呋喃洛芬

密度：

1.23g/cm3

沸点：

449.4ºC at 760 mmHg

闪点：

225.6ºC

折射率：

1.627

CHEMICAL IDENTIFICATION

RTECS NUMBER :

DF6424000

CHEMICAL NAME :

7-Benzofuranacetic acid, alpha-methyl-3-phenyl-, (+-)-

CAS REGISTRY NUMBER :

67700-30-5

LAST UPDATED :

199109

DATA ITEMS CITED :

3

MOLECULAR FORMULA :

C17-H14-O3

MOLECULAR WEIGHT :

266.31

WISWESSER LINE NOTATION :

T56 BOJ DR& IY1&VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Human

DOSE/DURATION :

5 mg/kg

TOXIC EFFECTS :

Gastrointestinal - other changes

REFERENCE :

JCPCBR Journal of Clinical Pharmacology. (Hall Assoc., PO Box 482, Stamford, CT 06904) V.13- 1973- Volume(issue)/page/year: 16,473,1976

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

950 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 214,240,1975

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

>1400 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 214,240,1975