偏苯三酸酐

外观与性状：

白色至灰白色片

密度：

1.54

熔点：

163-166 °C(lit.)

沸点：

390 °C

闪点：

227 °C

水溶解性：

DECOMPOSES

折射率：

1.662

蒸汽密度：

6.6 (vs air)

存储条件/存储方法：

密封干燥阴凉处，并远离强碱、水源、湿气

稳定性相关：

 分子内有酸酐与羧基，性活泼，与水作用生成酸，与醇酯化生成酯。用于制聚酯树脂、聚酰亚胺树脂、耐高温电气绝缘材料、聚氯乙烯增塑剂等。避免与碱、氧化物、水分/潮湿接触。

其它信息：

1. 性状：白色至微黄色针状晶体
2. 密度（g/mL,0℃）：1.68
3. 熔点（ºC）：167
4. 沸点（ºC,常压）：390
5. 沸点（ºC，1.87kpa）：240～245
6. 闪点（ºC）：222
7. 自燃点或引燃温度（ºC）：227
8. 溶解性：溶于热水及丙酮、2-丁酮、二甲基甲酰胺、乙酸乙酯、环己酮。溶于无水乙醇

9.相对密度（20℃，4℃）：1.55

海关代码：

29173980

WGK_Germany：

1
德国有关水污染物质的分类清单

危险类别码：

R37;R41;R42/43

安全说明：

S22-S26-S36/37/39

RTECS号：

DC2050000

安全标志：

S22:不要吸入粉尘。
S26:万一接触眼睛，立即使用大量清水冲洗并送医诊治。
:

危险标志：

Xn:Harmful

CHEMICAL IDENTIFICATION

RTECS NUMBER :

DC2050000

CHEMICAL NAME :

1,2,4-Benzenetricarboxylic acid 1,2-anhydride

CAS REGISTRY NUMBER :

552-30-7

BEILSTEIN REFERENCE NO. :

0009394

LAST UPDATED :

199712

DATA ITEMS CITED :

25

MOLECULAR FORMULA :

C9-H4-O5

MOLECULAR WEIGHT :

192.13

WISWESSER LINE NOTATION :

T56 BVOVJ GVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LC - Lethal concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

>7400 mg/m3/4H

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

85INA8 "Documentation of the Threshold Limit Values and Biological Exposure Indices," 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986 Volume(issue)/page/year: 6,1642,1991

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

1900 mg/kg

TOXIC EFFECTS :

Lungs, Thorax, or Respiration - dyspnea

REFERENCE :

GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 18(7),57,1974

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

5600 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

85INA8 "Documentation of the Threshold Limit Values and Biological Exposure Indices," 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986 Volume(issue)/page/year: 6,1642,1991 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

258 ug/m3/6H/10D-I

REFERENCE :

TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 87,67,1987 *** REVIEWS *** ACGIH TLV-CL 0.04 mg/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 TOXICOLOGY REVIEW BPCT** Progress Report from the Environmental Protection Agency to NIOSH on Benzenepolycarboxylates, 1974 Volume(issue)/page/year: -,183,1974 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 0.005 ppm (0.04 mg/m3) JAN 1993 OEL-BELGIUM:TWA 0.005 ppm (0.059 mg/m3) JAN 1993 OEL-DENMARK:TWA 0.1 mg/m3 JAN 1993 OEL-FRANCE:TWA 0.005 ppm (0.04 mg/m3) JAN 1993 OEL-GERMANY:TWA 0.005 ppm (0.04 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 0.004 ppm (0.04 mg/m3) JAN 1993 OEL-RUSSIA:STEL 0.1 mg/m3 JAN 1993 OEL-SWEDEN:TWA 0.005 ppm (0.04 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 0.005 ppm (0.04 mg/m3);STEL 0.01 ppm JAN 1993 OEL-UNITED KINGDOM:TWA 0.04 mg/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO TRIMELLITIC ANHYDRIDE-air:10H TWA 0.005 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83588 No. of Facilities: 196 (estimated) No. of Industries: 8 No. of Occupations: 31 No. of Employees: 11308 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83588 No. of Facilities: 358 (estimated) No. of Industries: 9 No. of Occupations: 13 No. of Employees: 17745 (estimated) No. of Female Employees: 5236 (estimated)

毒理学数据：

急性毒性：大鼠吸入LC：>7400 mg/m3/4H；

小鼠经口LD50：1900mg/kg，肺、胸或呼吸困难；

小鼠经静脉注射：196mg/kg，行为-改变睡眠时间（包括变化的翻正反射）。

兔子经口LD50：5600mg/kg；

刺激皮肤和黏膜，可引起过敏及变态反应等障碍。空气中最高允许浓度1mg/m3

生态数据：

对水是稍微危害的，不要让未稀释或大量的产品接触地下水、水道或者污水系统。

分子结构数据

1、   摩尔折射率：42.61

2、   摩尔体积（cm³/mol）：115.0

3、   等张比容（90.2K）：343.5

4、   表面张力（dyne/cm）：79.4

5、   极化率（10^-24cm³）：16.89

计算化学数据

1.疏水参数计算参考值（XlogP）:0.8

2.氢键供体数量:1

3.氢键受体数量:5

4.可旋转化学键数量:1

5.互变异构体数量:无

6.拓扑分子极性表面积80.7

7.重原子数量:14

8.表面电荷:0

9.复杂度:308

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

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  4-苯三酸酐红外图谱(IR1)