(S,S,S)-2-氮杂双环[3,3,0]辛烷-3-羧酸苄酯盐酸盐

  • 基本信息
  • 制备方法及用途
  • 物化性质
  • 安全信息
  • 毒理性
  • 海关数据
  • 上游产品
  • 下游产品

(S,S,S)-2-氮杂双环[3,3,0]辛烷-3-羧酸苄酯盐酸盐 基本信息

中文名称:
(S,S,S)-2-氮杂双环[3,3,0]辛烷-3-羧酸苄酯盐酸盐 
中文别名:
(S,S,S)-2-氮杂双环[3,3,0]辛烷-3-羧酸苄酯盐酸盐;
Homatropine HCl;
8-methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(phenyl)acetate hydrochloride (1:1);
aluminum salt;
Aluminium tristearate;
aluminium (tri) stearate;
Aluminium stearate tech;
Aluminium stearate white powder;
aluminium octadecanoate;
octadecanoate, aluminum salt;
Aluminium stearate;
CCRIS 599;
HSDB 6002;
NCI-C02335;
RCRA waste number U222;
Toluene, 2-amino-, hydrochloride;
o-Aminotoluene hydrochlori 
英文名称:
8-Azabicyclo[3.2.1]octan-3-ol,8-methyl-, benzoate (ester), hydrochloride, (3-exo)- (9CI)
英文别名:
tropacocaine hydrochloride;
Benzoesaeure-tropan-3exo-ylester,Hydrochlorid;
endo-benzoic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester hydrochloride;
pseudotropine benzoate hydrochloride;
3exo-benzoyloxy-tropane,hydrochloride;
8-azabicyclo(3.2.1)octan-3-ol,8-methyl-,benzoate (ester),hydrochloride,ex benzoylpseudotropine hydrochloride;
Tropacaine hydrochloride;
Pseudotropin;
tropacocain hydrochloride;
3exo-Benzoyloxy-tropan,Hydrochlorid;
Tropacocaine (8-methyl-8-azabicyclo[3.2.1]oct-3-yl) benzoate 
CAS No.:
637-23-0
分 子 式:
C15H19NO2.ClH
分 子 量:
281.7815中文名称:(S,S,S)-2-氮杂双环[3,3,0]辛烷-3-羧酸苄酯盐酸盐
精确分子量:
281.11800
PSA:
29.54000
EINECS:
211-281-6
InChI:
InChI=1/C15H19NO2.ClH/c1-16-12-7-8-13(16)10-14(9-12)18-15(17)11-5-3-2-4-6-11;/h2-6,12-14H,7-10H2,1H3;1H
分子结构式:
SDS:
查看

(S,S,S)-2-氮杂双环[3,3,0]辛烷-3-羧酸苄酯盐酸盐 制备方法及用途

制备方法

用于合成雷米普利药物

用途简介

(S,S,S)-2-氮杂双环[3,3,0]辛烷-3-羧酸苄酯盐酸盐 物化性质

沸点:
339.9ºC at 760 mmHg
闪点:
122.3ºC

(S,S,S)-2-氮杂双环[3,3,0]辛烷-3-羧酸苄酯盐酸盐 安全信息

海关代码:
2933990090

(S,S,S)-2-氮杂双环[3,3,0]辛烷-3-羧酸苄酯盐酸盐 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YM4201000
CHEMICAL NAME :
1-alpha-H,5-alpha-H-Tropan-3-alpha-ol, benzoate (ester), hydrochloride
CAS REGISTRY NUMBER :
637-23-0
LAST UPDATED :
198910
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C15-H19-N-O2.Cl-H
MOLECULAR WEIGHT :
281.81

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
350 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 7,227,1934
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
465 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RCSADO Research Communications in Substances Abuse. (PJD Pub. Ltd., P.O.Box 966, Westbury, NY 11590) V.1- 1980- Volume(issue)/page/year: 5,279,1984
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
42 mg/kg
TOXIC EFFECTS :
Behavioral - general anesthetic
REFERENCE :
WDMU** "Vergleichend-pharmakologische Untersuchungen ueber die haemolytische Wirkung und die Toxizitat der Lokalanaesthetika, Dissertation," Walther, M., Pharmakologischen Instit Martin Luther-Universitat Halle-Wittenburg, Ger. Dem. Rep., 1936 Volume(issue)/page/year: -,-,1936 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
120 mg/kg
SEX/DURATION :
female 7 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - Central Nervous System
REFERENCE :
RCSADO Research Communications in Substances Abuse. (PJD Pub. Ltd., P.O.Box 966, Westbury, NY 11590) V.1- 1980- Volume(issue)/page/year: 5,279,1984

(S,S,S)-2-氮杂双环[3,3,0]辛烷-3-羧酸苄酯盐酸盐 海关数据

中国海关编码:2933990090

概述:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素:
品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
摘要/Summary:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

(S,S,S)-2-氮杂双环[3,3,0]辛烷-3-羧酸苄酯盐酸盐 上游产品

(S,S,S)-2-氮杂双环[3,3,0]辛烷-3-羧酸苄酯盐酸盐 下游产品

推荐供应商更多供应商>>

湖北江民泰华化工有限公司

产品介绍:
产品名称:(S,S,S)-2-氮杂双环[3,3,0]辛烷-3-羧酸苄酯盐酸盐 Cas号:637-23-0 纯度:99% 包装信息:200kg,25kg 价格:洽谈
联系方式:
联系人:张经理 电话:13396038321 手机:13396038321

浙江花蝶染料化工有限公司

产品介绍:
产品名称:(S,S,S)-2-氮杂双环[3,3,0]辛烷-3-羧酸苄酯盐酸盐 Cas号:637-23-0 纯度: 包装信息:洽谈 价格:洽谈
联系方式:
联系人:顾敏伟 电话:0576-88828079 手机:

天台昌明化学制品有限公司

产品介绍:
产品名称:(S,S,S)-2-氮杂双环[3,3,0]辛烷-3-羧酸苄酯盐酸盐 Cas号:637-23-0 纯度: 包装信息:洽谈 价格:洽谈
联系方式:
联系人: 电话:86-576-3661858 手机: