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阿托品氧化物 基本信息
- 中文名称：
- 阿托品氧化物
- 中文别名：
- 8-Azabicyclo[3.2.1]octan-3.α.-ol, 8-methyl-, 8-oxide, tropate
- 英文名称：
- Benzeneacetic acid, a-(hydroxymethyl)-,8-methyl-8-oxido-8-azabicyclo[3.2.1]oct-3-yl ester, endo-
- 英文别名：
- 8-Azabicyclo[3.2.1]octan-3.α.-ol, 8-methyl-, 8-oxide, tropate;
DL-tropic acid-(8-oxy-tropane-3endo-yl ester);
DL-Tropasaeure-(8-oxy-tropan-3endo-ylester);
Genatropine;
atropine oxide;
Aminoxytropine tropate
- CAS No.：
- 4438-22-6
- 分 子 式：
- C17H23NO4
- 分 子 量：
- 0
- 精确分子量：
- 305.16300
- PSA：
- 75.96000
- InChI：
- The Key: HGWPFSBHDACWNL-LZYIFBDPSA-N
- 分子结构式：
-
- SDS：
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阿托品氧化物 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YM6105000
- CHEMICAL NAME :
- 1-alpha-H,5-alpha-H-Tropan-3-alpha-ol, (+-)-tropate
(ester), 8-oxide
- CAS REGISTRY NUMBER :
- 4438-22-6
- LAST UPDATED :
- 198708
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C17-H23-N-O4
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- RDMU** "Vergleichende Untersuchungen uber Genatropin und Atropin,
Dissertation," Rathscheck, U., Pharmakologischen Institut der Westfalichen
Wilhelms-Universitat Muenster/Westf., Fed. Rep. Ger., 1934
Volume(issue)/page/year: -,-,1934
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 225 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme
Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948
Volume(issue)/page/year: -,513,1948
