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乙基吗啡盐酸盐二水合物 基本信息
- 中文名称：
- 乙基吗啡盐酸盐二水合物
- 中文别名：
-
- 英文名称：
- Morphinan-6-ol,7,8-didehydro-4,5-epoxy-3-ethoxy-17-methyl-, hydrochloride, dihydrate, (5a,6a)- (9CI)
- 英文别名：
- (4R,4aR,7S,7aR,12bS)-9-ethoxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ol,dihydrate,hydrochloride;
UNII-407X3NQV4N;
C19H23NO3.2H2O.HCl;
Ethylmorphine Hydrochloride,Dihydrate,(5alpha,6alpha)-Isomer;
Ethylmorphine HCl hydrate;
Dionin;
Ethylmorphine hydrochloride dihydrate
- CAS No.：
- 6746-59-4
- 分 子 式：
- C19H23NO3.ClH.2H2O
- 分 子 量：
- 385.93
- 精确分子量：
- 313.16800
- PSA：
- 41.93000
- InChI：
- The Key: KAKUSMUSYSCWSI-JEWITJNGSA-N
- 安全术语：
- Poison by subcutaneous route. Can be habit forming. An experimental teratogen. When heated to decomposition it emits very toxic fumes of NOx and HCl. See also CODEINE and (−)-MORPHINE.
- 分子结构式：
-
- SDS：
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乙基吗啡盐酸盐二水合物 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QD0875000
- CHEMICAL NAME :
- Morphinan-6-alpha-ol,
7,8-didehydro-4,5-alpha-epoxy-3-ethoxy-17-methyl-,
hydrochloride, dihydrate
- CAS REGISTRY NUMBER :
- 6746-59-4
- LAST UPDATED :
- 199512
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C19-H23-N-O3.Cl-H.2H2-O
- MOLECULAR WEIGHT :
- 385.93
- WISWESSER LINE NOTATION :
- T B6566 B6/CO 4ABBC R BX HO PN DU GHT&&TTJ FQ JO2 P1
&GH &QH 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland,
OH, Chemical Rubber Co., 1969 Volume(issue)/page/year: -,53,1969
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 550 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935
** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 182 mg/kg
- SEX/DURATION :
- female 8 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - Central Nervous System
Reproductive - Specific Developmental Abnormalities - other developmental
abnormalities
- REFERENCE :
- AJOGAH American Journal of Obstetrics and Gynecology. (C.V. Mosby Co.,
11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1920-
Volume(issue)/page/year: 123,705,1975
