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基本信息
- 中文名称：
-
- 中文别名：
-
- 英文名称：
- ethyl 4-carbamimidoylbenzoate,hydrochloride
- 英文别名：
- ethyl 4-carbamimidoylbenzoate,hydrochloride;
4-allyloxyacetoacetate;
ethyl 4-allyloxy-3-oxobutanoate;
4-amidino-benzoic acid ethyl ester hydrochloride;
ethyl 4-amidinobenzoate.HCl;
ethyl 4-allyloxy-6,8-dimethoxynaphthalene-2-carboxylate;
Ethyl 4-allyloxyacetoacetate;
4-carbamimidoyl-benzoic acid ethyl ester,hydrochloride;
4-allyloxy-6,8-dimethoxynaphthalene-2-carboxylic acid ethyl ester;
4-Carbamimidoyl-benzoesaeure-aethylester,Hydrochlorid;
Butanoic acid,3-oxo-4-(2-propenyloxy)-,ethyl ester;
ethyl 4-amidinobenzoate hydrochloride;
4-carbethoxy-benzamidin-hydrochlorid;
ethyl 4-allyloxy-3-oxobutyrate;
ethyl 4-[amino(imino)methyl]benzoate hydrochloride
- CAS No.：
- 5418-97-3
- 分 子 式：
- C10H13ClN2O2
- 分 子 量：
- 228.67500
- 精确分子量：
- 228.06700
- PSA：
- 76.17000
- InChI：
- The Key: YQLMHXJICJZZFV-UHFFFAOYSA-N
- 分子结构式：
-
- SDS：
- 查看
物化性质
- 沸点：
- 310.8ºC at 760 mmHg
- 闪点：
- 141.7ºC
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DG1120000
- CHEMICAL NAME :
- Benzoic acid, p-amidino-, ethyl ester,
monohydrochloride
- CAS REGISTRY NUMBER :
- 5418-97-3
- LAST UPDATED :
- 199606
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C10-H12-N2-O2.Cl-H
- MOLECULAR WEIGHT :
- 228.70
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 280 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- 85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2
vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year:
1,243,1946
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 297 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 57,81,1936
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- >65 mg/kg
- TOXIC EFFECTS :
- Behavioral - ataxia
Gastrointestinal - nausea or vomiting
- REFERENCE :
- 85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2
vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year:
1,243,1946
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 238 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 57,81,1936
** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 1360 mg/kg/8D-I
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - food intake (animal)
Gastrointestinal - nausea or vomiting
- REFERENCE :
- 85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2
vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year:
1,243,1946
