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基本信息
- 中文名称：
-
- 中文别名：
-
- 英文名称：
- Platinum,(1,2-ethanediamine-kN1,kN2)[propanedioato(2-)-kO1,kO3]-, (SP-4-2)-
- 英文别名：
- Platinum, (1,2-ethanediamine-N,N')(propanedioato(2-)-O,O')-, (SP-4-2)-;
1,3-Cyclopentadiene,1-ethyl-,zirconium complex
- CAS No.：
- 41666-77-7
- 分 子 式：
- C5H10N2O4Pt
- 分 子 量：
- 357.2279
- 精确分子量：
- 355.01300
- PSA：
- 76.66000
- InChI：
- The Key: JXDQXTJOVCSFJY-UHFFFAOYSA-L
- 分子结构式：
-
- SDS：
- 查看
物化性质
- 沸点：
- 386.8ºC at 760 mmHg
- 闪点：
- 201.9ºC
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TP2505500
- CHEMICAL NAME :
- Platinum (II), (ethylenediammine)malonato-
- CAS REGISTRY NUMBER :
- 41666-77-7
- LAST UPDATED :
- 199509
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C5-H10-N2-O4-Pt
- MOLECULAR WEIGHT :
- 357.26
- WISWESSER LINE NOTATION :
- Z2Z &QV1VQ &-PT-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 1080 ug/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - paresthesis
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - transaminases
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - other Enzymes
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
46,2148,1986
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BICHBX Bioinorganic Chemistry. (New York, NY) V.1-9, 1971-78.
Volume(issue)/page/year: 2,187,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 107 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - other changes
Kidney, Ureter, Bladder - other changes
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
46,2148,1986
** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 120 mg/kg/5D-I
- TOXIC EFFECTS :
- Liver - other changes
Blood - changes in bone marrow (not otherwise specified)
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - phosphatases
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: PB80-217292
