N-BOC-AMINO-(4-N-FMOC-PIPERIDINYL) CARBOXYLIC ACID

  • 基本信息
  • 物化性质
  • 安全信息
  • 毒理性
  • MSDS
  • 海关数据
  • 结构与计算化学

N-BOC-AMINO-(4-N-FMOC-PIPERIDINYL) CARBOXYLIC ACID 基本信息

中文名称:
N-BOC-AMINO-(4-N-FMOC-PIPERIDINYL) CARBOXYLIC ACID 
中文别名:
1-Fmoc-4-(Boc-氨基)哌啶-4-甲酸;
4-(叔丁氧羰基氨基)-1-芴甲氧羰基哌啶-4-羧酸 
英文名称:
N-BOC-AMINO-(4-N-FMOC-PIPERIDINYL) CARBOXYLIC ACID
英文别名:
4-(Boc-amino)-1-Fmoc-piperdine-4-carboxylic Acid;
1-(9H-fluoren-9-ylmethoxycarbonyl)-4-[(2-methylpropan-2-yl)oxycarbonylamino]piperidine-4-carboxylate;
N-BOC-Amino-(4-N-FMOC-piperidinyl)carboxylic acid 
CAS No.:
368866-07-3
分 子 式:
C26H30N2O6
分 子 量:
466.53
精确分子量:
466.21000
PSA:
105.17000
MDL:
MFCD02683117
InChI:
The Key: SHJZHFAOEGNFGY-UHFFFAOYSA-N
风险术语:
36/37/38
分子结构式:
SDS:
查看

N-BOC-AMINO-(4-N-FMOC-PIPERIDINYL) CARBOXYLIC ACID 物化性质

沸点:
658.1ºC at 760mmHg
闪点:
351.8ºC
存储条件/存储方法:

 

密闭于-20ºC阴凉干燥环境中
稳定性相关:

 

遵照规定使用和储存则不会分解。

其它信息:

1.      性状:白色粉末

2.      密度(g/mL,25/4):无可用3.      相对蒸汽密度(g/mL,空气=1):无可用4.      熔点(ºC):无可用5.      沸点(ºC,常压):无可用6.      沸点(ºC,5.2kPa):无可用7.      折射率:无可用8.      闪点(ºC):无可用9.      比旋光度(º):无可用10.   自燃点或引燃温度(ºC):无可用11.   蒸气压(kPa,25ºC):无可用12.   饱和蒸气压(kPa,60ºC):无可用13.   燃烧热(KJ/mol):无可用14.   临界温度(ºC):无可用15.   临界压力(KPa):无可用16.   油水(辛醇/水)分配系数的对数值:无可用17.   爆炸上限(%,V/V):无可用18.   爆炸下限(%,V/V):无可用19.   溶解性:无可用

N-BOC-AMINO-(4-N-FMOC-PIPERIDINYL) CARBOXYLIC ACID 安全信息

海关代码:
2922499990
危险类别码:
R36/37/38
安全说明:
37/39-26
危险标志:
Xi

N-BOC-AMINO-(4-N-FMOC-PIPERIDINYL) CARBOXYLIC ACID 毒理性

生态数据:

 

该物质对环境可能有危害,对水体应给予特别注意。

N-BOC-AMINO-(4-N-FMOC-PIPERIDINYL) CARBOXYLIC ACID MSDS

Name: N-BOC-AMINO-(4-N-FMOC-PIPERIDINYL)CARBOXYLIC ACID Material Safety Data Sheet
Synonym: N-(tert-Butoxycarbonyl)-amino-(4-N-FMOC-piperidinyl)carboxylic acid.
CAS: 368866-07-3
Section 1 - Chemical Product MSDS Name: N-BOC-AMINO-(4-N-FMOC-PIPERIDINYL)CARBOXYLIC ACID Material Safety Data Sheet
Synonym: N-(tert-Butoxycarbonyl)-amino-(4-N-FMOC-piperidinyl)carboxylic acid.
SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
368866-07-3 N-BOC-Amino-(4-N-FMOC-piperidinyl)carb ca. 100 unlisted
+++++
Hazard Symbols: XI
SECTION 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Irritating to eyes, respiratory system and skin. Potential Health Effects
Eye:
Causes eye irritation. May cause chemical conjunctivitis.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled. Can produce delayed pulmonary edema.
Chronic:
No information found.
SECTION 4 - FIRST AID MEASURES
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:
Treat symptomatically and supportively.
SECTION 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.
SECTION 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation.
SECTION 7 - HANDLING and STORAGE
Handling:
Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse.
Storage:
Store in a cool, dry place. Store in a tightly closed container.
SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 368866-07-3: Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Solid
Color: white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C26H30N2O6
Molecular Weight: 466.53
SECTION 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Dust generation.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported
SECTION 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 368866-07-3 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
N-BOC-Amino-(4-N-FMOC-piperidinyl)carboxylic acid - Not listed by ACGIH, IARC, or NTP.
SECTION 12 - ECOLOGICAL INFORMATION
SECTION 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations.
SECTION 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material.
SECTION 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 368866-07-3: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 368866-07-3 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 368866-07-3 is not listed on the TSCA inventory. It is for research and development use only.
SECTION 16 - ADDITIONAL INFORMATION
MSDS Creation Date: 3/20/2003 Revision #1 Date: 6/23/2003 The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no way shall the company be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if the company has been advised of the possibility of such damages.

SECTION 16 - ADDITIONAL INFORMATION
N/A

N-BOC-AMINO-(4-N-FMOC-PIPERIDINYL) CARBOXYLIC ACID 海关数据

中国海关编码:2922499990

概述:
2922499990 其他氨基酸及其酯及它们的盐(含有一种以上含氧基的除外). 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%
申报要素:
品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
监管条件:
A.入境货物通关单B.出境货物通关单
检验检疫:
P.进境动植物、动植物产品检疫Q.出境动植物、动植物产品检疫R.进口食品卫生监督检验S.出口食品卫生监督检验M.进口商品检验N.出口商品检验
摘要/Summary:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

N-BOC-AMINO-(4-N-FMOC-PIPERIDINYL) CARBOXYLIC ACID 分子结构与计算化学数据

分子结构数据

1摩尔折射率:无可用

2、  摩尔体积(cm3/mol):无可用       

3、  等张比容(90.2K):无可用

4、  表面张力(dyne/cm):无可用

5、  极化率:无可用

计算化学数据

1.疏水参数计算参考值(XlogP):4.5

2.氢键供体数量:1

3.氢键受体数量:6

4.可旋转化学键数量:6

5.互变异构体数量:2

6.拓扑分子极性表面积108

7.重原子数量:34

8.表面电荷:-1

9.复杂度:742

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

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