1,4-二(氯甲氧基甲基)苯

  • 基本信息
  • 物化性质
  • 毒理性

1,4-二(氯甲氧基甲基)苯 基本信息

中文名称:
1,4-二(氯甲氧基甲基)苯 
中文别名:
1,4-bis(chloromethoxymethyl)benzene 
英文名称:
Benzene,1,4-bis[(chloromethoxy)methyl]-
英文别名:
1,4-bis(chloromethoxymethyl)benzene;
BIS-1,4(CHLOROMETHOXY)-PARA-XYLENE 
CAS No.:
56894-91-8
分 子 式:
C10H12Cl2O2
分 子 量:
235.12
精确分子量:
234.02100
PSA:
18.46000
InChI:
The Key: BXIVHTWXKYBJEM-UHFFFAOYSA-N
安全术语:
Questionable carcinogen with experimental neoplastigenic and tumorigenic data. When heated to decomposition it emits toxic fumes of Cl−.
分子结构式:
SDS:
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1,4-二(氯甲氧基甲基)苯 物化性质

密度:
1.233g/cm3
沸点:
307.1ºC at 760 mmHg
闪点:
114.4ºC
折射率:
1.526
存储条件/存储方法:
库房通风低温干燥

1,4-二(氯甲氧基甲基)苯 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CY8420000
CHEMICAL NAME :
Benzene, 1,4-bis(chloromethoxymethyl)-
CAS REGISTRY NUMBER :
56894-91-8
LAST UPDATED :
199510
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C10-H12-Cl2-O2
MOLECULAR WEIGHT :
235.12
WISWESSER LINE NOTATION :
G1O1R D1O1G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2590 mg/kg/72W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,2553,1975
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
310 mg/kg/78W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,2553,1975
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
970 mg/kg/81W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,2553,1975 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,37,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,37,1977 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

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