粉尘浓度超标时,必须佩戴自吸过滤式防尘口罩。紧急事态抢救或撤离时,应该佩戴空气呼吸器。
眼睛防护: 戴化学安全防护眼镜。
身体防护: 穿防毒物渗透工作服
手防护: 戴橡胶手套。
其他防护: 工作完毕,淋浴更衣。保持良好的卫生习惯
第九部分:理化特性
外观与性状: 无色微带珍珠光泽的三斜晶体或白色粉末,有滑腻手感, 无臭味。
pH:  
熔点(℃): 185(分解)
沸点(℃): 300
相对密度(水=1): 1.44(15℃)
相对蒸气密度(空气=1): 无资料
饱和蒸气压(kPa):  
燃烧热(kJ/mol):  
临界温度(℃):  
临界压力(MPa):  
辛醇/水分配系数的对数值:  
闪点(℃): 无资料
引燃温度(℃): 无资料
爆炸上限%(V/V): 无资料
爆炸下限%(V/V): 无资料
分子式: 无资料
分子量: 无资料
蒸发速率:  
粘性:  
溶解性: 溶于水,溶于乙醇、乙醚、甘油。
主要用途: 用于玻璃、搪瓷、医药、化妆品等工业, 以及制备硼和硼酸盐, 并用作食物防腐剂和消毒剂等。
第十部分:稳定性和反应活性
稳定性: 在常温常压下
禁配物: 碱类、钾。
避免接触的条件: 无资料
聚合危害: 无资料
分解产物: 无资料
第十一部分:毒理学资料
急性毒性: 无资料
急性中毒: 无资料
慢性中毒: 无资料
亚急性和慢性毒性:  
刺激性: 人经皮:15mg/3天,间歇染毒,中度刺激。
致敏性:  
致突变性:  
致畸性:  
致癌性:  
第十二部分:生态学资料
生态毒理毒性: 无资料
生物降解性: 无资料
非生物降解性: 无资料
生物富集或生物积累性:  
第十三部分:废弃处置
废弃物性质: 无资料
废弃处置方法: 根据国家和地方有关法规的要求处置。或与厂商或制造商联系,确定处置方法。
废弃注意事项: 无资料
第十四部分:运输信息
 
 
危险货物编号: 无资料
UN编号: 无资料
包装标志:  
包装类别:  
包装方法: 无资料
运输注意事项: 起运时包装要完整,装载应稳妥。运输过程中要确保容器不泄漏、不倒塌、不坠落、不损坏。严禁与碱类、钾、食用化学品等混装混运。运输途中应防曝晒、雨淋,防高温。车辆运输完毕应进行彻底清扫。
RETCS号:  
IMDG规则页码:  
第十五部分:法规信息
国内化学品安全管理法规: 化学危险物品安全管理条例 (1987年2月17日国务院发布),化学危险物品安全管理条例实施细则 (化劳发[1992] 677号),工作场所安全使用化学品规定 ([1996]劳部发423号)等法规,针对化学危险品的安全使用、生产、储存、运输、装卸等方面均作了相应规定
国际化学品安全管理法规:  
第十六部分:其他信息
参考文献:  
填表时间: 2005年1月13日
填表部门: 无资料
数据审核单位: 无资料
修改说明: 无资料
其他信息:  
MSDS修改日期: 1900年1月1日

硼酸 分子结构与计算化学数据

分子结构数据

1、摩尔折射率:10.08

2、摩尔体积(cm3/mol):43

3、等张比容(90.2K):119.2

4、表面张力(dyne/cm):59.1

5、介电常数:无可用的

6、极化率(10-24cm3):3.99

7、单一同位素质量:62.017525 Da

8、标称质量:62 Da

9、平均质量:61.833 Da

计算化学数据

1.疏水参数计算参考值(XlogP):无

2.氢键供体数量:3

3.氢键受体数量:3

4.可旋转化学键数量:0

5.互变异构体数量:无

6.拓扑分子极性表面积60.7

7.重原子数量:4

8.表面电荷:0

9.复杂度:8

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

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