2,6-二甲基-3-羟基吡啶

  • 基本信息
  • 物化性质
  • 安全信息
  • 毒理性
  • MSDS
  • 海关数据
  • 结构与计算化学
  • 上游产品
  • 表征图谱

2,6-二甲基-3-羟基吡啶 基本信息

中文名称:
2,6-二甲基-3-羟基吡啶 
中文别名:
2,6-二甲基吡啶-3-醇;
2,6-二甲基-3-羟基吡啶;
2,6-二甲基-3-羟基吡啶2,6-二甲基-3-羟基吡啶 
英文名称:
3-Pyridinol,2,6-dimethyl-
英文别名:
2,6-dimethylpyridin-3-ol;
2,6-Dimethyl-3-hydroxypyridine;
2,6-Dimethyl-3-pyridinol;
2,6-dimethyl-pyridin-3-ol;
EINECS 214-348-8;
2,6-DIMETHYL-PYRIDIN-3-OL;
2,6-Dimethyl-3-oxypyridine;
3-Pyridinol,2,6-dimethyl;
2,6-dimethyl-3-hydroxypyridine;
3-hydroxy-2,6-dimethylpyridine 
CAS No.:
1122-43-6
分 子 式:
C7H9NO
分 子 量:
123.15
精确分子量:
123.06800
PSA:
33.12000
EINECS:
214-348-8
InChI:
InChI=1/C7H9NO/c1-5-3-4-7(9)6(2)8-5/h3-4,9H,1-2H3
危险品标志:
风险术语:
R36/37/38   
安全术语:
S26;S37/39
分子结构式:
SDS:
查看

2,6-二甲基-3-羟基吡啶 物化性质

密度:
1.083 g/cm3
熔点:
210-212°C
沸点:
278.9ºC at 760 mmHg
闪点:
122.4ºC
折射率:
1.544
蒸汽压:
0.00246mmHg at 25°C
其它信息:

1.       性状:白色固体结晶

2.       密度(g/cm3,25/4):未确定

3.       相对蒸汽密度(g/mL,空气=1):未确定

4.       熔点(ºC):210-212

5.       沸点(ºC,常压):未确定

6.       沸点(ºC,1.5mmHg):未确定

7.       折射率(n20/D)完全

8.       闪点(ºF):未确定

9.       比旋光度(º):未确定

10.    自燃点或引燃温度(ºC):未确定

11.    蒸气压(mmHg,20ºC):未确定

12.    饱和蒸气压(kPa,60ºC):未确定

13.    燃烧热(KJ/mol):未确定

14.    临界温度(ºC):未确定

15.    临界压力(KPa):未确定

16.    油水(辛醇/水)分配系数的对数值:未确定

17.    爆炸上限(%,V/V):未确定

18.    爆炸下限(%,V/V):未确定

19.    溶解性:未确定

2,6-二甲基-3-羟基吡啶 安全信息

海关代码:
2933399090
危险类别码:
R36/37/38
安全说明:
S26-S36/37/39
危险标志:
Xi:Irritant;

2,6-二甲基-3-羟基吡啶 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UU7712100
CHEMICAL NAME :
3-Pyridinol, 2,6-dimethyl-
CAS REGISTRY NUMBER :
1122-43-6
BEILSTEIN REFERENCE NO. :
0111008
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C7-H9-N-O
MOLECULAR WEIGHT :
123.17
WISWESSER LINE NOTATION :
T6NJ B1 CQ F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
675 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay)
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 16,259,1982

2,6-二甲基-3-羟基吡啶 MSDS

Name: 2 6-Dimethylpyridin-3-ol 97% Material Safety Data Sheet
Synonym:
CAS: 1122-43-6
Section 1 - Chemical Product   MSDS Name:2 6-Dimethylpyridin-3-ol 97% Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
1122-43-6 2,6-Dimethylpyridin-3-ol 97% 214-348-8
Hazard Symbols: XI
Risk Phrases: 36/37/38

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
  Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
  Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 1122-43-6: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Solid
Color: white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 180 deg C(decom)
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C7H9NO
Molecular Weight: 123

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents, acid chlorides.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, acrid smoke and fumes.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 1122-43-6: UU7712100 LD50/LC50:
Not available.
Carcinogenicity:
2,6-Dimethylpyridin-3-ol - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
 

Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
 
IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 1122-43-6: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 1122-43-6 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 1122-43-6 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

2,6-二甲基-3-羟基吡啶 海关数据

中国海关编码:2933399090

概述:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素:
品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
摘要/Summary:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2,6-二甲基-3-羟基吡啶 分子结构与计算化学数据

分子结构数据

1、   摩尔折射率:35.87

2、   摩尔体积m3/mol113.6

3、   等张比容90.2K291.7

4、   表面张力dyne/cm: 43.4

5、   介电常数:无可用

6、   偶极距10-24cm3:无可用

7、   极化率:14.22

计算化学数据

1.疏水参数计算参考值(XlogP):1.3

2.氢键供体数量:1

3.氢键受体数量:2

4.可旋转化学键数量:0

5.互变异构体数量:3

6.拓扑分子极性表面积33.1

7.重原子数量:9

8.表面电荷:0

9.复杂度:94.9

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

2,6-二甲基-3-羟基吡啶 表征图谱

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