卡那霉素 B

密度：

1.59g/cm3

沸点：

807.7ºC at 760mmHg

闪点：

442.3ºC

折射率：

1.668

存储条件/存储方法：

通风低温干燥

CHEMICAL IDENTIFICATION

RTECS NUMBER :

WK1975000

CHEMICAL NAME :

D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6 -diamino-2,6-dideoxy- alpha-D-glucopyranosyl-(1-6))-2-deoxy-

CAS REGISTRY NUMBER :

4696-76-8

BEILSTEIN REFERENCE NO. :

0061646

LAST UPDATED :

199612

DATA ITEMS CITED :

4

MOLECULAR FORMULA :

C18-H37-N5-O10

MOLECULAR WEIGHT :

483.60

WISWESSER LINE NOTATION :

T6OTJ CZ DQ EQ F1Z BO- BL6TJ AZ CQ EZ DO- BT6OTJ CQ DZ EQ F1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

800 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 1,159,1980

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

750 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 1,159,1980

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

132 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 27,677,1974