霉酚酸钠

基本信息
物化性质
毒理性

霉酚酸钠基本信息

中文名称：: 霉酚酸钠

中文别名：: 霉酚酸钠;
吗替麦考酚钠

英文名称：: 4-Hexenoic acid,6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-,sodium salt (1:1), (4E)-

英文别名：: mycophenolate sodium;
mycophenolicmonosodiumsalt;
MYCOPHENOLATE SODIUM;
Mycophenolic acid monosodium salt;
sodiummycophenolate;
mycophenolicacidmonosodiumsalt

CAS No.：: 37415-62-6

分子式：: C₁₇H₂₀O₆.Na

分子量：: 342.35

精确分子量：: 343.11600

PSA：: 93.06000

安全术语：: Poison by intravenous route. Moderately toxic by ingestion and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits toxic fumes of Na2O.

分子结构式：

SDS：: 查看

霉酚酸钠物化性质

密度：: 1.29 g/cm3
沸点：: 611.6ºC at 760 mmHg
闪点：: 225.8ºC

霉酚酸钠毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MP8100000

CHEMICAL NAME :: 4-Hexenoic acid, 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4 -methyl-, sodium salt

CAS REGISTRY NUMBER :: 37415-62-6

LAST UPDATED :: 199606

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C17-H19-O6.Na

MOLECULAR WEIGHT :: 342.35

WISWESSER LINE NOTATION :: T56 BVO DHJ FQ G2UY1&2VO HO1 I1 &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1176 mg/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 568 mg/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Rodent - mouse Fibroblast

DOSE/DURATION :: 100 ug/L

REFERENCE :: BIJOAK Biochemical Journal. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1906- Volume(issue)/page/year: 113,515,1969 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83943 No. of Facilities: 33 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 99 (estimated)