全缘千里光碱

密度：

1.25g/cm3

沸点：

563.7ºC at 760 mmHg

闪点：

294.7ºC

折射率：

1.57

蒸汽压：

4.68E-15mmHg at 25°C

包装等级：

III

风险类别：

6.1(b)

CHEMICAL IDENTIFICATION

RTECS NUMBER :

NM9080000

CHEMICAL NAME :

Integerrimine

CAS REGISTRY NUMBER :

480-79-5

LAST UPDATED :

199603

DATA ITEMS CITED :

6

MOLECULAR FORMULA :

C18-H25-N-O5

MOLECULAR WEIGHT :

335.44

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

250 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

75 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

78 mg/kg

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory stimulation

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

300 mg/kg/20D-I

TOXIC EFFECTS :

Related to Chronic Data - death

MUTATION DATA

TEST SYSTEM :

Rodent - mouse

DOSE/DURATION :

18750 ug/kg

REFERENCE :

MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 241,297,1990