氨基乙腈盐酸盐

  • 基本信息
  • 制备方法及用途
  • 物化性质
  • 安全信息
  • 毒理性
  • MSDS
  • 海关数据
  • 结构与计算化学
  • 下游产品
  • 表征图谱

氨基乙腈盐酸盐 基本信息

中文名称:
氨基乙腈盐酸盐 
中文别名:
氨基乙腈盐酸盐;
盐酸胺腈;
甘氨基腈盐酸盐;
氨基乙氰盐酸盐 
英文名称:
Acetonitrile,2-amino-, hydrochloride (1:1)
英文别名:
Aminoacetonitrile Hydrochloride;
2-aminoacetonitrile,hydrochloride 
CAS No.:
6011-14-9
分 子 式:

C2H4N2.ClH

分 子 量:
92.53
精确分子量:
92.01410
PSA:
49.81000
MDL:
MFCD00012850
EINECS:
227-865-9
InChI:
InChI=1/C2H4N2.ClH/c3-1-2-4;/h1,3H2;1H
危险品标志:

 

风险术语:

R22; R36/37/38;

安全术语:

S26; S36/37/39;

分子结构式:
SDS:
查看

氨基乙腈盐酸盐 制备方法及用途

制备方法

用作医药中间体、有机合成原料

用途简介

用途

用作医药中间体、有机合成原料

氨基乙腈盐酸盐 物化性质

外观与性状:
白色至灰白色结晶粉末
熔点:
172-174°C
沸点:
164.2°C at 760 mmHg
闪点:
53.1ºC
存储条件/存储方法:

密封阴凉干燥保存。

稳定性相关:

常温常压下稳定

其它信息:

1.       性状:片状结晶。有吸湿性。

2.       密度(g/mL,25/4): 未确定

3.       相对蒸汽密度(g/mL,空气=1):未确定

4.       熔点(ºC):165(分解)

5.       沸点(ºC,常压):未确定

6.       沸点(ºC,5.2kPa):未确定

7.       折射率:未确定

8.       闪点(ºC):未确定

9.       比旋光度(º):未确定

10.    自燃点或引燃温度(ºC):未确定

11.    蒸气压(kPa,25ºC):未确定

12.    饱和蒸气压(kPa,60ºC):未确定

13.    燃烧热(KJ/mol):未确定

14.    临界温度(ºC):未确定

15.    临界压力(KPa):未确定

16.    油水(辛醇/水)分配系数的对数值:未确定

17.    爆炸上限(%,V/V):未确定

18.    爆炸下限(%,V/V):未确定

19.    溶解性:在空气中逐渐变红。微溶于乙醇和和乙醚。

氨基乙腈盐酸盐 安全信息

包装等级:
III
风险类别:
6.1
海关代码:
2926909090
危险类别码:
R22;R36/37/38
安全说明:
S22-S36/37

氨基乙腈盐酸盐 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MC1950000
CHEMICAL NAME :
Glycinonitrile, monohydrochloride
CAS REGISTRY NUMBER :
6011-14-9
LAST UPDATED :
199712
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C2-H4-N2.Cl-H
MOLECULAR WEIGHT :
92.54
WISWESSER LINE NOTATION :
Z1CN &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
600 mg/kg
SEX/DURATION :
female 3-7 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4)
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 24(2),41A,1981
毒理学数据:

繁殖数据:

小鼠腹膜最低毒剂LDLo600 ng/kg,母鼠受孕后3-7天用。生殖-生育-植入后死亡率(如死亡和或吸收植入总数)生殖-具体的发展异常-中枢神经系统生殖-对新生儿-断奶或哺乳指数(例如,断奶后存活时间为4天)。

生态数据:

该物质对环境可能有危害,对水体应给予特别注意

氨基乙腈盐酸盐 MSDS

Name: Aminoacetonitrile Hydrochloride 99% Material Safety Data Sheet
Synonym: Glycinonitrile Hydrochloride
CAS: 6011-14-9
Section 1 - Chemical Product   MSDS Name:Aminoacetonitrile Hydrochloride 99% Material Safety Data Sheet
Synonym:Glycinonitrile Hydrochloride

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
6011-14-9 Aminoacetonitrile Hydrochloride 99 227-865-9
Hazard Symbols: XN
Risk Phrases: 22

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
Harmful if swallowed.Hygroscopic (absorbs moisture from the air).The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
Adverse reproductive effects have been reported in animals.

Section 4 - FIRST AID MEASURES
  Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Section 7 - HANDLING and STORAGE
  Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 6011-14-9: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Solid
Color: white
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 172.00 - 174.00 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: >165 deg C
Solubility in water: soluble
Specific Gravity/Density:
Molecular Formula: C2H4N2.HCl
Molecular Weight: 92.53

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, strong oxidants, exposure to moist air or water.
Incompatibilities with Other Materials:
Moisture, strong oxidizing agents.
Hazardous Decomposition Products:
Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 6011-14-9: MC1950000 LD50/LC50:
Not available.
Carcinogenicity:
Aminoacetonitrile Hydrochloride - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
 

Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
 
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 22 Harmful if swallowed.
Safety Phrases:
S 28A After contact with skin, wash immediately with
plenty of water.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 6011-14-9: No information available.
Canada
CAS# 6011-14-9 is listed on Canada's NDSL List.
CAS# 6011-14-9 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 6011-14-9 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A

氨基乙腈盐酸盐 海关数据

中国海关编码:2926909090

概述:
2926909090 其他腈基化合物. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素:
品名, 成分含量, 用途
摘要/Summary:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

氨基乙腈盐酸盐 分子结构与计算化学数据

分子结构数据

1   摩尔折射率:14.76

2   摩尔体积(m3/mol):58.6

3   等张比容(90.2K):149.0

4   表面张力(dyne/cm):41.8

5   极化率(10-24cm3):5.85

计算化学数据

1.疏水参数计算参考值(XlogP):无

2.氢键供体数量:2

3.氢键受体数量:2

4.可旋转化学键数量:0

5.互变异构体数量:无

6.拓扑分子极性表面积49.8

7.重原子数量:5

8.表面电荷:0

9.复杂度:39.2

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:2

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