Section 1 - Chemical Product
(+)-Aphidicolin Material Safety Data Sheet
8,11a-Methano-11aH-cyclohepta(a)naphthalene-4,9-dimethanol; tetradecahydro-3,9-dihydroxy 4,11b-dimethyl-,(3R-(3-alpha,4-alpha, 4a-alpha, 6a-beta, 8-beta, 9-beta, 11a-beta, 11beta))-
MSDS Name:(+)-Aphidicolin Material Safety Data Sheet
Synonym:8,11a-Methano-11aH-cyclohepta(a)naphthalene-4,9-dimethanol; tetradecahydro-3,9-dihydroxy 4,11b-dimethyl-,(3R-(3-alpha,4-alpha, 4a-alpha, 6a-beta, 8-beta, 9-beta, 11a-beta, 11beta))-
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Hazard Symbols: None Listed.
Risk Phrases: None Listed.
Section 3 - HAZARDS IDENTIFICATION
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
May cause eye irritation.
May cause skin irritation.
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
No information found.
Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Wash area with soap and water. Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Section 7 - HANDLING and STORAGE
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep refrigerated. (Store below 4C/39F.)
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 38966-21-1: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Wear appropriate protective gloves to prevent skin exposure.
Wear appropriate protective clothing to prevent skin exposure.
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Solid
Odor: none reported
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Solubility in water:
Molecular Formula: C28H26N4O3
Molecular Weight: 466.5
Section 10 - STABILITY AND REACTIVITY
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, electrical sparks.
Incompatibilities with Other Materials:
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
CAS# 38966-21-1: PB9185000 LD50/LC50:
(+)-Aphidicolin - Not listed by ACGIH, IARC, or NTP.
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Section 13 - DISPOSAL CONSIDERATIONS
Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.
Section 14 - TRANSPORT INFORMATION
No information available.
No information available.
No information available.
Section 15 - REGULATORY INFORMATION
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 38966-21-1: No information available.
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 38966-21-1 is not listed on Canada's Ingredient Disclosure List.
CAS# 38966-21-1 is not listed on the TSCA inventory.
It is for research and development use only.
SECTION 16 - ADDITIONAL INFORMATION