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基雅尼霉素 基本信息
- 中文名称：
- 基雅尼霉素
- 中文别名：
- From Actinomadura Kijaniata
- 英文名称：
- 18H-16a,19-Metheno-16aH-benzo[b]naphth[2,1-j]oxacyclotetradecin-18,20(1H)-dione,4-[(O-2,6-dideoxy-a-L-ribo-hexopyranosyl-(1®3)-O-[2,6-dideoxy-4-O-methyl-b-L-ribo-hexopyranosyl-(1®4)]-O-2,6-dideoxy-a-L-ribo-hexopyranosyl-(1®3)-2,6-dideoxy-a-L-ribo-hexopyranosyl)oxy]-2,3,4,4a,6a,9,10,12a,15,16,20a,20b-dodecahydro-21-hydroxy-14-(hydroxymethyl)-1,3,7,11,15,20a-hexamethyl-10-[[2,3,4,6-tetradeoxy-4-[(methoxycarbonyl)amino]-3-C-methyl-3-nitro-b-D-xylo-hexopyranosyl]oxy]-,(1S,3S,4S,4aS,6aS,7E,10S,11E,12
- 英文别名：
- From Actinomadura Kijaniata;
kijanimicin
- CAS No.：
- 78798-08-0
- 分 子 式：
- C67H100N2O24
- 分 子 量：
- 0
- 精确分子量：
- 1316.67000
- PSA：
- 350.43000
- InChI：
- The Key: AAHYWTFSLXCSNH-DYYADRANSA-N
- 分子结构式：
-
- SDS：
- 查看
基雅尼霉素 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- OB8650500
- CHEMICAL NAME :
- Kijanimicin
- CAS REGISTRY NUMBER :
- 78798-08-0
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C67-H100-N2-O24
- MOLECULAR WEIGHT :
- 1317.69
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 125 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - peritonitis
- REFERENCE :
- TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway,
Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 4,6,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EPXXDW European Patent Application. (U.S. Patent and Trademark Office,
Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #33840
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 170 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - peritonitis
- REFERENCE :
- TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway,
Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 4,6,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EPXXDW European Patent Application. (U.S. Patent and Trademark Office,
Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #33840
