硝酸镉

外观与性状：

无气味的白色固体

密度：

2.455（17/4℃）

熔点：

59.4℃

沸点：

132℃

存储条件/存储方法：

库房通风低温干燥,轻装轻卸,与有机物、还原剂、硫、磷易燃物,食品原料分开存放

稳定性相关：

1.稳定性^[12]  稳定

2.禁配物^[13]  易燃或可燃物、硫、磷、还原剂、金属粉末等

3.避免接触的条件^[14]  受热

4.聚合危害^[15]  不聚合

5.分解产物^[16]  氮氧化物

其它信息：

1.性状：无色针状或棱形晶体，有吸潮性，在空气中会潮解。^[1]

2.熔点（℃）：350（分解）^[2]

3.沸点（℃）：132（四水合物）^[3]

4.相对密度（水=1）：3.6^[4]

5.溶解性：溶于水，溶于乙醇、丙酮、乙酸乙酯、乙醚。^[5]

包装等级：

II

风险类别：

6.1(b)

WGK_Germany：

3
德国有关水污染物质的分类清单

危险类别码：

R45

安全说明：

S53-S45-S36-S26-S36/37-S60

安全标志：

S36:穿戴合适的防护服装。
S60:本物质残余物和容器必须作为危险废物处理。

危险标志：

O:Oxidizingagent;T:Toxic;N:Dangerousfortheenvironment;

CHEMICAL IDENTIFICATION

RTECS NUMBER :

EV1750000

CHEMICAL NAME :

Cadmium nitrate

CAS REGISTRY NUMBER :

10325-94-7

LAST UPDATED :

199712

DATA ITEMS CITED :

40

MOLECULAR FORMULA :

N2-O6.Cd

MOLECULAR WEIGHT :

236.42

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

300 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Unreported

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

200 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

100 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

40 mg/kg

SEX/DURATION :

female 1-19 day(s) after conception

TOXIC EFFECTS :

Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated) Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

40 mg/kg

SEX/DURATION :

female 1-19 day(s) after conception

TOXIC EFFECTS :

Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4)

MUTATION DATA

TYPE OF TEST :

Sister chromatid exchange

TEST SYSTEM :

Rodent - hamster Ovary

REFERENCE :

EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 23,143,1994 *** REVIEWS *** ACGIH TLV-TWA 0.01 mg(Cd)/m3, inhalable dust DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 0.002 mg(Cd)/m3, respirable dust DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-Suspected human carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Human Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 58,119,1993 IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 58,119,1993 IARC Cancer Review:Group 1 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 58,119,1993 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 0.2 mg(Cd)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,34,1971 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 0.05 mg(Cd)/m3 JAN 1993 OEL-AUSTRALIA:TWA 0.05 mg(Cd)/m3 JAN 1993 OEL-BELGIUM:TWA 0.05 mg(Cd)/m3 JAN 1993 OEL-DENMARK:TWA 0.01 mg(Cd)/m3 JAN 1993 OEL-FINLAND:TWA 0.02 mg(Cd)/m3;Carcinogen JAN 1993 OEL-GERMANY;Carcinogen JAN 1993 OEL-INDIA:TWA 0.05 mg(Cd)/m3 JAN 1993 OEL-JAPAN:TWA 0.05 mg(Cd)/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 0.02 mg(Cd)/m3;STEL 0.1 mg(Cd)/m3 JAN 1993 OEL-THE PHILIPPINES:TWA 0.2 mg(Cd)/m3 JAN 1993 OEL-RUSSIA:TWA 0.01 mg(Cd)/m3;STEL 0.05 mg(Cd)/m3 JAN 1993 OEL-SWEDEN:TWA 0.02 mg(Cd)/m3;Carcinogen JAN 1993 OEL-SWITZERLAND:TWA 0.05 mg(Cd)/m3 JAN 1993 OEL-THAILAND:TWA 0.2 mg(Cd)/m3;STEL 0.5 mg(Cd)/m3 JAN 1993 OEL-TURKEY:TWA 0.2 mg(Cd)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 0.01 mg(Cd)/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO CADMIUM, dust and fume-air:CA lowest feasible conc. REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81749 No. of Facilities: 19 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 489 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81749 No. of Facilities: 169 (estimated) No. of Industries: 3 No. of Occupations: 4 No. of Employees: 1878 (estimated) No. of Female Employees: 378 (estimated)

毒理学数据：

1.急性毒性^[6]

LD50：300mg/kg（大鼠经口）；47mg/kg（小鼠经口）

LC50：3850mg/m³（小鼠吸入）

2.刺激性  暂无资料

3.致突变性^[7]  DNA修复：枯草杆菌5mmol/L。细胞遗传学分析：仓鼠卵巢1μmol/L。姐妹染色单体交换：仓鼠卵巢300nmol/L。

4.致畸性^[8]  雌性大鼠孕后1~19d经口染毒最低中毒剂量（TDLo）40mg/kg，致心血管系统发育畸形。

5.致癌性^[9]  IARC致癌性评论：IARC将镉及其化合物列为G1，确认人类致癌物。

生态数据：

1.生态毒性^[10]

LC50：0.055mg/L（48h）（虹鳟鱼）；0.802mg/L（48h）（黑头呆鱼）

EC50：0.16mg/L（24h）（水蚤）

2.生物降解性  暂无资料

3.非生物降解性  暂无资料

4.其他有害作用^[11]  该物质对环境有危害，镉元素在生物体内有很强的蓄积作用。

计算化学数据

1.疏水参数计算参考值（XlogP）:无

2.氢键供体数量:0

3.氢键受体数量:6

4.可旋转化学键数量:0

5.互变异构体数量:无

6.拓扑分子极性表面积126

7.重原子数量:9

8.表面电荷:0

9.复杂度:18.8

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:3