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盐酸甲氧安非他明 基本信息
- 中文名称：
- 盐酸甲氧安非他明
- 中文别名：
- 盐酸甲氧安非他明
- 英文名称：
- PMA HYDROCHLORIDE
- 英文别名：
- PMA HYDROCHLORIDE;
dl-4-methoxyamphetaminehydrochloride;
P-METHOXYAMPHETAMINE HYDROCHLORIDE
- CAS No.：
- 52740-56-4
- 分 子 式：
- C10H16ClNO
- 分 子 量：
- 201.69
- 精确分子量：
- 201.09200
- PSA：
- 35.25000
- EINECS：
- 200-659-6
- 分子结构式：
-
- SDS：
- 查看
盐酸甲氧安非他明 物化性质
- 沸点：
- 258.2ºC at 760 mmHg
- 闪点：
- 11ºC
盐酸甲氧安非他明 安全信息
- 危险类别码：
- 22-39/23/24/25-23/24/25-11
- 安全说明：
- 36/37/39-45-36/37-16
- 危险标志：
- Xn,T,F
盐酸甲氧安非他明 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SH8125000
- CHEMICAL NAME :
- Phenethylamine, 4-methoxy-alpha-methyl-,
hydrochloride, DL-
- CAS REGISTRY NUMBER :
- 52740-56-4
- LAST UPDATED :
- 199106
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C10-H15-N-O.Cl-H
- MOLECULAR WEIGHT :
- 201.72
- WISWESSER LINE NOTATION :
- ZY1&1R DO1 &GH -DL
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 46 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - muscle weakness
Behavioral - ataxia
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
45,49,1978
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 284 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - ataxia
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
45,49,1978
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 40 mg/kg
- TOXIC EFFECTS :
- Vascular - BP elevation not characterized in autonomic section
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
20037) V.6- 1963- Volume(issue)/page/year: 8,100,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 49 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified
Behavioral - tremor
Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
45,49,1978
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 7 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor
Behavioral - excitement
Behavioral - ataxia
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
45,49,1978
