Section 1. Chemical Product and Company Identification
Pergolide Mesylate
Common Name/
Trade Name
Pergolide Mesylate
Section 4. First Aid Measures
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least
Eye Contact
15 minutes. Cold water may be used. Get medical attention.
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated
Skin Contact
clothing and shoes. Cover the irritated skin with an emollient. Cold water may be used.Wash clothing before reuse.
Thoroughly clean shoes before reuse. Get medical attention immediately.
Serious Skin Contact Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate
medical attention.
Inhalation If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention immediately.
Serious Inhalation Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband.
WARNING: It may be hazardous to the person providing aid to give mouth-to-mouth resuscitation when the inhaled
material is toxic, infectious or corrosive. Seek immediate medical attention.
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to
Ingestion
an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention
immediately.
Not available.
Serious Ingestion
Section 5. Fire and Explosion Data
Flammability of the Product May be combustible at high temperature.
Auto-Ignition Temperature Not available.
Not available.
Flash Points
Not available.
Flammable Limits
These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), sulfur oxides (SO2, SO3...).
Products of Combustion
Fire Hazards in Presence of Slightly flammable to flammable in presence of heat.
Non-flammable in presence of shocks.
Various Substances
Risks of explosion of the product in presence of mechanical impact: Not available.
Explosion Hazards in
Slightly explosive in presence of open flames and sparks.
Presence of Various
Substances
SMALL FIRE: Use DRY chemical powder.
Fire Fighting Media
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
and Instructions
As with most organic solids, fire is possible at elevated temperatures
Special Remarks on
Fire Hazards
Fine dust dispersed in air in sufficient concentrations, and in the presences of an ignition source is a potential dust
Special Remarks on
explosion hazard.
Explosion Hazards
Section 6. Accidental Release Measures
Use appropriate tools to put the spilled solid in a convenient waste disposal container.
Small Spill
Poisonous solid.
Large Spill
Stop leak if without risk. Do not get water inside container. Do not touch spilled material. Use water spray to reduce
for assistance on disposal.
Pergolide Mesylate
Section 7. Handling and Storage
Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not
Precautions
ingest. Do not breathe dust. Wear suitable protective clothing. In case of insufficient ventilation, wear suitable
respiratory equipment. If ingested, seek medical advice immediately and show the container or the label. Avoid
contact with skin and eyes.
Keep container tightly closed. Keep container in a cool, well-ventilated area. Sensitive to light. Store in
Storage
light-resistant containers.
Section 8. Exposure Controls/Personal Protection
Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
Engineering Controls
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Personal Protection Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Personal Protection in Case Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to
avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE
of a Large Spill
handling this product.
Not available.
Exposure Limits
Section 9. Physical and Chemical Properties
Solid. Perceptible odor (Slight.)
Physical state and O dor
appearance
Not available.
Taste
410.64 g/mole
Molecular Weight
White.
Color
Not available.
pH (1% soln/water)
Not available.
Boiling Point
Decomposition temperature: 225°C (437°F)
Melting Point
Not available.
Critical Temperature
Not available.
Specific Gravity
Not applicable.
Vapor Pressure
Not available.
Vapor Density
Not available.
Volatility
Not available.
Odor Threshold
Not available.
Water/Oil Dist. Coeff.
Not available.
Ionicity (in Water)
See solubility in water.
Dispersion Properties
Very slightly soluble in cold water.
Solubility
Soluble in most organic substances
Pergolide Mesylate
Section 10. Stability and Reactivity Data
The product is stable.
Stability
Not available.
Instability Temperature
Conditions of Instability Excess heat, dust generation, incompatible materials
Incompatibility with various Not available.
substances
Not available.
Corrosivity
Not available.
Special Remarks on
Reactivity
Not available.
Special Remarks on
Corrosivity
Will not occur.
Polymerization
Section 11. Toxicological Information
Inhalation. Ingestion.
Routes of Entry
Toxicity to Animals Acute oral toxicity (LD50): 8.4 mg/kg [Rat].
Chronic Effects on Humans May cause damage to the following organs: cardiovascular system, central nervous system (CNS).
Very hazardous in case of ingestion, .
Other Toxic Effects on
Humans Hazardous in case of skin contact (irritant), of inhalation (lung irritant).
Not available.
Special Remarks on
Toxicity to Animals
May cause adverse reproductive effects and birth defects (teratogenic)
Special Remarks on
Chronic Effects on Humans
Acute Potential Health Effects:
Special Remarks on other
Skin: Causes skin irritation.
Toxic Effects on Humans
Eyes: Causes eye irritation.
Inhalation: Harmful if inhaled. Causes respiratory tract irritation.
Ingestion: May be fatal if swallowed. Causes gastrointestinal tract irritation with nausea, and vomiting. May also
affect behavior/central nervous system (temor, excitement, hallucinations, aggression, convulsions), metabolsim, and
respiratory system (respiratory stimulation), cardiovascular system, eyes (ptosis, pupillary dilation).
Chronic Potential Health Effects:
Ingestion: Repeated or prolonged ingestion may also affect behavior/central nervous system), blood (red and white
blood cell count), metabolism (weight loss), prostate, ovaries (changes in prostate and ovarian weight).
Section 12. Ecological Information
Not available.
Ecotoxicity
Not available.
BOD5 and COD
Products of Biodegradation Possibly hazardous short term degradation products are not likely. However, long term degradation products may
arise.
The products of degradation are less toxic than the product itself.
Toxicity of the Products
of Biodegradation
Not available.
Special Remarks on the
Products of Biodegradation
Pergolide Mesylate
Section 13. Disposal Considerations
Waste must be disposed of in accordance with federal, state and local environmental control
Waste Disposal
regulations.
Section 14. Transport Information
CLASS 6.1: Poisonous material.
DO T Cl assi fi cati on
UNNA: 2811 : Toxic Solid, Organic, n.o.s. (Pergolide Mesylate) PG: II
Identification
Not available.
Special Provisions for
Transport
DO T (Pi ctograms)
Section 15. Other Regulatory Information and Pictograms
No products were found.
Federal and State
Regulations
California prop. 65: This product contains the following ingredients for which the State of California has found to
California
cause cancer which would require a warning under the statute: No products were found.
Proposition 65
Warnings
California prop. 65: This product contains the following ingredients for which the State of California has found to
cause birth defects which would require a warning under the statute: No products were found.
Other Regulations OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
EINECS: This product is not on the European Inventory of Existing Commercial Chemical Substances.
Canada: Not listed on Canadian Domestic Substance List (DSL) or Canadian Non- Domestic Substance List (NDSL).
China: Not listed on National Inventory.
Japan: Not listed on National Inventory (ENCS).
Korea: Not listed on National Inventory (KECI).
Philippines: Not listed on National Inventory (PICCS).
Australia: Not listed on AICS.
WHMIS (Canada) It has not been classified by the Service du repertoire toxicologique. However, it may fall
Other Classifications
into the CLASS D-1A: Material causing immediate and serious toxic effects (VERY TOXIC).
R26/27/28- Very toxic by inhalation, in S22- Do not breathe dust.
DSCL (EEC)
contact with skin and if swallowed. S26- In case of contact with eyes, rinse
R36/37/38- Irritating to eyes, respiratory immediately with plenty of water and seek
system and skin. medical advice.
R40- Limited evidence of a S36/37/39- Wear suitable protective clothing,
carcinogenic effect. gloves and eye/face protection.
R60- May impair fertility. S38- In case of insufficient ventilation, wear
R63- Possible risk of harm to the unborn suitable respiratory equipment.
child. S45- In case of accident or if you feel unwell,
seek medical advice immediately (show the
label where possible).
HMIS (U.S.A.) Health Hazard 3 National Fire Protection
1 Flammability
1 Association (U.S.A.)
Fire Hazard
3 0 Reactivity
Health
Reactivity
0
Specific hazard
Personal Protection
E
WHMIS (Canada)
(Pictograms)
Pergolide Mesylate
DSCL (Europe)
(Pictograms)
TDG(Canada)
(Pictograms)
ADR (Europe)
(Pictograms)
Protective Equipment
Gloves.
Lab coat.
Dust respirator. Be sure to use an
approved/certified respirator or equivalent.
SECTION 16 - ADDITIONAL INFORMATION
N/A
