盐酸二甲弗林

  • 基本信息
  • 物化性质
  • 安全信息
  • 毒理性

盐酸二甲弗林 基本信息

中文名称:
盐酸二甲弗林 
中文别名:
盐酸二甲弗林;
8-[(二甲氨基)甲基]-7-甲氧基-3-甲基-2-苯基-4-苯并呲喃酮盐酸盐 
英文名称:
8-[(dimethylamino)methyl]-7-methoxy-3-methyl-2-phenyl-4-benzopyrone hydrochloride
英文别名:
Dimefline Hydrochloride;
DIMEFLINE HYDROCHLORIDE 
CAS No.:
2740-04-7
分 子 式:

C20H22ClNO3

分 子 量:
359.84700
精确分子量:
359.12900
PSA:
42.68000
EINECS:
220-366-7
InChI:
InChI=1/C20H21NO3.ClH/c1-13-18(22)15-10-11-17(23-4)16(12-21(2)3)20(15)24-19(13)14-8-6-5-7-9-14;/h5-11H,12H2,1-4H3;1H
危险品标志:

 

风险术语:

 

安全术语:

 

分子结构式:
SDS:
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盐酸二甲弗林 物化性质

沸点:
465.3ºC at 760 mmHg
闪点:
235.2ºC
蒸汽压:
7.81E-09mmHg at 25°C

盐酸二甲弗林 安全信息

危险类别码:
20/21/22

盐酸二甲弗林 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LK8575000
CHEMICAL NAME :
Flavone, 8-((dimethylamino)methyl)-7-methoxy-3-methyl-, hydrochloride
CAS REGISTRY NUMBER :
2740-04-7
LAST UPDATED :
199009
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C20-H21-N-O3.Cl-H
MOLECULAR WEIGHT :
359.88
WISWESSER LINE NOTATION :
T66 BO EVJ CR& D1 IO1 J1N1&1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
14 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,345,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 24,1239,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
12 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 128,176,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 128,176,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 128,176,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1480 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 6,263,1964

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产品介绍:
产品名称:盐酸二甲弗林 Cas号:2740-04-7 纯度:99% 包装信息:25kg,200kg 价格:洽谈
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