5-甲基异恶唑-3-羧酸甲酯

  • 基本信息
  • 制备方法及用途
  • 物化性质
  • 安全信息
  • 毒理性
  • MSDS
  • 海关数据
  • 结构与计算化学
  • 上游产品
  • 下游产品

5-甲基异恶唑-3-羧酸甲酯 基本信息

中文名称:
5-甲基异恶唑-3-羧酸甲酯 
中文别名:
5-甲基异恶唑-3-羧酸甲酯;
5-甲基异噁唑-3-羧酸甲酯;
5-甲基异唑-3-羧酸甲酯;
5-甲基异恶唑-3-羧酸 
英文名称:
3-Isoxazolecarboxylicacid, 5-methyl-, methyl ester
英文别名:
methyl 5-methyl-1,2-oxazole-3-carboxylate;
5-Methyl-isoxazol-3-carbonsaeure-methylester;
Methyl 5-Methylisoxazole-3-Carboxylate;
methyl-5-methylisoxazole-3-carboxylate;
5-methyl-isoxazole-3-carboxylic acid methyl ester;
3-Isoxazolecarboxylic acid,5-methyl-,methyl ester;
Methyl 5-methyl-3-isoxazolecarboxylate 
CAS No.:
19788-35-3
分 子 式:
C6H7NO3
分 子 量:
141.12
精确分子量:
141.04300
PSA:
52.33000
MDL:
MFCD00015895
EINECS:
243-311-9
BRN:
115704
InChI:
InChI=1/C6H7NO3/c1-4-3-5(7-10-4)6(8)9-2/h3H,1-2H3
风险术语:
36/37/38
安全术语:
S22; S24/25;
分子结构式:
SDS:
查看

5-甲基异恶唑-3-羧酸甲酯 制备方法及用途

制备方法

可用乙酰丙酮酸甲酯与盐酸羟胺环合制得。

合成制备方法

可用乙酰丙酮酸甲酯与盐酸羟胺环合制得。

用途简介

磺胺甲基异噁唑的中间体。

用途

磺胺甲基异噁唑的中间体。

5-甲基异恶唑-3-羧酸甲酯 物化性质

外观与性状:
白色至灰白色结晶粉末
密度:
1.179g/cm3
熔点:
90-92 °C
沸点:
125°C 11mm
闪点:
125°C/11mm
折射率:
1.468
蒸汽压:
0.064mmHg at 25°C
存储条件/存储方法:

在密封的贮藏器内,并放置阴凉,干燥的地方保存

稳定性相关:

如果按照规则使用和储存则不会分解

避免接触氧化物

其它信息:

1. 性状:未确定

2. 密度(g/mL,25/4):未确定

3. 相对蒸汽密度(g/mL,空气=1未确定

4. 熔点(ºC):90-92

5. 沸点(ºC,常压):未确定

6. 沸点(ºC,5.2kPa): 125°C 11mm

7. 折射率: 未确定

8. 闪点(ºC): 125°C/11mm

9. 比旋光度(º): 未确定

10. 自燃点或引燃温度(ºC): 未确定

11. 蒸气压(kPa,25ºC): 未确定

12. 饱和蒸气压(kPa,60ºC): 未确定

13. 燃烧热(KJ/mol):未确定

14. 临界温度(ºC): 未确定

15. 临界压力(KPa): 未确定

16. 油水(辛醇/水)分配系数的对数值: 未确定

17. 爆炸上限(%,V/V):未确定

18. 爆炸下限(%,V/V): 未确定

19. 溶解性:未确定

5-甲基异恶唑-3-羧酸甲酯 安全信息

海关代码:
2934999090
危险类别码:
R36/37/38
安全说明:
S24/25
安全标志:
S24/25:防止皮肤和眼睛接触。
危险标志:
Xi

5-甲基异恶唑-3-羧酸甲酯 毒理性

生态数据:

对水是稍微危害的,若无政府许可,勿将材料排入周围环境。

5-甲基异恶唑-3-羧酸甲酯 MSDS

Name: Methyl 5-methylisoxazole-3-carboxylate Material Safety Data Sheet
Synonym: None Known
CAS: 19788-35-3
Section 1 - Chemical Product   MSDS Name:Methyl 5-methylisoxazole-3-carboxylate Material Safety Data Sheet
Synonym:None Known

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
19788-35-3 Methyl 5-methylisoxazole-3-carboxylate 98 243-311-9
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. May be harmful if inhaled.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
  Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid.
Skin:
In case of contact, flush skin with plenty of water. Remove contaminated clothing and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

Section 7 - HANDLING and STORAGE
  Handling:
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing.
Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 19788-35-3: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Crystalline powder
Color: white to off-white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C6H7NO3
Molecular Weight: 141.13

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Dust generation.
Incompatibilities with Other Materials:
Acids, bases, reducing agents, oxidizing agents.
Hazardous Decomposition Products:
Hydrogen cyanide, carbon monoxide, oxides of nitrogen, carbon dioxide, nitric acid.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 19788-35-3 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Methyl 5-methylisoxazole-3-carboxylate - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION
 

Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
 
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 19788-35-3: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 19788-35-3 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 19788-35-3 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

5-甲基异恶唑-3-羧酸甲酯 海关数据

中国海关编码:2934999090

概述:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素:
品名, 成分含量, 用途
摘要/Summary:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

5-甲基异恶唑-3-羧酸甲酯 分子结构与计算化学数据

分子结构数据

 

五、分子性质数据:

1、   摩尔折射率:33.24

2、   摩尔体积(m3/mol)119.6

3、   等张比容(90.2K)297.8

4、   表面张力(dyne/cm)38.4

5、   极化率(10-24cm3)13.17

计算化学数据

1.疏水参数计算参考值(XlogP):无

2.氢键供体数量:0

3.氢键受体数量:4

4.可旋转化学键数量:2

5.互变异构体数量:无

6.拓扑分子极性表面积52.3

7.重原子数量:10

8.表面电荷:0

9.复杂度:137

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

5-甲基异恶唑-3-羧酸甲酯 上游产品

推荐供应商更多供应商>>

湖北云镁科技有限公司

产品介绍:
产品名称:5-甲基异噁唑-3-羧酸甲酯 Cas号:19788-35-3 纯度:99% 包装信息:1kg铝箔袋/氟化瓶,10kg铝听/纸箱,25kg纸板桶/编织袋/塑料桶 价格:1.0元 - 25.0元
联系方式:
联系人:方经理 电话:027-59206672 手机:18327059871

沧州恩科医药科技有限公司

产品介绍:
产品名称:5-甲基异恶唑-3-羧酸甲酯 Cas号:19788-35-3 纯度:98% 包装信息:100kg,200kg,300kg,400kg,500kg 价格:64.0元 - 100.0元
联系方式:
联系人:赵经理 电话:0317-5106598 手机:13323075105

上海吉至生化科技有限公司

产品介绍:
产品名称:5-甲基异恶唑-3-羧酸甲酯 Cas号:19788-35-3 纯度:96% 包装信息:1gea 价格:38.0元
联系方式:
联系人:江珊 电话:021-57520831 手机:15316869680

上海源叶生物科技有限公司

产品介绍:
产品名称:5-甲基异恶唑-3-羧酸甲酯 Cas号:19788-35-3 纯度:98% 包装信息:25g,5g 价格:100.0元 - 360.0元
联系方式:
联系人:Yuki 电话:021-61845781 手机:13585604150

湖北鑫鸣泰化学有限公司

产品介绍:
产品名称:5-甲基异恶唑-3-羧酸甲酯 Cas号:19788-35-3 纯度:99% 包装信息:100kg,200kg 价格:1.0元 - 1.0元
联系方式:
联系人:黄 电话:027-50662354 手机:13264726139

湖北江民泰华化工有限公司

产品介绍:
产品名称:5-甲基异恶唑-3-羧酸甲酯 Cas号:19788-35-3 纯度:99% 包装信息:25kg,200kg 价格:洽谈
联系方式:
联系人:张经理 电话:13396038321 手机:13396038321

湖北臻博化工有限公司

产品介绍:
产品名称:5-甲基异恶唑-3-羧酸甲酯 Cas号:19788-35-3 纯度:98% 包装信息:1kg,25kg,200kg 价格:洽谈
联系方式:
联系人:张经理 电话:18071535998 手机:18071535998

上海瀚思化工有限公司

产品介绍:
产品名称:5-甲基异恶唑-3-羧酸甲酯 Cas号:19788-35-3 纯度:96% 包装信息:1g 价格:124.8元
联系方式:
联系人:张 电话:021-64806089 手机:18049821080

北京偶合科技有限公司

产品介绍:
产品名称:5-甲基异恶唑-3-羧酸甲酯 Cas号:19788-35-3 纯度: 包装信息:洽谈 价格:洽谈
联系方式:
联系人:刘先生 电话:010-51280831(不占线);82967027 手机:13911808554

郑州希派克化工有限公司

产品介绍:
产品名称:5-甲基异噁唑-3-羧酸甲酯 Cas号:19788-35-3 纯度: 包装信息:洽谈 价格:洽谈
联系方式:
联系人:王丹 电话:0371-55695890 手机:13526885213