尼可待因

  • 基本信息
  • 安全信息
  • 毒理性

尼可待因 基本信息

中文名称:
尼可待因 
中文别名:
尼可待因 
英文名称:
nicocodine
英文别名:
[(4R,4aR,7S,7aR,12bS)-9-methoxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl] pyridine-3-carboxylate;
Nicocodeine;
EINECS 222-990-5;
O-nicotinoyl-codeine;
NICOCODINE;
Nicocodinum [INN-Latin];
Lyopect;
DEA No. 9309;
Nicocodina [INN-Spanish];
Codeine,nicotinate (ester);
Nicotinic acid,ester with codeine;
RC 146 
CAS No.:
3688-66-2
分 子 式:
C24H24N2O4
分 子 量:
404.464
精确分子量:
404.17400
PSA:
60.89000
EINECS:
222-990-5
InChI:
The Key: RYBGRHAWFUVMST-MJFIPZRTSA-N
分子结构式:
SDS:
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尼可待因 安全信息

海关代码:
2939190024

尼可待因 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QD1225000
CHEMICAL NAME :
Morphinan-6-alpha-ol, 7,8-didehydro-4,5-alpha-epoxy-3-methoxy-17-methyl-, nicotinate (ester)
CAS REGISTRY NUMBER :
3688-66-2
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C24-H24-N2-O4
MOLECULAR WEIGHT :
404.50
WISWESSER LINE NOTATION :
T B6566 B6/CO 4ABBC R BX HO PN GHT&&TTJ JO1 P1 FOV- CT6NJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
37 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 143,466,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
840 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 143,466,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
280 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 143,466,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
48 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 143,466,1963

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