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氯地孕酮 基本信息
- 中文名称：
- 氯地孕酮
- 中文别名：
- 氯地孕酮;
2-cyano-N-(2,4-difluorophenyl)-Acetamide;
2-CYANO-N-[3-(TRIFLUOROMETHYL)PHENYL]ACETAMIDE;
3',5'-Di-O-Acetyl-5-Iodo-2'-Deoxyuridine;
3',5'-Diacetyl-5-Iodo-2'-Deoxyuridine;
3-(methoxycarbonyl)-5-nitrobenzoate;
methyl 5-nitroisophthalate;
monomethyl 5-nitroisophthalate;
5-Hydroxy-indole;
5-Hydroxyindole;
Methylthymol blue tetrasodium salt;
Methyl thymol blue;
Methylthymol Blue, tetrasodium salt;
Pyrazole-3-carboxylic acid, 4,5-dihydro-5-oxo-1-(4-sulfoph
- 英文名称：
- Pregna-4,6-diene-3,20-dione,6-chloro-17-hydroxy-
- 英文别名：
- Chlormadinone;
(8R,9S,10R,13S,14S,17R)-17-acetyl-6-chloro-17-hydroxy-10,13-dimethyl-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one
- CAS No.：
- 1961-77-9
- 分 子 式：
- C21H27ClO3
- 分 子 量：
- 362.89
- 精确分子量：
- 362.16500
- PSA：
- 54.37000
- EINECS：
- 217-802-3
- InChI：
- InChI=1/C21H27ClO3/c1-12(23)21(25)9-6-16-14-11-18(22)17-10-13(24)4-7-19(17,2)15(14)5-8-20(16,21)3/h10-11,14-16,25H,4-9H2,1-3H3/t14-,15+,16+,19-,20+,21+/m1/s1
- 分子结构式：
-
- SDS：
- 查看
氯地孕酮 物化性质
- 密度：
- 1.24 g/cm3
- 沸点：
- 506.7ºC at 760 mmHg
- 闪点：
- 260.2ºC
- 折射率：
- 1.582
- 蒸汽压：
- 2.18E-12mmHg at 25°C
- 存储条件/存储方法：
- 库房低温通风干燥
氯地孕酮 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TU3730000
- CHEMICAL NAME :
- Pregna-4,6-diene-3,20-dione, 6-chloro-17-hydroxy-
- CAS REGISTRY NUMBER :
- 1961-77-9
- LAST UPDATED :
- 199109
- DATA ITEMS CITED :
- 13
- MOLECULAR FORMULA :
- C21-H27-Cl-O3
- MOLECULAR WEIGHT :
- 362.93
- WISWESSER LINE NOTATION :
- L E5 B666 OV KU MUTJ A1 E1 FV1 FQ LG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: -,378,1990
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: -,378,1990
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: -,378,1990
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: -,378,1990
** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 200 ug/kg
- SEX/DURATION :
- female 20 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - uterus, cervix, vagina
Reproductive - Fertility - female fertility index (e.g. # females pregnant
per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- FESTAS Fertility and Sterility. (American Fertility Soc., 608 13th Ave. S,
Birmingham, AL 35282) V.1- 1950- Volume(issue)/page/year: 16,158,1965
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 3650 ug/kg
- SEX/DURATION :
- female 52 week(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant
per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- BMJOAE British Medical Journal. (British Medical Assoc., BMA House,
Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year:
2,730,1969
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 16800 ug/kg
- SEX/DURATION :
- male 21 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland,
accessory glands
- REFERENCE :
- ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E,
DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 49,145,1965
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 50400 ug/kg
- SEX/DURATION :
- male 21 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - testes, epididymis, sperm duct
- REFERENCE :
- ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E,
DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 49,145,1965
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 150 ug/kg
- SEX/DURATION :
- female 3 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - other measures of fertility
- REFERENCE :
- ENDOAO Endocrinology (Baltimore). (Williams & Wilkins Co., 428 E. Preston
St., Baltimore, MD 21203) V.1- 1917- Volume(issue)/page/year:
81,1251,1967
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- DOSE :
- 50 ug/kg
- SEX/DURATION :
- female 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - other measures of fertility
- REFERENCE :
- STEDAM Steroids. (Holden-Day Inc., 4432 Telegraph Ave., Oakland, CA 94609)
V.1- 1963- Volume(issue)/page/year: 7,341,1966
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- DOSE :
- 500 ug/kg
- SEX/DURATION :
- female 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
number of implants per female; total number of implants per corpora lutea)
- REFERENCE :
- STEDAM Steroids. (Holden-Day Inc., 4432 Telegraph Ave., Oakland, CA 94609)
V.1- 1963- Volume(issue)/page/year: 5,699,1965
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 300 mg/kg
- SEX/DURATION :
- female 1-3 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
- REFERENCE :
- FESTAS Fertility and Sterility. (American Fertility Soc., 608 13th Ave. S,
Birmingham, AL 35282) V.1- 1950- Volume(issue)/page/year: 20,211,1969
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 300 ug/kg
- SEX/DURATION :
- female 2 day(s) pre-mating
female 1 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
number of implants per female; total number of implants per corpora lutea)
- REFERENCE :
- AJOGAH American Journal of Obstetrics and Gynecology. (C.V. Mosby Co.,
11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1920-
Volume(issue)/page/year: 117,167,1973
郑州力本生物技术有限公司
- 产品介绍：
-
产品名称：氯地孕酮
Cas号：1961-77-9
纯度：99
包装信息：25/桶kg,1/袋kg
价格：5,500.0元 - 6,000.0元
- 联系方式：
-
联系人：刘林
电话：0371-86536307
手机：13949119001
湖北佩孜医药科技有限公司
- 产品介绍：
-
产品名称：氯地孕酮
Cas号：1961-77-9
纯度：98%
包装信息：1000kg,100kg,25kg,1kg
价格：洽谈
- 联系方式：
-
联系人：龚先生
电话：17720472265
手机：17720472265
湖北瑞诺医药科技有限公司
- 产品介绍：
-
产品名称：醋酸氯地孕酮杂质
Cas号：1961-77-9
纯度：99%
包装信息：10-25-50-100mg
价格：洽谈
- 联系方式：
-
联系人：汪经理
电话：0714-5316360
手机：13165688766
浙江省仙居县捷大医药化工有限公司
- 产品介绍：
-
产品名称：氯地孕酮
Cas号：1961-77-9
纯度：
包装信息：洽谈
价格：洽谈
- 联系方式：
-
联系人：朱先生
电话：0576-87750900
手机：
浙江仙居捷大医药化工有限公司
- 产品介绍：
-
产品名称：氯地孕酮
Cas号：1961-77-9
纯度：
包装信息：洽谈
价格：洽谈
- 联系方式：
-
联系人：朱少敏
电话：+86-576-87750871 87750872
手机：13905865272
