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克拉唑仑 基本信息
- 中文名称：
- 克拉唑仑
- 中文别名：
- 克拉唑仑
- 英文名称：
- Clazolam
- 英文别名：
- ISOQUINAZEPON;
5,9,10,14b-Tetrahydro-2-chloro-5-methylisoquino[2,1-d][1,4]benzodiazepin-6(7H)-one;
41-123;
Clazolam;
2-Chloro-5-methyl-5,9,10,14B-tetrahydroisoquino[2,1-D][1,4]benzodiazepin-6(7H)-one;
2-chloro-5-methyl-5,9,10,14b-tetrahydro-benzo[5,6][1,4]diazepino[7,1-a]isoquinolin-6-one;
d,l-2-Chlor-5-methyl-5,9,10,14b-tetrahydro-isochino<2,1-d><1,4>benzodiazepin-6(7H)-on;
2-Chloro-5,9,10,14b-tetrahydro-5-methylisoquino[2,1-d][1,4]benzodiazepin-6(7H)-one
- CAS No.：
- 7492-29-7
- 分 子 式：
- C18H17ClN2O
- 分 子 量：
- 0
- 精确分子量：
- 312.10300
- PSA：
- 23.55000
- InChI：
- The Key: YAQKGZXXQNKEET-UHFFFAOYSA-N
- 分子结构式：
-
- SDS：
- 查看
克拉唑仑 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NW6710000
- CHEMICAL NAME :
- Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one,
5,9,10,14b-tetrahydro-2-chloro-5-methyl-
- CAS REGISTRY NUMBER :
- 7492-29-7
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C18-H17-Cl-N2-O
- MOLECULAR WEIGHT :
- 312.82
- WISWESSER LINE NOTATION :
- T C6 B676 KN MVN&TT&J N1 RG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1730 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,163,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 465 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,163,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1160 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,163,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 233 mg/kg
- TOXIC EFFECTS :
- Behavioral - anticonvulsant
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
20037) V.6- 1963- Volume(issue)/page/year: 11,777,1968
