• 基本信息
  • 物化性质
  • 毒理性

基本信息

中文名称:
 
中文别名:
 
英文名称:
Glycine,N,N-bis(2-chloroethyl)-, hydrochloride (6CI,7CI,8CI,9CI)
英文别名:
Glycine,N,N-bis(2-chloroethyl)-, hydrochloride (6CI,7CI,8CI,9CI);
N,N-Bis(2-chloraethyl)formamid;
N,N-Bis-(2-chlor-aethyl)-glycin,Hydrochlorid;
N,N-bis-(2-chloro-ethyl)formamide;
Ameisensaeure-[bis-(2-chlor-aethyl)-amid];
2--essigsaeure;
N,N-bis-(2-chloro-ethyl)-glycine,hydrochloride;
FORMAMIDE,N,N-BIS(2-CHLOROETHYL) 
CAS No.:
2619-97-8
分 子 式:
C6H11Cl2NO2.ClH
分 子 量:
236.54
精确分子量:
234.99300
PSA:
40.54000
InChI:
The Key: JUBAFYPBMDLOSF-UHFFFAOYSA-N
安全术语:
A deadly poison by intraperitoneal, intravenous, and intracerebral routes. When heated to decomposition it emits very toxic fumes of Cl− and NOx.
分子结构式:
SDS:
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物化性质

密度:
1.314g/cm3
沸点:
236ºC at 760 mmHg
闪点:
96.5ºC
折射率:
1.5
蒸汽压:
0.0167mmHg at 25°C

毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MB8480000
CHEMICAL NAME :
Glycine, N,N-bis(2-chloroethyl)-, hydrochloride
CAS REGISTRY NUMBER :
2619-97-8
LAST UPDATED :
199203
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C6-H11-Cl2-N-O2.Cl-H
MOLECULAR WEIGHT :
236.54
WISWESSER LINE NOTATION :
QV1N2G2G &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intracerebral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
113 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 18,760,1966
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
15 mg/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent
REFERENCE :
PHBUA9 Pharmaceutical Bulletin. (Tokyo, Japan) V.1-5, 1953-57. For publisher information, see CPBTAL. Volume(issue)/page/year: 2,275,1954
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
1 mg/kg
TOXIC EFFECTS :
Gastrointestinal - other changes Blood - leukopenia Blood - other changes
REFERENCE :
CCSUBJ Cancer Chemotherapy Reports, Part 2. (Washington, DC) V.1-5, 1964-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 2,201,1965
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Primate - monkey
DOSE/DURATION :
1 mg/kg
TOXIC EFFECTS :
Blood - leukopenia Blood - other changes
REFERENCE :
CCSUBJ Cancer Chemotherapy Reports, Part 2. (Washington, DC) V.1-5, 1964-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 2,201,1965

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