亮磺胺五羟黄酮

  • 基本信息
  • 物化性质
  • 安全信息
  • 毒理性
  • MSDS
  • 结构与计算化学
  • 下游产品

亮磺胺五羟黄酮 基本信息

中文名称:
亮磺胺五羟黄酮 
中文别名:
亮磺胺五羟黄酮;
C.I.酸性黄3;
酸性黄7 
英文名称:
1H-Benz[de]isoquinoline-5-sulfonicacid, 6-amino-2,3-dihydro-2-(4-methylphenyl)-1,3-dioxo-, sodium salt (1:1)
英文别名:
1H-Benz[de]isoquinoline-5-sulfonic acid, 6-amino-2,3-dihydro-2-(4-methylphenyl)-1,3-dioxo-, sodium salt (1:1);
1H-Benz[de]isoquinoline-5-sulfonic acid, 6-amino-2,3-dihydro-1,3-dioxo-2-p-tolyl-, monosodium salt (8CI);
1H-Benz[de]isoquinoline-5-sulfonic acid, 6-amino-2,3-dihydro-1,3-dioxo-2-p-tolyl-, sodium salt (7CI);
1H-Benz[de]isoquinoline-5-sulfonic acid, 6-amino-2,3-dihydro-2-(4-methylphenyl)-1,3-dioxo-, monosodium salt (9CI);
Lissamine Flavine FFS (6CI);
Acid New Yellow GMF;
Acid Yellow 7;
Brilliant Acid Flavine 10J;
Brilliant Acid Yellow 8G;
Brilliant Sulfo Flavin FFA;
Brilliant Sulfo Flavine;
Brilliant Sulfo Flavine FF;
Brilliant Sulfo Flavine FFA;
Brilliant Sulfoflavin;
Brilliant Sulfoflavin FF;
Brilliant Sulphaflavine;
Brilliant Sulpho Flavine FF;
Brilliant Sulpho Flavine FFA;
Brilliant sulfaflavine;
C.I. 56205;
C.I. Acid Yellow 7;
Dyacid Yellow FF;
Fenazo Yellow XX;
Kayaku Acid Brilliant Flavine FF;
Lissamine Flavine;
Lissamine Flavine FF;
Lissamine Yellow FF;
Naphthazine Flavine FF;
Sulfacid Brilliant Yellow 10J;
Sulfaflavine;
Triacid Flavine FF 
CAS No.:
2391-30-2
分 子 式:
C19H14N2O5S.Na
分 子 量:
418.4
精确分子量:
405.05212
PSA:
130.67000
EINECS:
219-238-3
InChI:
The Key: HYLDLLCHFLSKAG-UHFFFAOYSA-M
分子结构式:
SDS:
查看

亮磺胺五羟黄酮 物化性质

其它信息:

1.      性状:未确定

2.      密度(g/L,25ºC):未确定

3.      相对蒸汽密度(g/mL,空气=1):未确定

4.      熔点(ºC):未确定

5.      沸点(ºC,常压):未确定

6.      沸点(ºC 18mmHg):未确定

7.      折射率nD20):未确定

8.      闪点(ºF未确定

9.      比旋光度(,):未确定

10.   自燃点或引燃温度(ºC):未确定

11.   蒸气压(Pa,20ºC):未确定

12.   饱和蒸气压(kPa,20ºC):未确定

13.   燃烧热(KJ/mol):未确定

14.   临界温度(ºC):未确定

15.   临界压力(KPa):未确定

16.   油水(辛醇/水)分配系数的对数值:未确定

17.   爆炸上限(%,V/V):未确定

18.   爆炸下限(%,V/V):未确定

19.   溶解性:未确定

亮磺胺五羟黄酮 安全信息

安全说明:
S24/25

亮磺胺五羟黄酮 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DE4098000
CHEMICAL NAME :
1H-Benz(de)isoquinoline-5-sulfonic acid, 2,3-dihydro-6-amino-1,3-dioxo-2-(p-tolyl)-, monosodium salt
CAS REGISTRY NUMBER :
2391-30-2
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C19-H13-N2-O5-S.Na
MOLECULAR WEIGHT :
404.39
WISWESSER LINE NOTATION :
T666 1A M CVNVJ DR D1& HSWO IZ &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
110 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 44,225,1978
毒理学数据:

1、急性毒性:小鼠静脉LD50110mg/kg

亮磺胺五羟黄酮 MSDS

Name: Brilliant Sulphaflavine Material Safety Data Sheet
Synonym: 1H-Benz(de)Isoquinoline-5-Sulfonic Acid; 2,3-Dihydro-6-Amino-1,3- Dioxo-2-(P-Tolyl)-; Monosodium Salt
CAS: 2391-30-2
Section 1 - Chemical Product   MSDS Name:Brilliant Sulphaflavine Material Safety Data Sheet
Synonym:1H-Benz(de)Isoquinoline-5-Sulfonic Acid; 2,3-Dihydro-6-Amino-1,3- Dioxo-2-(P-Tolyl)-; Monosodium Salt

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
2391-30-2 Brilliant Sulphaflavine 100% 219-238-3
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
  Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

Section 7 - HANDLING and STORAGE
  Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 2391-30-2: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Powder
Color: yellow to orange
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: soluble
Specific Gravity/Density:
Molecular Formula: C20H15NaN2O5S
Molecular Weight: 404.36

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide, nitrogen.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 2391-30-2: DE4098000 LD50/LC50:
Not available.
Carcinogenicity:
Brilliant Sulphaflavine - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
 

Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
 
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
S 28A After contact with skin, wash immediately with
plenty of water.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 2391-30-2: No information available.
Canada
CAS# 2391-30-2 is listed on Canada's DSL List.
CAS# 2391-30-2 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 2391-30-2 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A

亮磺胺五羟黄酮 分子结构与计算化学数据

计算化学数据

1、   疏水参数计算参考值(XlogP):

2、   氢键供体数量:2

3、   氢键受体数量:6

4、   可旋转化学键数量:2

5、   互变异构体数量:3

6、   拓扑分子极性表面积(TPSA):118

7、   重原子数量:28

8、   表面电荷:0

9、   复杂度:725

10、同位素原子数量:0

11、确定原子立构中心数量:0

12、不确定原子立构中心数量:0

13、确定化学键立构中心数量:0

14、不确定化学键立构中心数量:0

15、共价键单元数量:2

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