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- 盐酸布替林; 盐酸乙丁替林; (+/-)-10,11-二氢-N,N,beta-三甲基-5H-二苯并[a,d]环己烯-5-丙胺盐酸盐
盐酸布替林; 盐酸乙丁替林; (+/-)-10,11-二氢-N,N,beta-三甲基-5H-二苯并[a,d]环己烯-5-丙胺盐酸盐
盐酸布替林; 盐酸乙丁替林; (+/-)-10,11-二氢-N,N,beta-三甲基-5H-二苯并[a,d]环己烯-5-丙胺盐酸盐 基本信息
- 中文名称：
- 盐酸布替林; 盐酸乙丁替林; (+/-)-10,11-二氢-N,N,beta-三甲基-5H-二苯并[a,d]环己烯-5-丙胺盐酸盐
- 中文别名：
- 盐酸布替林;
(+/-)-10,11-二氢-N,N,BETA-三甲基-5H-二苯并[A,D]环己烯-5-丙胺盐酸盐;
盐酸乙丁替林
- 英文名称：
- 5H-Dibenzo[a,d]cycloheptene-5-propanamine,10,11-dihydro-N,N,b-trimethyl-, hydrochloride (1:1)
- 英文别名：
- Butriptyline hydrochloride;
ButriptylineHCl;
Evadyne;
Butriptylene hydrochloride;
Butriptylin*HCl
- CAS No.：
- 5585-73-9
- 分 子 式：
- C21H27N.ClH
- 分 子 量：
- 329.91
- 精确分子量：
- 329.19100
- PSA：
- 3.24000
- EINECS：
- 226-983-8
- InChI：
- The Key: MCWAFEJHLHEFOD-UHFFFAOYSA-N
- 分子结构式：
-
- SDS：
- 查看
盐酸布替林; 盐酸乙丁替林; (+/-)-10,11-二氢-N,N,beta-三甲基-5H-二苯并[a,d]环己烯-5-丙胺盐酸盐 物化性质
- 密度：
- 0.994g/cm3
- 熔点：
- 188-190ºC
- 沸点：
- 387.7ºC at 760 mmHg
- 闪点：
- 168.8ºC
- 折射率：
- 1.554
- 存储条件/存储方法：
- 库房通风低温干燥,与食品原料类分开存放
盐酸布替林; 盐酸乙丁替林; (+/-)-10,11-二氢-N,N,beta-三甲基-5H-二苯并[a,d]环己烯-5-丙胺盐酸盐 安全信息
盐酸布替林; 盐酸乙丁替林; (+/-)-10,11-二氢-N,N,beta-三甲基-5H-二苯并[a,d]环己烯-5-丙胺盐酸盐 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- HP0350000
- CHEMICAL NAME :
- 5H-Dibenzo(a,d)cycloheptene-5-propylamine,
10,11-dihydro-N,N,beta-trimethyl-, hydrochloride, DL-
- CAS REGISTRY NUMBER :
- 5585-73-9
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C21-H27-N.Cl-H
- MOLECULAR WEIGHT :
- 329.95
- WISWESSER LINE NOTATION :
- L C676&T&J B1Y1&1N1&1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 700 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,62,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 150 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,62,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 345 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,62,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 120 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,62,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 48 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,62,1972
