产品供求
倍美西林 基本信息
- 中文名称：
- 倍美西林
- 中文别名：
- 倍美西林;
巴美西林
- 英文名称：
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-,1-[(ethoxycarbonyl)oxy]ethyl ester, (2S,5R,6R)-
- 英文别名：
- 1-ethoxycarbonyloxyethyl (2S,5R,6R)-6-(azepan-1-ylmethylideneamino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;
ethyl 6-ethoxy-4-thioxo-7-oxa-2,3,5-triaza-6-phosphanonan-1-oate 6-oxide;
1'-Aethoxycarbonyloxyaethyl-6-(hexahydro-1H-azepin-1-yl)-methylenaminopenicillanat;
ETHYL N-(DIETHOXYPHOSPHORYLTHIOCARBAMOYLAMINO)CARBAMATE;
1-Aethoxycarbonyl-4-diaethylphosphono-thiosemicarbazid
- CAS No.：
- 50846-45-2
- 分 子 式：
- C20H31N3O6S
- 分 子 量：
- 441.54
- 精确分子量：
- 441.19300
- PSA：
- 123.04000
- InChI：
- The Key: XHKFBADIZIDYBU-UHFFFAOYSA-N
- 风险术语：
- R20/21/22; R36/37/38
- 安全术语：
- An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx and NOx.
- 分子结构式：
-
- SDS：
- 查看
倍美西林 物化性质
- 密度：
- 1.36g/cm3
- 沸点：
- 578.2ºC at 760mmHg
- 闪点：
- 303.5ºC
- 折射率：
- 1.612
倍美西林 安全信息
- 危险类别码：
- 20/21/22-36/37/38
- 危险标志：
- Xn
倍美西林 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XI0186000
- CHEMICAL NAME :
- 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid,
6-(((hexahydro-1H-azepin-1-yl)methylene)
amino)-3,3-dimethyl-7-oxo-,
1-((ethoxycarbonyl)oxy)ethyl ester,
(2S-(2-alpha,5-alpha,6-beta))-
- CAS REGISTRY NUMBER :
- 50846-45-2
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C20-H31-N3-O6-S
- MOLECULAR WEIGHT :
- 441.60
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 11200 mg/kg/35D-I
- TOXIC EFFECTS :
- Gastrointestinal - hypermotility, diarrhea
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
- REFERENCE :
- NKRZAZ Chemotherapy (Tokyo). (Nippon Kagaku Ryoho Gakkai, 2-20-8 Kamiosaki,
Shinagawa-Ku, Tokyo 141, Japan) V.1- 1953- Volume(issue)/page/year:
33(Suppl 3),60,1985
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 57600 mg/kg/26W-I
- TOXIC EFFECTS :
- Gastrointestinal - nausea or vomiting
Liver - other changes
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - dehydrogenases
- REFERENCE :
- NKRZAZ Chemotherapy (Tokyo). (Nippon Kagaku Ryoho Gakkai, 2-20-8 Kamiosaki,
Shinagawa-Ku, Tokyo 141, Japan) V.1- 1953- Volume(issue)/page/year:
33(Suppl 3),60,1985
** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 4950 mg/kg
- SEX/DURATION :
- female 7-17 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
gain)
- REFERENCE :
- NKRZAZ Chemotherapy (Tokyo). (Nippon Kagaku Ryoho Gakkai, 2-20-8 Kamiosaki,
Shinagawa-Ku, Tokyo 141, Japan) V.1- 1953- Volume(issue)/page/year:
33(Suppl 3),78,1985
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 35100 mg/kg
- SEX/DURATION :
- female 17 day(s) after conception - 21 day(s)
post-birth
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
gain)
- REFERENCE :
- NKRZAZ Chemotherapy (Tokyo). (Nippon Kagaku Ryoho Gakkai, 2-20-8 Kamiosaki,
Shinagawa-Ku, Tokyo 141, Japan) V.1- 1953- Volume(issue)/page/year:
33(Suppl 3),78,1985
