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- 2-[[4-[2-(2-氨基-4-氧代-1H-蝶啶-6-基)乙基氨基]苯甲酰基]氨基]戊烷二酸
2-[[4-[2-(2-氨基-4-氧代-1H-蝶啶-6-基)乙基氨基]苯甲酰基]氨基]戊烷二酸
2-[[4-[2-(2-氨基-4-氧代-1H-蝶啶-6-基)乙基氨基]苯甲酰基]氨基]戊烷二酸 基本信息
- 中文名称：
- 2-[[4-[2-(2-氨基-4-氧代-1H-蝶啶-6-基)乙基氨基]苯甲酰基]氨基]戊烷二酸
- 中文别名：
-
- 英文名称：
- L-Glutamic acid,N-[4-[[2-(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)ethyl]amino]benzoyl]- (9CI)
- 英文别名：
- Homofolic acid;
N-{4-[2-(2-amino-4-oxo-3,4-dihydro-pteridin-6-yl)-ethylamino]-benzoyl}-glutamic acid;
2-Glutamic acid,N-(4-(2-(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)ethylamino)benzoyl)-(9ci);
L-Glutamic acid,N-(4-((2-(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)ethyl)amino)benzoyl)-(9ci);
Glutamic acid,N-(p-((2-(2-amino-4-hydroxy-6-pteridinyl)ethyl)amino)benzoyl);
N-<4-(<2-(2-Amino-4-hydroxy-6-pteridinyl)-aethyl>-amino)-benzoyl-L-glutaminsaeure;
N-[p-[[2-(2-Amino-4-hydroxy-6-pteridinyl)ethyl]amino]benzoyl]-L-glutamic acid;
Homofolsaeure;
Homofolate
- CAS No.：
- 3566-25-4
- 分 子 式：
- C20H21N7O6
- 分 子 量：
- 455.48
- 精确分子量：
- 455.15500
- PSA：
- 213.28000
- InChI：
- The Key: QXARTGUOGAZGKO-UHFFFAOYSA-N
- 安全术语：
- An experimental teratogen. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
- 分子结构式：
-
- SDS：
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2-[[4-[2-(2-氨基-4-氧代-1H-蝶啶-6-基)乙基氨基]苯甲酰基]氨基]戊烷二酸 物化性质
2-[[4-[2-(2-氨基-4-氧代-1H-蝶啶-6-基)乙基氨基]苯甲酰基]氨基]戊烷二酸 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MA0601000
- CHEMICAL NAME :
- Glutamic acid,
N-(p-((2-(2-amino-4-hydroxy-6-pteridinyl)ethyl)amino)
benzoyl)-
- CAS REGISTRY NUMBER :
- 3566-25-4
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C20-H21-N7-O6
- MOLECULAR WEIGHT :
- 455.48
- WISWESSER LINE NOTATION :
- T66 BN DN GN JNJ CZ EQ H2MR DVMYVQ2VQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 12800 ug/kg
- SEX/DURATION :
- female 8-9 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - stillbirth
Reproductive - Effects on Newborn - live birth index (measured after birth)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 400 mg/kg
- SEX/DURATION :
- female 8 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- REFERENCE :
- LIFSAK Life Sciences. (Pergamon Press Inc., Maxwell House, Fairview Park,
Elmsford, NY 10523) V.1-8, 1962-69; V.14- 1974- Volume(issue)/page/year:
14,1541,1974
