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亮氨卡因 基本信息
- 中文名称：
- 亮氨卡因
- 中文别名：
- 亮氨卡因;
2-(二乙氨基)-4-甲基戊基-4-氨基苯甲酸 2-(diethylamino)-4-methylpentyl 4-aminobenzoate, monomethanesulphonate
- 英文名称：
- 2-(diethylamino)-4-methylpentyl4-aminobenzoate,monomethanesulphonate
- 英文别名：
- 2-(diethylamino)-4-methylpentyl 4-aminobenzoate, monomethanesulphonate;
Panthesine;
Leucinocaine mesylate;
4-Amino-benzoesaeure-(2-diaethylamino-4-methyl-pentylester),Methansulfonat;
Panthesin;
Leucinocaine;
2-(diethylamino)-4-methyl-1-pentanol;
2-Diethylamino-4-methyl-1-pentanol 4-aminobenoate monomethanesulfonate;
4-amino-benzoic acid-(2-diethylamino-4-methyl-pentylester),methanesulfonate;
monomethanesulfonate (salt);
Leucinocaine methanesulfonate;
4-aminobenzoate (ester);
monomethanesulfonate;
Leucinocainmesilat
- CAS No.：
- 135-44-4
- 分 子 式：
-
C18H32N2O5S
- 分 子 量：
- 388.52
- 精确分子量：
- 388.20300
- PSA：
- 118.31000
- EINECS：
- 205-191-6
- InChI：
- The Key: RFPVXZWXDPIKSD-UHFFFAOYSA-N
- 危险品标志：
-
- 风险术语：
-
- 安全术语：
- 分子结构式：
-
- SDS：
- 查看
亮氨卡因 物化性质
- 沸点：
- 417.1ºC at 760mmHg
- 闪点：
- 206ºC
- 蒸汽压：
- 3.65E-07mmHg at 25°C
亮氨卡因 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SA6475000
- CHEMICAL NAME :
- 1-Pentanol, 2-(diethylamino)-4-methyl-,
p-aminobenzoate (ester), monomethanesulfonate
- CAS REGISTRY NUMBER :
- 135-44-4
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C17-H28-N2-O2.C-H4-O3-S
- MOLECULAR WEIGHT :
- 388.58
- WISWESSER LINE NOTATION :
- ZR DVO1YN2&2&1Y1&1 &OSW1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville
Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year:
12,190,1932
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 49 mg/kg
- TOXIC EFFECTS :
- Behavioral - general anesthetic
- REFERENCE :
- WDMU** "Vergleichend-pharmakologische Untersuchungen ueber die haemolytische
Wirkung und die Toxizitat der Lokalanaesthetika, Dissertation," Walther, M.,
Pharmakologischen Instit Martin Luther-Universitat Halle-Wittenburg, Ger.
Dem. Rep., 1936 Volume(issue)/page/year: -,-,1936
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 240 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville
Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year:
12,190,1932
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 57,221,1936
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraspinal
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 10200 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 54,137,1935
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 112 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville
Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year:
12,190,1932
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville
Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year:
12,190,1932
亮氨卡因 海关数据
中国海关编码：2922499990
- 概述：
- 2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%
- 申报要素：
- 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
- 监管条件：
- A.入境货物通关单B.出境货物通关单
- 检验检疫：
- P.进境动植物、动植物产品检疫Q.出境动植物、动植物产品检疫R.进口食品卫生监督检验S.出口食品卫生监督检验M.进口商品检验N.出口商品检验
- 摘要/Summary：
- HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%
