双咪苯脲; N,N'-二(3-(4,5-二氢-1H-咪唑-2-基)苯基)脲; 咪多卡

  • 基本信息
  • 制备方法及用途
  • 物化性质
  • MSDS

双咪苯脲; N,N'-二(3-(4,5-二氢-1H-咪唑-2-基)苯基)脲; 咪多卡 基本信息

中文名称:
双咪苯脲; N,N'-二(3-(4,5-二氢-1H-咪唑-2-基)苯基)脲; 咪多卡 
中文别名:
咪多卡;
N,N'-二(3-(4,5-二氢-1H-咪唑-2-基)苯基)脲;
3,3’-双(α-咪唑啉-α-基)均二苯脲;
双咪苯脲;
咪唑苯脲 
英文名称:
imidocarb
英文别名:
imidocarb;
Imidocarb;
IMIDOCARB BASE;
carbesia;
3,3'-Di-2-imidazolin-2-ylcarbanilid 
CAS No.:
27885-92-3
分 子 式:

C19H20N6O

分 子 量:
348.41
精确分子量:
496.24300
PSA:
164.51000
EINECS:
248-711-7
InChI:
InChI=1/C19H20N6O.2C3H6O2/c26-19(24-15-5-1-3-13(11-15)17-20-7-8-21-17)25-16-6-2-4-14(12-16)18-22-9-10-23-18;2*1-2-3(4)5/h1-6,11-12H,7-10H2,(H,20,21)(H,22,23)(H2,24,25,26);2*2H2,1H3,(H,4,5)
危险品标志:

 

风险术语:

 

安全术语:

 

分子结构式:
SDS:
查看

双咪苯脲; N,N'-二(3-(4,5-二氢-1H-咪唑-2-基)苯基)脲; 咪多卡 制备方法及用途

制备方法

将间硝基苯甲酸乙酯在三甲基铝存在下与乙二胺反应,制得2-(3-硝基苯)咪唑啉,收率90%。然后还原成2-(3-氨基苯)咪唑啉,最后经光气化,缩合得到咪唑脲。

用途简介

该品为抗焦虫病药物,具有疗效高、毒性低、剂量小的特点。对严重感染的牛、羊、巴贝西焦虫病,用咪唑脲治疗,病情可迅速得到控制,治疗三个月后未见复发。该品对焦虫病也有预防作用。

双咪苯脲; N,N'-二(3-(4,5-二氢-1H-咪唑-2-基)苯基)脲; 咪多卡 物化性质

密度:
1.39g/cm3
沸点:
677.1ºC at 760 mmHg
闪点:
363.3ºC
蒸汽压:
2.94E-19mmHg at 25°C

双咪苯脲; N,N'-二(3-(4,5-二氢-1H-咪唑-2-基)苯基)脲; 咪多卡 MSDS

  Material Safety Data Sheet

Section 1. Identification of the substance
    Product Name:      Imidocarb    
    Synonyms:

Section 2. Hazards identification
    Harmful by inhalation, in contact with skin, and if swallowed.

Section 3. Composition/information on ingredients.
    Ingredient name:        Imidocarb    
    CAS number:        27885-92-3    

Section 4. First aid measures
    Skin contact:        Immediately wash skin with copious amounts of water for at least 15 minutes while removing    
    contaminated clothing and shoes. If irritation persists, seek medical attention.
    Eye contact:        Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate    
    flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
    attention.
    Inhalation:        Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.    
    Ingestion:        Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.    

Section 5. Fire fighting measures
    In the event of a fire involving this material, alone or in combination with other materials, use dry
    powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
    should be worn.

Section 6. Accidental release measures
    Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
    standards.
    Respiratory precaution:        Wear approved mask/respirator    
    Hand precaution:        Wear suitable gloves/gauntlets    
    Skin protection:        Wear suitable protective clothing    
    Eye protection:        Wear suitable eye protection    
    Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
    for disposal. See section 12.
    Environmental precautions: Do not allow material to enter drains or water courses.

Section 7. Handling and storage
    Handling:        This product should be handled only by, or under the close supervision of, those properly qualified    
    in the handling and use of potentially hazardous chemicals, who should take into account the fire,
    health and chemical hazard data given on this sheet.
    Store in closed vessels.
    Storage:

Section 8. Exposure Controls / Personal protection
    Engineering Controls: Use only in a chemical fume hood.
    Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
    General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section 9. Physical and chemical properties
    Appearance:        Not specified    
    Boiling point:        No data    
    No data
    Melting point:
    Flash point:        No data    
    Density:        No data    
    Molecular formula:        C19H20N6O    
    Molecular weight:        348.4    

Section 10. Stability and reactivity
    Conditions to avoid: Heat, flames and sparks.
    Materials to avoid: Oxidizing agents.
    Possible hazardous combustion products: Carbon monoxide, nitrogen oxides.

Section 11. Toxicological information
    No data.

Section 12. Ecological information
    No data.

Section 13. Disposal consideration
    Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
    disposal authority, in accordance with national and regional regulations.

Section 14. Transportation information
    Non-harzardous for air and ground transportation.

Section 15. Regulatory information
    No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
    302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
    Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

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