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双甲乙炔睾酮 基本信息
- 中文名称：
- 双甲乙炔睾酮
- 中文别名：
- 双甲乙炔睾酮;
地美炔酮
- 英文名称：
- Androst-4-en-3-one,17-hydroxy-6-methyl-17-(1-propynyl)-, (6a,17b)-
- 英文别名：
- (6S,8R,9S,10R,13S,14S,17S)-17-hydroxy-6,10,13-trimethyl-17-prop-1-ynyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one;
Secrosteron;
Dimethisterone;
Dimethisteron;
Dimethisterone anhydrous;
6a,21-dimethylethisterone;
Lutogan
- CAS No.：
- 79-64-1
- 分 子 式：
-
C23H32O2
- 分 子 量：
- 340.5
- 精确分子量：
- 340.24000
- PSA：
- 37.30000
- InChI：
- The Key: LVHOURKCKUYIGK-RGUJTQARSA-N
- 危险品标志：
-
- 风险术语：
-
- 安全术语：
-
- 分子结构式：
-
- SDS：
- 查看
双甲乙炔睾酮 物化性质
- 密度：
- 1.11g/cm3
- 沸点：
- 479ºC at 760 mmHg
- 闪点：
- 203.5ºC
- 折射率：
- 1.566
双甲乙炔睾酮 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BV8510000
- CHEMICAL NAME :
- Androst-4-en-3-one,
17-beta-hydroxy-6-alpha-methyl-17-(1-propynyl)-
- CAS REGISTRY NUMBER :
- 79-64-1
- LAST UPDATED :
- 199510
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C23-H32-O2
- MOLECULAR WEIGHT :
- 340.55
- WISWESSER LINE NOTATION :
- L E5 B666 OV MUTJ A1 E1 FQ F1UU2 L1 -A&L -B&AEF
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 100 mg/kg
- SEX/DURATION :
- female 17-20 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - urogenital system
- REFERENCE :
- ECJPAE Endocrinologia Japonica. (Japan Pub. Trading Co., Ltd., POB 5030,
Tokyo International, Tokyo, Japan) V.1- 1954- Volume(issue)/page/year:
24,77,1977
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 175 mg/kg
- SEX/DURATION :
- female 15-21 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - urogenital system
- REFERENCE :
- ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E,
DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 38,128,1961
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 70 mg/kg
- SEX/DURATION :
- female 14 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - ovaries, fallopian tubes
Reproductive - Fertility - other measures of fertility
- REFERENCE :
- CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1-
1970- Volume(issue)/page/year: 5,57,1972
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 28 mg/kg
- SEX/DURATION :
- female 14 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - uterus, cervix, vagina
- REFERENCE :
- CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1-
1970- Volume(issue)/page/year: 5,57,1972
*** REVIEWS ***
IARC Cancer Review:Animal Inadequate Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 21,377,1979
