4-氨基-1,3,5-三甲基吡唑

  • 基本信息
  • 物化性质
  • 安全信息
  • 毒理性
  • MSDS
  • 海关数据
  • 结构与计算化学
  • 上游产品
  • 下游产品

4-氨基-1,3,5-三甲基吡唑 基本信息

中文名称:
4-氨基-1,3,5-三甲基吡唑 
中文别名:
1,3,5-三甲基-吡唑-4-胺;
4-氨基-1,3,5-三甲基吡唑;
4-氨基-1,3,5-三甲基-1H-吡唑 
英文名称:
4-amino-1,3,5-trimethylpyrazole
英文别名:
4-AMINO-1,3,5-TRIMETHYLPYRAZOLE;
1,3,5-trimethyl-1H-4-aminopyrazole;
AKOS PAO-0230;
4-Amino-1,3,5-trimethyl-1H-pyrazole;
4-Amino-2,3,5-trimethyl-2H-pyrazole;
1,3,5-trimethyl-1H-pyrazol-4-ylamine;
1,3,5-trimethyl-4-aminopyrazole;
4-amino-1,3,5-trimethyl-1H-pyrazole;
4-amino-1,3,5-trimethyl-pyrazol;
1,3,5-Trimethyl-4-pyrazolamine;
1,3,5-TRIMETHYL-1H-PYRAZOL-4-AMINE 
CAS No.:
28466-21-9
分 子 式:

C6H11N3

分 子 量:
125.17
精确分子量:
125.09500
PSA:
43.84000
MDL:
MFCD00052883
EINECS:
000-000-0
BRN:
110739
InChI:
InChI=1/C6H11N3/c1-4-6(7)5(2)9(3)8-4/h7H2,1-3H3
危险品标志:

IrritantXi

风险术语:

 

安全术语:
S22;S24/25
分子结构式:
SDS:
查看

4-氨基-1,3,5-三甲基吡唑 物化性质

外观与性状:
棕色固体
密度:
1.13 g/cm3
熔点:
96 °C
沸点:
236.3ºC at 760 mmHg
闪点:
96.7ºC
折射率:
1.568
蒸汽压:
0.048mmHg at 25°C
稳定性相关:

如果遵照规格使用和储存则不会分解,未有已知危险反应

避免氧化物

其它信息:

1.         性状:白色或灰黄色的晶体状粉末

2.         密度(g/mL,25):未确定

3.         相对蒸汽密度(g/mL,空气=1):未确定

4.         熔点(ºC):99-105

5.         沸点(ºC,常压):未确定

6.         沸点(ºC, KPa):未确定

7.         折射率:未确定

8.         闪点(ºC):未确定

9.         比旋光度(º):未确定

10.      自燃点或引燃温度(ºC):未确定

11.      蒸气压(Pa,23ºC):未确定

12.      饱和蒸气压(KPa,20ºC):未确定

13.      燃烧热(KJ/mol):未确定

14.      临界温度(ºC):未确定

15.      临界压力(KPa):未确定

16.      油水(辛醇/水)分配系数的对数值:未确定

17.      爆炸上限(%,V/V):未确定

18.      爆炸下限(%,V/V):未确定

19.      溶解性:不溶于水

4-氨基-1,3,5-三甲基吡唑 安全信息

海关代码:
2933199090
安全说明:
S22-S24/25
RTECS号:
UQ6125100
危险标志:
Xi: Irritant;

4-氨基-1,3,5-三甲基吡唑 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ6125100
CHEMICAL NAME :
Pyrazole, 4-amino-1,3,5-trimethyl-
CAS REGISTRY NUMBER :
28466-21-9
BEILSTEIN REFERENCE NO. :
0110739
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C6-H11-N3
MOLECULAR WEIGHT :
125.20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 25,592,1970
毒理学数据:

1、   急性毒性:小鼠皮下LD50>500mg/kg

生态数据:

通常对水是不危害的,若无政府许可,勿将材料排入周围环境。

4-氨基-1,3,5-三甲基吡唑 MSDS

Name: 1 3 5-Trimethyl-1H-pyrazol-4-amine 97% Material Safety Data Sheet
Synonym:
CAS: 28466-21-9
Section 1 - Chemical Product   MSDS Name:1 3 5-Trimethyl-1H-pyrazol-4-amine 97% Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
28466-21-9 1,3,5-Trimethyl-1H-pyrazol-4-amine 97% unlisted
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
  Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
  Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 28466-21-9: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Solid
Color: beige
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 101 - 102 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C6H11N3
Molecular Weight: 125

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 28466-21-9: UQ6125100 LD50/LC50:
Not available.
Carcinogenicity:
1,3,5-Trimethyl-1H-pyrazol-4-amine - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
 

Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
 
IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 28466-21-9: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 28466-21-9 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 28466-21-9 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

4-氨基-1,3,5-三甲基吡唑 海关数据

中国海关编码:2933199090

概述:
2933199090. 其他结构上有非稠合吡唑环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素:
品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
摘要/Summary:
2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

4-氨基-1,3,5-三甲基吡唑 分子结构与计算化学数据

计算化学数据

1.疏水参数计算参考值(XlogP):0.4

2.氢键供体数量:1

3.氢键受体数量:2

4.可旋转化学键数量:0

5.互变异构体数量:无

6.拓扑分子极性表面积43.8

7.重原子数量:9

8.表面电荷:0

9.复杂度:105

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

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