溴地斯的明

基本信息
毒理性
上游产品

溴地斯的明基本信息

中文名称：: 溴地斯的明

中文别名：: 溴地斯的明;
丁双吡斯的明;
吡斯的明;
Triazine catalyst;
N,N',N"-Dimethylaminopropylhexahydrotriazine;
3,3',3''-(1,3,5-triazinane-1,3,5-triyl)tris(N,N-dimethylpropan-1-amine);
1,3,5-Tris(dimethylaminopropyl)-1,3,5-hexahydrotriazine;
1,3,5-Tris-(dimethylaminopropyl)-sym-hexahydrotriazine;
1,3,5-Tris(3-dimethylaminopropyl)hexahydro-s-triazine;
4-(pentyloxy)benzoate;
4-n-Amyloxybenzoic acid;
disodium 5,5'-[(2-hydroxypropane-1,3-diyl)bis(oxy)]bis(4-oxo-4H-chromene-2-carboxylate);

英文名称：: Pyridinium,3,3'-[1,6-hexanediylbis[(methylimino)carbonyl]oxy]bis[1-methyl-, bromide (1:2)

英文别名：: Pyridinium, 3,3'-[1,6-hexanediylbis[(methylimino)carbonyl]oxy]bis[1-methyl-, bromide (1:2);
3-Hydroxy-1-methylpyridinium bromide, hexamethylenebis[methylcarbamate] (6CI,7CI);
Pyridinium, 3,3'-[1,6-hexanediylbis[(methylimino)carbonyl]oxy]bis[1-methyl-, dibromide (9CI);
Pyridinium, 3-hydroxy-1-methyl-, bromide, hexamethylenebis[methylcarbamate] (2:1) (8CI);
BC 51;
Distigmine bromide;
Distigmine dibromide;
Hexamarium;
Hexamarium bromide;
N,N'-Hexamethylenebis(3-N-methylcarbamoxy-1-methylpyridine)dibromide;
Ubretid;
Ubritil

CAS No.：: 15876-67-2

分子式：: C₂₂H₃₂N₄O₄.2Br

分子量：: 576.40

精确分子量：: 574.07903

PSA：: 66.84000

EINECS：: 240-013-0

InChI：: InChI=1/C22H32N4O4.2BrH/c1-23-13-9-11-19(17-23)29-21(27)25(3)15-7-5-6-8-16-26(4)22(28)30-20-12-10-14-24(2)18-20;;/h9-14,17-18H,5-8,15-16H2,1-4H3;2*1H/q+2;;/p-2

安全术语：: Poison by ingestion, intravenous, and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of NOx and Br−.

分子结构式：

SDS：: 查看

溴地斯的明毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UU5277000

CHEMICAL NAME :: Pyridinium, 3-hydroxy-1-methyl-, bromide, hexamethylenebis(methylcarbamate)

CAS REGISTRY NUMBER :: 15876-67-2

LAST UPDATED :: 199506

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C22-H32-N4-O4.2Br

MOLECULAR WEIGHT :: 576.40

WISWESSER LINE NOTATION :: T6KJ A1 COVN1&6N1&VO- DT6KJ A1 &E 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human - woman

DOSE/DURATION :: 900 ug/kg/3D

TOXIC EFFECTS :: Autonomic Nervous System - parasympatholytic Vascular - other changes Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: JJTOEX Japanese Journal of Toxicology. (Yakugyo Jihosha, Hokushin Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo, 101, Japan) V.1- 1988- Volume(issue)/page/year: 4,383,1991

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human - woman

DOSE/DURATION :: 700 ug/kg/7D-I

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - visual field changes Sense Organs and Special Senses (Eye) - diplopia Behavioral - hallucinations, distorted perceptions

REFERENCE :: BJCPAT British Journal of Clinical Practice. (Medical News Group, 1 Bedford St., London WC2E 9HD, UK) V.10(10)- 1956- Volume(issue)/page/year: 48,103,1994

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,68,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 740 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,349,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1080 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,349,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 740 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,68,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 10500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,68,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 310 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,349,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 900 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,349,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 300 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,68,1969