交联聚维酮

  • 基本信息
  • 制备方法及用途
  • 物化性质
  • 安全信息
  • 毒理性
  • MSDS
  • 结构与计算化学

交联聚维酮 基本信息

中文名称:
交联聚维酮 
中文别名:
交联聚乙烯基吡咯烷酮;
交联聚乙烯吡咯烷酮;
交联聚维酮;
聚乙烯聚吡咯烷酮交联(PVPP);
PVP-P(交联聚合物);
1-ethenylpyrrolidin-2-one 
英文名称:
Polyvinylpolypyrrolidone cross-linked
英文别名:
1-ethenylpyrrolidin-2-one;
88-12-0;
1-Vinyl-2-pyrrolidinone;
Vinylpyrrolidone;
polyvinylpolypyrrolidone;
Polyvinylpyrrolidone;
Polyvinylpyrrolidone (PVP-P);
Pvpp;
Povidone;
Polyvidone;
Poly(vinylpolypyrrolidone);
crospovidone;
N-Vinylpyrrolidone;
1-Vinyl-2-pyrrolidone;
2-Pyrrolidinone,1-ethenyl 
CAS No.:
25249-54-1
分 子 式:
(C6H9NO)n
分 子 量:
111.14200
精确分子量:
111.06800
PSA:
20.31000
MDL:
MFCD00149016
EINECS:
201-800-4
InChI:
InChI=1/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2
风险术语:
S24/25
安全术语:
S24/25;S22;
分子结构式:
SDS:
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交联聚维酮 制备方法及用途

制备方法

由于PVPP的高分子量和交联结构,不溶于水但遇水能迅速将水引入,促使其网络结构膨胀产生崩解作用,所以PVPP是医药上广泛应用的片剂崩解剂。又因为分子具有酰胺键及吸附多酚分子上的氢氧基从而形成氢键,可以吸附多酚,提高酒体的非生物稳定性。因此,可用作啤酒、果酒、饮料酒的稳定剂,延长其货架寿命达三百天,并改善其透明度、色泽和味道。另外被广泛用作悬浮稳定剂,药物成分络合剂,植物性药物中单宁及多酚物质的络合剂。该产品有一次性和再生性两种规格,一次性PVPP适合中小企业使用;再生性PVPP需购置专用过滤设备,但PVPP可回收利用,适合大型啤酒厂使用。

用途简介

用途

用于饮料、医药行业

交联聚维酮 物化性质

密度:
1.144g/cm3
熔点:
165 °C (dec.)(lit.)
沸点:
217.6°C at 760 mmHg
闪点:
93.9°C
存储条件/存储方法:

保持贮藏器密封

放入紧密的贮藏器内,储存在阴凉,干燥的地方

稳定性相关:

如果遵照规格使用和储存则不会分解

避免接触氧化物

其它信息:

1.      性状:白色或近白色,具有吸湿性易流动的粉末,无臭或微臭

2.      密度(g/mL,25/4℃):未确定

3.      相对蒸汽密度(g/mL,空气=1):未确定

4.      熔点(ºC):300

5.      沸点(ºC,常压):未确定

6.      沸点(ºC,5.2kPa):未确定

7.      折射率:未确定

8.      闪点(ºC):未确定

9.      比旋光度(º):未确定

10.   自燃点或引燃温度(ºC):未确定

11.   蒸气压(kpa,20ºC):未确定

12.   饱和蒸气压(kPa,60ºC):未确定

13.   燃烧热(KJ/mol):未确定

14.   临界温度(ºC):未确定

15.   临界压力(KPa):未确定

16.   油水(辛醇/水)分配系数的对数值:未确定

17.   爆炸上限(%,V/V):未确定

18.   爆炸下限(%,V/V):未确定

19.   溶解性:不溶于水、碱、酸及常用有机溶剂

交联聚维酮 安全信息

安全说明:
22-24/25

交联聚维酮 毒理性

生态数据:

对水是稍微危害的,若无政府许可,勿将材料排入周围环境。

交联聚维酮 MSDS

Name: Polyvinylpyrrolidone cross-linked Material Safety Data Sheet
Synonym: Polyvinylpolypyrrolidone; PV
CAS: 25249-54-1
Section 1 - Chemical Product   MSDS Name:Polyvinylpyrrolidone cross-linked Material Safety Data Sheet
Synonym:Polyvinylpolypyrrolidone; PV

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
25249-54-1 Polyvinylpyrrolidone, cross-linked 100 unlisted
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
  Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation. Cover with dry earth, dry sand, or other non-combustible material followed with plastic sheet to minimize spreading and contact with water.

Section 7 - HANDLING and STORAGE
  Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 25249-54-1: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Crystalline powder
Color: Off-White Micro-Crystalline Powder
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: > 300 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula:
Molecular Weight:

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, strong oxidants.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 25249-54-1 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Polyvinylpyrrolidone, cross-linked - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION
 

Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
 
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
S 28A After contact with skin, wash immediately with
plenty of water.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 25249-54-1: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 25249-54-1 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 25249-54-1 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

交联聚维酮 分子结构与计算化学数据

计算化学数据

1、  疏水参数计算参考值(XlogP):0.4

2、  氢键供体数量:0

3、  氢键受体数量:1

4、  可旋转化学键数量:1

5、  互变异构体数量:2

6、  拓扑分子极性表面积(TPSA):20.3

7、  重原子数:8

8、  表面电荷:0

9、  复杂度:120

10、          同位素原子数量:0

11、          确定原子立构中心数量:0

12、          不确定原子立构中心数量:0

13、          确定化学键立构中心数量:0

14、          不确定化学键立构中心数量:0

15、          共价键单元数量:1

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