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- (5alpha,6alpha)-17-甲基-4,5-环氧吗喃-3,6-二醇盐酸盐(1:1)
(5alpha,6alpha)-17-甲基-4,5-环氧吗喃-3,6-二醇盐酸盐(1:1)
(5alpha,6alpha)-17-甲基-4,5-环氧吗喃-3,6-二醇盐酸盐(1:1) 基本信息
- 中文名称：
- (5alpha,6alpha)-17-甲基-4,5-环氧吗喃-3,6-二醇盐酸盐(1:1)
- 中文别名：
-
- 英文名称：
- Morphinan-3,6-diol,4,5-epoxy-17-methyl-, hydrochloride, (5a,6a)- (9CI)
- 英文别名：
- Morphinan-3,6-diol,4,5-epoxy-17-methyl-, hydrochloride, (5a,6a)- (9CI);
Dihydromorphine hydrochloride;
Morphine,dihydro-,hydrochloride;
morphine hydrochloride
- CAS No.：
- 1421-28-9
- 分 子 式：
- C17H21NO3.ClH
- 分 子 量：
- 323.85
- 精确分子量：
- 323.12900
- PSA：
- 52.93000
- InChI：
- The Key: DZGJPYLWWJSNCT-VYKNHSEDSA-N
- 安全术语：
- Poison by subcutaneous, intravenous, and parenteral routes. Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of NOx and HCl. See also (−)-MORPHINE.
- 分子结构式：
-
- SDS：
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(5alpha,6alpha)-17-甲基-4,5-环氧吗喃-3,6-二醇盐酸盐(1:1) 物化性质
- 沸点：
- 475.4ºC at 760mmHg
- 闪点：
- 241.3ºC
- 蒸汽压：
- 7.65E-10mmHg at 25°C
(5alpha,6alpha)-17-甲基-4,5-环氧吗喃-3,6-二醇盐酸盐(1:1) 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QD4200000
- CHEMICAL NAME :
- Morphine, dihydro-, hydrochloride
- CAS REGISTRY NUMBER :
- 1421-28-9
- LAST UPDATED :
- 199512
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C17-H21-N-O3.Cl-H
- MOLECULAR WEIGHT :
- 323.85
- WISWESSER LINE NOTATION :
- T B6566 B6/CO 4ABBC R BX HO PN GHT&&TTJ EQ JQ P1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 149 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement
Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 52,468,1934
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 186 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 66,182,1939
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935
(5alpha,6alpha)-17-甲基-4,5-环氧吗喃-3,6-二醇盐酸盐(1:1) 上游产品
(5alpha,6alpha)-17-甲基-4,5-环氧吗喃-3,6-二醇盐酸盐(1:1) 下游产品
