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去痛定 基本信息
- 中文名称：
- 去痛定
- 中文别名：
- 去痛定;
匹米诺定
- 英文名称：
- Piminodine
- 英文别名：
- Piminodine;
Cimadon;
Anopridine;
Dea no. 9730;
Alvodine;
Einecs 236-817-6
- CAS No.：
- 13495-09-5
- 分 子 式：
- C23H30N2O2
- 分 子 量：
- 0
- 精确分子量：
- 366.23100
- PSA：
- 41.57000
- EINECS：
- 236-817-6
- InChI：
- The Key: PXXKIYPSXYFATG-UHFFFAOYSA-N
- 分子结构式：
-
- SDS：
- 查看
去痛定 物化性质
- 密度：
- 1.103g/cm3
- 沸点：
- 515.2ºC at 760 mmHg
- 闪点：
- 265.4ºC
- 折射率：
- 1.574
- 蒸汽压：
- 1E-10mmHg at 25°C
去痛定 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TM6408250
- CHEMICAL NAME :
- 4-Piperidinecarboxylic acid,
4-phenyl-1-(3-(phenylamino)propyl)-, ethyl ester
- CAS REGISTRY NUMBER :
- 13495-09-5
- BEILSTEIN REFERENCE NO. :
- 0334632
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C23-H30-N2-O2
- MOLECULAR WEIGHT :
- 366.55
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 228 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
3,358,1961
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 39 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
Gastrointestinal - changes in structure or function of salivary glands
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
3,358,1961
