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盐酸海洛因 基本信息
- 中文名称：
- 盐酸海洛因
- 中文别名：
- 盐酸海洛因
- 英文名称：
- Morphinan-3,6-diol,7,8-didehydro-4,5-epoxy-17-methyl- (5a,6a)-, diacetate (ester), hydrochloride
- 英文别名：
- [(4R,4aR,7S,7aR,12bS)-9-acetyloxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl] acetate,hydrochloride;
Diamorphine hydrochloride;
BAN hydrochloride;
Heroin hydrochloride solution;
Diacetylmorphinhydrochloridmonohydrat;
Diacetylmorphine HCl;
UNII-8H672SHT8E;
EINECS 216-124-5;
(-)-Heroin hydrochloride;
Acetomorphin hydrochloride;
diacetylmorphine hydrochloride;
Heroine hydrochloride
- CAS No.：
- 1502-95-0
- 分 子 式：
- C21H23NO5.ClH
- 分 子 量：
- 405.91
- 精确分子量：
- 405.13400
- PSA：
- 65.07000
- InChI：
- The Key: FZJYQGFGNHGSFX-PVQKIFDLSA-N
- 危险品标志：
- 风险术语：
- 11-23/24/25-39/23/24/25
- 安全术语：
- Poison by intraperitoneal and intravenous routes. An experimental teratogen. A narcotic. Addictive. When heated to decomposition it emits very toxic fumes of NOx and HCl. See also HEROIN and (−)-MORPHINE.
- 分子结构式：
-
- SDS：
- 查看
盐酸海洛因 物化性质
- 沸点：
- 492.9ºC at 760mmHg
- 闪点：
- 251.9ºC
- 蒸汽压：
- 7.38E-10mmHg at 25°C
- 存储条件/存储方法：
- 库房通风低温干燥,与氧化剂,食品分开储运
盐酸海洛因 安全信息
- 包装等级：
- II
- 风险类别：
- 6.1(a)
- 危险类别码：
- 11-23/24/25-39/23/24/25
- 危险标志：
- F: Flammable;T: Toxic;
盐酸海洛因 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QC8225000
- CHEMICAL NAME :
- Morphinan-3,6-alpha-diol,
7,8-didehydro-4,5-alpha-epoxy-17-methyl-, diacetate
(ester), hydrochloride
- CAS REGISTRY NUMBER :
- 1502-95-0
- LAST UPDATED :
- 199306
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C21-H23-N-O5.Cl-H
- MOLECULAR WEIGHT :
- 405.91
- WISWESSER LINE NOTATION :
- T B6566 B6/CO 4ABBC R BX HO PN DU GHT&&TTJ FOV1 JOV1
P1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 240 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 122,434,1959
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >60 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 221,266,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 38 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
6,334,1964
** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 80 mg/kg
- SEX/DURATION :
- female 9 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetal death
- REFERENCE :
- TJADAB Teratology, The International Journal of Abnormal Development. (Alan
R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968-
Volume(issue)/page/year: 31,235,1985
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 65 mg/kg
- SEX/DURATION :
- female 9 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - Central Nervous System
- REFERENCE :
- TJADAB Teratology, The International Journal of Abnormal Development. (Alan
R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968-
Volume(issue)/page/year: 31,235,1985
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 80 mg/kg
- SEX/DURATION :
- female 9 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetal death
Reproductive - Specific Developmental Abnormalities - Central Nervous System
- REFERENCE :
- DGDFA5 Development, Growth & Differentiation. (Japan Pub. Trading Co.
(USA), 1255 Howard St., San Francisco, CA 94103) V.11- 1969-
Volume(issue)/page/year: 22,61,1980
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 100 mg/kg
- SEX/DURATION :
- female 9-18 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - Central Nervous System
Reproductive - Effects on Newborn - behavioral
- REFERENCE :
- DBRRDB Developmental Brain Research. (Elsevier Science Pub. B.V., POB 211,
1000 AE Amsterdam, Netherlands) V.1- 1981- Volume(issue)/page/year:
69,207,1992
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 148 mg/kg
- SEX/DURATION :
- female 8 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - Central Nervous System
Reproductive - Specific Developmental Abnormalities - other developmental
abnormalities
- REFERENCE :
- AJOGAH American Journal of Obstetrics and Gynecology. (C.V. Mosby Co.,
11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1920-
Volume(issue)/page/year: 123,705,1975
