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阿普比妥 基本信息
- 中文名称：
- 阿普比妥
- 中文别名：
- 阿普比妥;
烯丙异丙巴比妥
- 英文名称：
- 2,4,6(1H,3H,5H)-Pyrimidinetrione,5-(1-methylethyl)-5-(2-propen-1-yl)-
- 英文别名：
- aprobarbital;
Numal;
Aprozal;
Aprobarbitone;
Allonal;
Aprobarbital;
Allypropymal;
Allylpropymal;
Aprobarbita;
Alurate;
5-propan-2-yl-5-prop-2-enyl-1,3-diazinane-2,4,6-trione;
Allional;
5-allyl-5-isopropylbarbituric acid
- CAS No.：
- 77-02-1
- 分 子 式：
-
C10H14N2O3
- 分 子 量：
- 210.23
- 精确分子量：
- 210.10000
- PSA：
- 75.27000
- InChI：
- The Key: UORJNBVJVRLXMQ-UHFFFAOYSA-N
- 危险品标志：
-
- 风险术语：
-
- 安全术语：
- 分子结构式：
-
- SDS：
- 查看
阿普比妥 物化性质
- 密度：
- 1.086 g/cm3
- 折射率：
- 1.476
- 存储条件/存储方法：
- 库房通风低温干燥,与食品原料分开存放
阿普比妥 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CP8925000
- CHEMICAL NAME :
- Barbituric acid, 5-allyl-5-isopropyl-
- CAS REGISTRY NUMBER :
- 77-02-1
- BEILSTEIN REFERENCE NO. :
- 0180858
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C10-H14-N2-O3
- MOLECULAR WEIGHT :
- 210.26
- WISWESSER LINE NOTATION :
- T6VMVMV FHJ FY1&1 F2U1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 44,325,1932
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 12,389,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 350 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 8,25,1958
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 160 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 44,325,1932
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 90 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 44,325,1932
*** REVIEWS ***
TOXICOLOGY REVIEW
FNSCA6 Forensic Science. (Lausanne, Switzerland) V.1-11, 1972-78. For pub
lisher information, see FSINDR. Volume(issue)/page/year: 2,67,1973
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 84585
No. of Facilities: 805 (estimated)
No. of Industries: 1
No. of Occupations: 1
No. of Employees: 805 (estimated)
