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美西麦角 基本信息
- 中文名称：
- 美西麦角
- 中文别名：
- 美西麦角
- 英文名称：
- Ergoline-8-carboxamide,9,10-didehydro-N-[(1S)-1-(hydroxymethyl)propyl]-1,6-dimethyl-, (8b)-
- 英文别名：
- methysergide;
Metisergide;
Desernil;
Deseril;
Methysergid;
Sansert;
Metisergide [DCIT];
Desernyl;
Deseryl;
methsergide;
Methysergidum;
(6aR,9R)-N-[(2S)-1-hydroxybutan-2-yl]-4,7-dimethyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-9-carboxamide
- CAS No.：
- 361-37-5
- 分 子 式：
-
C21H27N3O2
- 分 子 量：
- 353.463
- 精确分子量：
- 353.21000
- PSA：
- 57.50000
- InChI：
- The Key: KPJZHOPZRAFDTN-ZRGWGRIASA-N
- 危险品标志：
-
- 风险术语：
-
- 安全术语：
- 分子结构式：
-
- SDS：
- 查看
美西麦角 物化性质
- 密度：
- 1.28g/cm3
- 沸点：
- 634.4ºC at 760mmHg
- 闪点：
- 337.5ºC
- 折射率：
- 1.658
美西麦角 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KE5300000
- CHEMICAL NAME :
- Ergoline-8-beta-carboxamide,
9,10-didehydro-N-(1-(hydroxymethyl)propyl)-1,6-dimeth
yl-
- CAS REGISTRY NUMBER :
- 361-37-5
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C21-H27-N3-O2
- MOLECULAR WEIGHT :
- 353.51
- WISWESSER LINE NOTATION :
- T C6656 1A P GN LN CUTT&&J EVMY2&1Q G1 L1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 28 ug/kg
- TOXIC EFFECTS :
- Behavioral - anorexia (human)
Behavioral - headache
Gastrointestinal - nausea or vomiting
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 16,220,1966
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 440 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3,
1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year:
2,17,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 185 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3,
1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year:
2,17,1963
