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蝥霉素 基本信息
- 中文名称：
- 蝥霉素
- 中文别名：
- 蝥霉素
- 英文名称：
- 1,12(4H,5H)-Naphthacenedione,2-acetyl-4-amino-4a,12a-dihydro-3,10,11,12a-tetrahydroxy-6,9-dimethyl-,(4R,4aS,12aS)-
- 英文别名：
- Chelocardin;
4-Oxo-1,4-dihydropyridine-2,6-dicarboxylic acid hydrate;
Chelidamic acid hydrate;
chelidamic acid monohydrate;
1,4-Dihydro-4-oxo-2,6-pyridinedicarboxylic acid hydrate
- CAS No.：
- 29144-42-1
- 分 子 式：
- C22H21NO7
- 分 子 量：
- 315.44
- 精确分子量：
- 411.13200
- PSA：
- 158.15000
- InChI：
- The Key: IRCLZBUBOWPFCH-ONJZCGHCSA-N
- 安全术语：
- Poison by ingestion, intraperitoneal, and intravenous routes. When heated to decomposition it emits toxic fumes of NOx.
- 分子结构式：
-
- SDS：
- 查看
蝥霉素 物化性质
- 密度：
- 1.572g/cm3
- 沸点：
- 673.4ºC at 760mmHg
- 闪点：
- 361.1ºC
- 折射率：
- 1.749
- 蒸汽压：
- 4.72E-19mmHg at 25°C
- 存储条件/存储方法：
- 库房低温通风干燥
蝥霉素 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QI9293000
- CHEMICAL NAME :
- 1,12-(4H,5H)-Naphthacenedione,
2-acetyl-4-alpha-amino-4a-beta,12a-dihydro-
3,10,11,12a-beta-tetrahydroxy-6,9-dimethyl-
- CAS REGISTRY NUMBER :
- 29144-42-1
- LAST UPDATED :
- 199112
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C22-H21-N-O7
- MOLECULAR WEIGHT :
- 411.44
- WISWESSER LINE NOTATION :
- L E6 C666 BV RV PU&&TTJ AQ DQ FQ G1 K1 OZ PQ QV1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AACHAX Antimicrobial Agents and Chemotherapy (1961-70). (Ann Arbor, MI)
1961-70. For publisher information, see AMACCQ. Volume(issue)/page/year:
-,583,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 140 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AACHAX Antimicrobial Agents and Chemotherapy (1961-70). (Ann Arbor, MI)
1961-70. For publisher information, see AMACCQ. Volume(issue)/page/year:
-,583,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 88 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AACHAX Antimicrobial Agents and Chemotherapy (1961-70). (Ann Arbor, MI)
1961-70. For publisher information, see AMACCQ. Volume(issue)/page/year:
-,583,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 89 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AACHAX Antimicrobial Agents and Chemotherapy (1961-70). (Ann Arbor, MI)
1961-70. For publisher information, see AMACCQ. Volume(issue)/page/year:
-,583,1962
