N-(2-乙酰氨基苯乙基)-1-羟基-2-萘酰胺

  • 基本信息
  • 物化性质
  • 安全信息
  • 毒理性
  • MSDS
  • 海关数据
  • 结构与计算化学

N-(2-乙酰氨基苯乙基)-1-羟基-2-萘酰胺 基本信息

中文名称:
N-(2-乙酰氨基苯乙基)-1-羟基-2-萘酰胺 
中文别名:
N-(2-乙酰氨基苯乙基)-1-羟基-2-萘酰胺;
Color coupling agent, c-16 Labotest-bb lt00441227 N-(2-Acetamidophenethyl)-1-hydroxy-2-naphthamide 1-Hydroxy-2-(beta-(2’-acetamidophenyl)-ethyl)-naphthamide N-(2-(2-(Acetylamino)phenyl)ethyl)-1-hydroxy-2-naphthalenecarboxamid N-(O-(acetylamino)phenethyl)- 
英文名称:
N-(2-Acetamidophenethyl)-1-hydroxy-2-naphthamide
英文别名:
N-[2-(2-acetamidophenyl)ethyl]-1-hydroxynaphthalene-2-carboxamide;
EINECS 226-055-2 
CAS No.:
5254-41-1
分 子 式:
C21H20N2O3
分 子 量:
348.39
精确分子量:
348.14700
PSA:
78.43000
EINECS:
226-055-2
InChI:
The Key: HNLJTZUJURZMTN-UHFFFAOYSA-N
安全术语:
S24/25
分子结构式:
SDS:
查看

N-(2-乙酰氨基苯乙基)-1-羟基-2-萘酰胺 物化性质

密度:
1.277g/cm3
熔点:
225-227ºC
沸点:
676.3ºC at 760mmHg
闪点:
362.8ºC
折射率:
1.679
存储条件/存储方法:

密封储存,储存于阴凉、干燥的库房。

稳定性相关:

常温常压下稳定,避免与不相容材料,强氧化剂接触。

N-(2-乙酰氨基苯乙基)-1-羟基-2-萘酰胺 安全信息

海关代码:
2924299090
安全标志:
S24/25:防止皮肤和眼睛接触。

N-(2-乙酰氨基苯乙基)-1-羟基-2-萘酰胺 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QJ1885000
CHEMICAL NAME :
2-Naphthalenecarboxamide, N-(o-(acetylamino)phenethyl)-1-hydroxy-
CAS REGISTRY NUMBER :
5254-41-1
LAST UPDATED :
199710
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C21-H20-N2-O3
MOLECULAR WEIGHT :
348.43
WISWESSER LINE NOTATION :
L66J BQ CMV2R BMV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>3200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971
毒理学数据:

1、急性毒性:大鼠经口LD50>3200mg/kg;大鼠经腹腔LD50800mg/kg;豚鼠经皮肤接触LD50>1mg/kg

N-(2-乙酰氨基苯乙基)-1-羟基-2-萘酰胺 MSDS

Name: N-(2-acetamidophenethyl)-1-hydroxy-2-naphthamide Material Safety Data Sheet
Synonym: Color coupling agent; C-1
CAS: 5254-41-1
Section 1 - Chemical Product   MSDS Name:N-(2-acetamidophenethyl)-1-hydroxy-2-naphthamide Material Safety Data Sheet
Synonym:Color coupling agent; C-1

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
5254-41-1 N-(2-Acetamidophenethyl)-1-hydroxy-2-n >98 % 226-055-2
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
The toxicological properties of this substance have not been fully investigated.
Inhalation:
The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
  Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal.

Section 7 - HANDLING and STORAGE
  Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Storage:
Store in a cool, dry place. Keep container closed when not in use.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 5254-41-1: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves and clothing to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Solid
Color: white
Odor: none reported
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 225.00 - 227.00
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: Moderately soluble in water.
Specific Gravity/Density: Not available.
Molecular Formula: C21 H20 N2 O3
Molecular Weight: 348.40

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Irritating and toxic fumes and gases.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 5254-41-1: QJ1885000 LD50/LC50:
CAS# 5254-41-1: Dermal, guinea pig: LD50 = >1 gm/kg; Oral, rat: LD50 = >3200 mg/kg.
Carcinogenicity:
N-(2-Acetamidophenethyl)-1-hydroxy-2-naphthamide - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
 

Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
 
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
WGK (Water Danger/Protection)
CAS# 5254-41-1: No information available.
Canada
CAS# 5254-41-1 is listed on Canada's DSL List.
CAS# 5254-41-1 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 5254-41-1 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A

N-(2-乙酰氨基苯乙基)-1-羟基-2-萘酰胺 海关数据

中国海关编码:2924299090

概述:
2924299090. 其他环酰胺(包括环氨基甲酸酯)(包括其衍生物以及他们的盐). 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素:
品名, 成分含量, 用途, 包装
摘要/Summary:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

N-(2-乙酰氨基苯乙基)-1-羟基-2-萘酰胺 分子结构与计算化学数据

计算化学数据

1.疏水参数计算参考值(XlogP):3.8

2.氢键供体数量:3

3.氢键受体数量:3

4.可旋转化学键数量:5

5.互变异构体数量:15

6.拓扑分子极性表面积78.4

7.重原子数量:26

8.表面电荷:0

9.复杂度:496

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

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