拌种灵

  • 基本信息
  • 制备方法及用途
  • 物化性质
  • 安全信息
  • 毒理性
  • MSDS
  • 海关数据

拌种灵 基本信息

中文名称:
拌种灵 
中文别名:
拌种灵;
2-氨基-4-甲基-噻唑-5-甲酰苯胺 
英文名称:
5-Thiazolecarboxamide,2-amino-4-methyl-N-phenyl-
英文别名:
amicarthiazol;
2-Amino-4-methyl-1,3-thiazole-5-carboxanilide 2-Amino-4-methyl-N-phenyl-5-thiazolecarboxamide;
2-amino-4-methyl-N-phenyl-5-thiazolecarboxamide;
2-amino-4-methyl-N-phenyl-1,3-thiazole-5-carboxamide;
2-Amino-4-methyl-N-phenyl-1,3-thiazole-5-carboxamide;
2-Amino-4-Methyl-N-Phenyl-5-Thiazolecarboxamide;
2-amino-4-methyl-1,3-thiazole-5-carboxanilide 
CAS No.:
21452-14-2
分 子 式:
C11H11N3OS
分 子 量:
0
精确分子量:
233.06200
PSA:
100.47000
InChI:
The Key: CACOMUHPQMDEJQ-UHFFFAOYSA-N
风险术语:
22-36/37/38
分子结构式:
SDS:
查看

拌种灵 制备方法及用途

合成制备方法

工艺过程按下列步骤进行:(1)α-氯代乙酰乙酰苯胺的合成(氯化)将乙酰乙酰苯胺和甲苯加入反应器,搅拌下在20℃左右滴加氯化硫酰,控制反应温度在25-30℃,半小时滴加完毕,继续保温反应2.5h,即α-氯代乙酰乙酰苯胺的甲苯悬浮液。(2)拌种灵合成(缩合):将第一步得到的甲苯悬浮液,加入硫脲和水,升温至回流,反应半小时。反应毕,静置分层,上层为甲苯层,可继续循环套用,下层为拌种灵盐酸盐水溶液。分出水层,并加水稀释,搅拌下加氨水中和至pH8过滤生成的沉淀用水洗至近中性,烘干得白色粉末状产品,含量约96%。对乙酰乙酰苯胺的收率约8%。原料消耗定额:乙酰乙酰苯胺(>98)880kg/t、氯化硫酰(100%)700kg/t、硫脲(>95%)410kg/t、氨水(25%)520kg/t。

用途

内吸性杀菌剂,兼有植物激素的作用。 以0.25%浸种防治红麻炭疽病,连续两年防治效果高达100%,拌种效果也在98%以上;防治禾谷类黑穗病、棉花角斑病效果相当于赛力散和两力生。对水稻白叶枯病及花生锈病也有防治效果。该品主要使用途径为拌种或浸种,一般使用量为种子重量的0.3-0.5%。

拌种灵 物化性质

密度:
1.375g/cm3
沸点:
354.5ºC at 760mmHg
闪点:
168.2ºC
折射率:
1.711
蒸汽压:
3.34E-05mmHg at 25°C
存储条件/存储方法:
库房通风低温干燥
稳定性相关:

在碱性介质中易分解。

其它信息:

1.性状:白色结晶粉末。

2.熔点:222-224℃,275-285℃分解,

3.溶解度:易溶于DMF,难溶于水及一般有机溶剂。

拌种灵 安全信息

海关代码:
2934100017

拌种灵 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XJ2700000
CHEMICAL NAME :
Thiazole, 2-amino-4-methyl-5-phenylcarbamoyl-
CAS REGISTRY NUMBER :
21452-14-2
LAST UPDATED :
199706
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C11-H11-N3-O-S
MOLECULAR WEIGHT :
233.31
WISWESSER LINE NOTATION :
T5N CSJ BZ DVMR E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1410 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C272,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
141 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971 Volume(issue)/page/year: -,419,1971
毒理学数据:

口服-大鼠LD50: 1410 毫克/公斤

拌种灵 MSDS


SECTION 1: Identification of the substance/mixture and of the company/undertaking
  Product identifiers
    Product name        : Amicarthiazol    
    : Fluka
    REACH No.        : A registration number is not available for this substance as the substance    
    or its uses are exempted from registration, the annual tonnage does not
    require a registration or the registration is envisaged for a later
    registration deadline.
    CAS-No.        : 21452-14-2    
  

SECTION 2: Hazards identification
  Classification of the substance or mixture
  Classification according to Regulation (EC) No 1272/2008
    Acute toxicity, Oral (Category 4), H302
    Skin irritation (Category 2), H315
    Eye irritation (Category 2), H319
    Specific target organ toxicity - single exposure (Category 3), H335
    For the full text of the H-Statements mentioned in this Section, see Section 16.
  Classification according to EU Directives 67/548/EEC or 1999/45/EC
    Xn Harmful        R22, R36/37/38    
    For the full text of the R-phrases mentioned in this Section, see Section 16.
  Label elements
  Labelling according Regulation (EC) No 1272/2008
    Pictogram
    Signal word        Warning    
    Hazard statement(s)
    Harmful if swallowed.
    Causes skin irritation.
    Causes serious eye irritation.
    May cause respiratory irritation.
    Precautionary statement(s)
    Avoid breathing dust.
    P305 + P351 + P338        IF IN EYES: Rinse cautiously with water for several minutes. Remove    
    contact lenses, if present and easy to do. Continue rinsing.
    Supplemental Hazard        none    
    Statements
  Other hazards - none

SECTION 3: Composition/information on ingredients
  Substances
    Formula        : C11H11N3OS    
    Molecular Weight        : 233,29 g/mol    
    CAS-No.        : 21452-14-2    
  Hazardous ingredients according to Regulation (EC) No 1272/2008
    Component        Classification        Concentration    
  2-Amino-4-methyl-1,3-thiazole-5-carboxanilide // 2-Amino-4-methyl-N-phenyl-5-
  thiazolecarboxamide
    CAS-No.        21452-14-2        Acute Tox. 4; Skin Irrit. 2; Eye        <= 100 %    
    Irrit. 2; STOT SE 3; H302,
    H315, H319, H335
    For the full text of the H-Statements and R-Phrases mentioned in this Section, see Section 16

SECTION 4: First aid measures
  Description of first aid measures
  General advice
    Consult a physician. Show this safety data sheet to the doctor in attendance.
  If inhaled
    If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
  In case of skin contact
    Wash off with soap and plenty of water. Consult a physician.
  In case of eye contact
    Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
  If swallowed
    Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
  Most important symptoms and effects, both acute and delayed
    The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
    section 11
  Indication of any immediate medical attention and special treatment needed
    no data available

SECTION 5: Firefighting measures
  Extinguishing media
  Suitable extinguishing media
    Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
  Special hazards arising from the substance or mixture
    Carbon oxides, nitrogen oxides (NOx), Sulphur oxides
  Advice for firefighters
    Wear self contained breathing apparatus for fire fighting if necessary.
  Further information
    no data available

SECTION 6: Accidental release measures
  Personal precautions, protective equipment and emergency procedures
    Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure
    adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
    For personal protection see section 8.
  Environmental precautions
    Do not let product enter drains.
  Methods and materials for containment and cleaning up
    Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed
    containers for disposal.
  Reference to other sections
    For disposal see section 13.

SECTION 7: Handling and storage
  Precautions for safe handling
    Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
    Provide appropriate exhaust ventilation at places where dust is formed.
    For precautions see section 2.2.
  Conditions for safe storage, including any incompatibilities
    Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
  Specific end use(s)
    Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection
  Control parameters
  Components with workplace control parameters
  Exposure controls
  Appropriate engineering controls
    Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and
    at the end of workday.
  Personal protective equipment
  Eye/face protection
    Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested
    and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
  Skin protection
    Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
    (without touching glove's outer surface) to avoid skin contact with this product. Dispose of
    contaminated gloves after use in accordance with applicable laws and good laboratory practices.
    Wash and dry hands.
    The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
    the standard EN 374 derived from it.
  Body Protection
    Complete suit protecting against chemicals, The type of protective equipment must be selected
    according to the concentration and amount of the dangerous substance at the specific workplace.
  Respiratory protection
    For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator.For higher
    level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges.
    Use respirators and components tested and approved under appropriate government standards
    such as NIOSH (US) or CEN (EU).
  Control of environmental exposure
    Do not let product enter drains.

SECTION 9: Physical and chemical properties
  Information on basic physical and chemical properties
    a) Appearance        Form: powder    
    Colour: light yellow
    b) Odour        odourless    
    c) Odour Threshold        no data available    
    d) pH        no data available    
    e) Melting point/freezing        no data available    
    point
    f) Initial boiling point and no data available
    boiling range
    g) Flash point        no data available    
    h) Evapouration rate        no data available    
    i) Flammability (solid, gas) no data available
    j) Upper/lower        no data available    
    flammability or
    explosive limits
    k) Vapour pressure        no data available    
    l) Vapour density        no data available    
    m) Relative density        no data available    
    n) Water solubility        no data available    
    o) Partition coefficient: n- log Pow: 1,88
    octanol/water
    p) Auto-ignition        no data available    
    temperature
    q) Decomposition        no data available    
    temperature
    r) Viscosity        no data available    
    s) Explosive properties        no data available    
    t) Oxidizing properties        no data available    
  Other safety information
    no data available

SECTION 10: Stability and reactivity
  Reactivity
    no data available
  Chemical stability
    Stable under recommended storage conditions.
  Possibility of hazardous reactions
    no data available
  Conditions to avoid
    no data available
  Incompatible materials
    Strong oxidizing agents
  Hazardous decomposition products
    Other decomposition products - no data available
    In the event of fire: see section 5

SECTION 11: Toxicological information
  Information on toxicological effects
  Acute toxicity
    LD50 Oral Oral - rat - 1.410 mg/kg
  Skin corrosion/irritation
    no data available
  Serious eye damage/eye irritation
    no data available
  Respiratory or skin sensitisation
    no data available
  Germ cell mutagenicity
    no data available
  Carcinogenicity
    IARC:        No component of this product present at levels greater than or equal to 0.1% is identified as    
    probable, possible or confirmed human carcinogen by IARC.
  Reproductive toxicity
    no data available
  Specific target organ toxicity - single exposure
    no data available
  Specific target organ toxicity - repeated exposure
    no data available
  Aspiration hazard
    no data available
  Additional Information
    RTECS: XJ2700000
    To the best of our knowledge, the chemical, physical, and toxicological properties have not been
    thoroughly investigated.

SECTION 12: Ecological information
  Toxicity
    no data available
  Persistence and degradability
    no data available
  Bioaccumulative potential
    no data available
  Mobility in soil
    no data available
  Results of PBT and vPvB assessment
    PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
  Other adverse effects
    no data available

SECTION 13: Disposal considerations
  Waste treatment methods
  Product
    Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material
    with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
  Contaminated packaging
    Dispose of as unused product.

SECTION 14: Transport information
  UN number
    ADR/RID: -        IMDG: -        IATA: -    
  UN proper shipping name
    ADR/RID: Not dangerous goods
    IMDG: Not dangerous goods
    IATA:        Not dangerous goods    
  Transport hazard class(es)
    ADR/RID: -        IMDG: -        IATA: -    
  Packaging group
    ADR/RID: -        IMDG: -        IATA: -    
  Environmental hazards
    ADR/RID: no        IMDG Marine pollutant: no        IATA: no    
  Special precautions for user
    no data available

SECTION 15: Regulatory information
    This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
  Safety, health and environmental regulations/legislation specific for the substance or mixture
    no data available
  Chemical Safety Assessment
  Further information
    only.
    The above information is believed to be correct but does not purport to be all inclusive and shall be
    used only as a guide. The information in this document is based on the present state of our knowledge
    and is applicable to the product with regard to appropriate safety precautions. It does not represent any


SECTION 16 - ADDITIONAL INFORMATION
N/A

拌种灵 海关数据

中国海关编码:2934100017

概述:
2934100017 辛噻酮,拌种灵。监管条件:S(进出口农药登记证明)。增值税率:17.0%。退税率:9.0%。最低关税:6.5%。普通关税:20.0%
申报要素:
品名, 成分含量, 用途
监管条件:
S.进出口农药登记证明
摘要/Summary:
2934100017 2-octylisothiazol-3(2h)-one。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%

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