盐酸美法仑

基本信息
物化性质
安全信息
毒理性
海关数据

盐酸美法仑基本信息

中文名称：: 盐酸美法仑

中文别名：: 左旋苯丙氨酸氮芥盐酸盐;
盐酸美法仑;
(S)-3-[4-[双(2-氯乙基)氨基]苯基]丙氨酸盐酸盐

英文名称：: Melphalan hydrochloride

英文别名：: Melphalan hydrochloride;
4-[Bis(2-chloroethyl)amino]-L-phenylalanine hydrochloride;
Melphalan Hydrochloride,Phenylalanine, 4-[bis(2-chloroethyl)amino]-, hydrochloride (1:1)

CAS No.：: 3223-07-2

分子式：: C13H19Cl3N2O2

分子量：: 341.66100

精确分子量：: 340.05100

PSA：: 66.56000

InChI：: InChI=1/C13H18Cl2N2O2.ClH/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19;/h1-4,12H,5-9,16H2,(H,18,19);1H/t12-;/m0./s1

分子结构式：

SDS：: 查看

盐酸美法仑物化性质

沸点：: 473.1ºC at 760mmHg
闪点：: 239.9ºC
存储条件/存储方法：: 库房通风低温干燥,与食品原料分开存放

盐酸美法仑安全信息

海关代码：: 2922499990

盐酸美法仑毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AY4025000

CHEMICAL NAME :: Alanine, 3-(p-(bis(2-chloroethyl)amino)phenyl)-, monohydrochloride, L-

CAS REGISTRY NUMBER :: 3223-07-2

LAST UPDATED :: 199706

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C13-H18-Cl2-N2-O2.Cl-H

MOLECULAR WEIGHT :: 341.69

WISWESSER LINE NOTATION :: QVYZ1R DN2G2G &GH -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human

DOSE/DURATION :: 1200 ug/kg/5D-I

TOXIC EFFECTS :: Gastrointestinal - nausea or vomiting

REFERENCE :: CCROBU Cancer Chemotherapy Reports, Part 1. (Washington, DC) V.52(6)-59, 1968-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 57,369,1973

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 430 ug/kg

TOXIC EFFECTS :: Blood - leukopenia Blood - thrombocytopenia Blood - other changes

REFERENCE :: CCSUBJ Cancer Chemotherapy Reports, Part 2. (Washington, DC) V.1-5, 1964-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 2,201,1965

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Primate - monkey

DOSE/DURATION :: 430 ug/kg

TOXIC EFFECTS :: Blood - leukopenia Blood - agranulocytosis Blood - other changes

REFERENCE :: CCSUBJ Cancer Chemotherapy Reports, Part 2. (Washington, DC) V.1-5, 1964-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 2,201,1965 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1300 ug/kg/4W

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors

REFERENCE :: JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 36,915,1966

盐酸美法仑海关数据

中国海关编码：2922499990

概述：: 2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%
申报要素：: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
监管条件：: A.入境货物通关单B.出境货物通关单
检验检疫：: P.进境动植物、动植物产品检疫Q.出境动植物、动植物产品检疫R.进口食品卫生监督检验S.出口食品卫生监督检验M.进口商品检验N.出口商品检验
摘要/Summary：: HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%