产品供求
基本信息
- 中文名称：
-
- 中文别名：
-
- 英文名称：
- (E)-3-[(6R,6aS)-4-hydroxy-6-methoxy-3-methyl-11-oxo-5,6,6a,7-tetrahydropyrrolo[2,1-c][1,4]benzodiazepin-8-yl]prop-2-enamide
- 英文别名：
- (E)-3-[(6R,6aS)-4-hydroxy-6-methoxy-3-methyl-11-oxo-5,6,6a,7-tetrahydropyrrolo[2,1-c][1,4]benzodiazepin-8-yl]prop-2-enamide;
Roche 5-9000;
Anthramycin-methylether;
Antibiotic A;
Anthramycin 11-methyl ether;
11-O-Methyl-anthramycin
- CAS No.：
- 5544-25-2
- 分 子 式：
- C17H19N3O4
- 分 子 量：
- 329.35000
- 精确分子量：
- 329.13800
- PSA：
- 104.89000
- InChI：
- The Key: YRMCBQLZVBXOSJ-PCFSSPOYSA-N
- 分子结构式：
-
- SDS：
- 查看
物化性质
- 密度：
- 1.4g/cm3
- 沸点：
- 631.8ºC at 760 mmHg
- 闪点：
- 335.9ºC
- 折射率：
- 1.672
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UY8429500
- CHEMICAL NAME :
- 1H-Pyrrolo(2,1-c)(1,4)benzodiazepine-2-acrylamide,
5,10,11,11a-tetrahydro-9-hydroxy-
11-methoxy-8-methyl-5-oxo-, (E)-, monohydrate
- CAS REGISTRY NUMBER :
- 5544-25-2
- LAST UPDATED :
- 199306
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C17-H19-N3-O4.H2-O
- MOLECULAR WEIGHT :
- 347.41
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3400 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 730 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2900 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TYPE OF TEST :
- DNA inhibition
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - mouse Ascites tumor
- DOSE/DURATION :
- 5 umol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
29,2195,1969
