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- 屈洛昔芬; 屈洛昔酚; 3-[1-[4-(2-二甲基氨基乙氧基)苯基]-2-苯基丁-1-烯基]苯酚
屈洛昔芬; 屈洛昔酚; 3-[1-[4-(2-二甲基氨基乙氧基)苯基]-2-苯基丁-1-烯基]苯酚
屈洛昔芬; 屈洛昔酚; 3-[1-[4-(2-二甲基氨基乙氧基)苯基]-2-苯基丁-1-烯基]苯酚 基本信息
- 中文名称：
- 屈洛昔芬; 屈洛昔酚; 3-[1-[4-(2-二甲基氨基乙氧基)苯基]-2-苯基丁-1-烯基]苯酚
- 中文别名：
- 屈洛昔芬;
3-[1-[4-(2-二甲基氨基乙氧基)苯基]-2-苯基丁-1-烯基]苯酚;
屈洛昔酚
- 英文名称：
- Phenol,3-[(1E)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-
- 英文别名：
- 3-[(E)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol;
K 060;
(E)-1-(4'-(2-dimethylaminoethoxy)phenyl)-1-(3-hydroxyphenyl)-2-phenylbut-1-ene;
K 060E;
3-Hydroxytamoxifen;
E-Droloxifene;
Droloxifenum [Latin];
FK-435;
Droloxifeno [Spanish];
E-1-[4'-(2-dimethylaminoethoxy)-phenyl]-1-(3'-hydroxyphenyl)-2-phenyl-1-butene;
Droloxifene
- CAS No.：
- 82413-20-5
- 分 子 式：
- C26H29NO2
- 分 子 量：
- 387.52
- 精确分子量：
- 579.24700
- PSA：
- 164.83000
- InChI：
- The Key: ZQZFYGIXNQKOAV-OCEACIFDSA-N
- 分子结构式：
-
- SDS：
- 查看
屈洛昔芬; 屈洛昔酚; 3-[1-[4-(2-二甲基氨基乙氧基)苯基]-2-苯基丁-1-烯基]苯酚 物化性质
- 外观与性状：
- 灰白色至灰白的-米色固体
- 密度：
- 1.092 g/cm3
- 熔点：
- 127-129ºC
- 沸点：
- 526.6ºC at 760 mmHg
- 折射率：
- 1.596
屈洛昔芬; 屈洛昔酚; 3-[1-[4-(2-二甲基氨基乙氧基)苯基]-2-苯基丁-1-烯基]苯酚 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SL1209900
- CHEMICAL NAME :
- Phenol,
3-(1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenyl-1-b
utenyl)-, (E)-
- CAS REGISTRY NUMBER :
- 82413-20-5
- LAST UPDATED :
- 199704
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C26-H29-N-O2
- MOLECULAR WEIGHT :
- 387.56
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >4500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540,
08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year:
9,186,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540,
08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year:
9,186,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >3 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540,
08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year:
9,186,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540,
08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year:
9,186,1984
*** REVIEWS ***
IARC Cancer Review:Human Inadequate Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 66,241,1996
IARC Cancer Review:Animal Inadequate Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 66,241,1996
IARC Cancer Review:Group 3
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 66,241,1996
屈洛昔芬; 屈洛昔酚; 3-[1-[4-(2-二甲基氨基乙氧基)苯基]-2-苯基丁-1-烯基]苯酚 上游产品
上海吉至生化科技有限公司
- 产品介绍：
-
产品名称：屈洛昔芬
Cas号：82413-20-5
纯度：98%
包装信息：5mgea
价格：2,498.0元
- 联系方式：
-
联系人：江珊
电话：021-57520831
手机：15316869680
