脂肪醇醚硫酸钠

  • 基本信息
  • 制备方法及用途
  • 物化性质
  • 安全信息
  • 毒理性
  • MSDS
  • 结构与计算化学

脂肪醇醚硫酸钠 基本信息

中文名称:
脂肪醇醚硫酸钠 
中文别名:
脂肪醇醚硫酸钠;
十二烷基聚氧乙烯醚硫酸钠;
十二烷基聚氧乙醚硫酸钠;
月桂醇聚醚硫酸酯钠 
英文名称:
Poly(oxy-1,2-ethanediyl),a-sulfo-w-(dodecyloxy)-, sodium salt (1:1)
英文别名:
Sodium lauryl polyoxyethylene ether sulfate;
Sodium laureth sulfate;
TRIDECYLBENZENE SODIUM SULFONATE;
tridecylbenzenesulfonicacidsodiumsalt;
sodium tridecylbenzenesulphonate;
sodium C12-14 lauryl ether sulfate;
tridecyl-benzenesulfonicacisodiumsalt 
CAS No.:
9004-82-4
分 子 式:

(C2H4O)nC12H26O4S.Na

分 子 量:
332.43200
精确分子量:
332.16300
PSA:
84.04000
InChI:
InChI=1/C14H30O5S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-18-13-14-19-20(15,16)17;/h2-14H2,1H3,(H,15,16,17);/q;+1/p-1
危险品标志:

 

风险术语:

 

安全术语:

 

分子结构式:
SDS:
查看

脂肪醇醚硫酸钠 制备方法及用途

制备方法

本品制备中包括月桂醇与环氧乙烷的缩合,缩合产物硫酸化,中和,压滤除残渣,滤液蒸馏脱醇五个工艺步骤。将452 kg月桂醇(羟值275~320)投入反应釜中,再把5kg氢氧化钾投入配减槽中,配制成50%的水溶液后投入反应釜中。抽真空,控制真空度在13.3kPa,逐步升温至120℃左右进行脱水。脱水完成后利用氮气置换空气,驱尽空气后升温至140~150℃,开动搅拌,在3 kPa下通入324kg环氧乙烷。然后将釜温逐渐降至5℃左右。加入硫酸进行酸化反应,1h后用烧碱、酒精溶液进行中和。中和后压滤除去滤渣后,滤液脱醇得成品。

合成制备方法

本品制备中包括月桂醇与环氧乙烷的缩合,缩合产物硫酸化,中和,压滤除残渣,滤液蒸馏脱醇五个工艺步骤。将452 kg月桂醇(羟值275~320)投入反应釜中,再把5kg氢氧化钾投入配减槽中,配制成50%的水溶液后投入反应釜中。抽真空,控制真空度在13.3kPa,逐步升温至120℃左右进行脱水。脱水完成后利用氮气置换空气,驱尽空气后升温至140~150℃,开动搅拌,在3 kPa下通入324kg环氧乙烷。然后将釜温逐渐降至5℃左右。加入硫酸进行酸化反应,1h后用烧碱、酒精溶液进行中和。中和后压滤除去滤渣后,滤液脱醇得成品。

用途简介

广泛应用于香波、浴液、餐具洗涤剂、复合皂等洗涤化妆用品,用于纺织工业润湿剂、清洁剂等。

用途

本品在纺织工业中用作维纶油剂和其他合成纤维油剂的组分。亦可作液体合成洗涤剂的原料,具有扩散性好、洗涤作用强的优点。

用于液体洗涤、餐洗、洗发香波、浴用洗涤等日用化学行业中,也用于纺织、造纸、皮革、机械、石油开采等行业。

脂肪醇醚硫酸钠 物化性质

外观与性状:
固体
稳定性相关:

有优良的洗涤俢。易产生大量泡沫。对合成纤维有抗静电、平滑柔软作用。属阴离子活性剂。

其它信息:

1.性状:本品为棕红色油状液体。

2.相对密度:1.05。

3.最大粘度:100 MPa·s。

4.溶解度:能溶于水和酒精。

脂肪醇醚硫酸钠 安全信息

海关代码:
2833400000

脂肪醇醚硫酸钠 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WB7499000
CHEMICAL NAME :
Sodium lauryl ether sulfate
CAS REGISTRY NUMBER :
9004-82-4
LAST UPDATED :
199806
DATA ITEMS CITED :
7

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
33NFA8 "Animal Models in Dermatology: Relevance to Human Dermatopharmacology and Dermatotoxicology," Maibach, H., ed., New York, Churchill Livingston, 1975 Volume(issue)/page/year: -,12,1975
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0534800
TYPE OF TEST :
Immersion
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
REFERENCE :
33NFA8 "Animal Models in Dermatology: Relevance to Human Dermatopharmacology and Dermatotoxicology," Maibach, H., ed., New York, Churchill Livingston, 1975 Volume(issue)/page/year: -.12,1975 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 2(5),1,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3231 No. of Facilities: 9263 (estimated) No. of Industries: 66 No. of Occupations: 56 No. of Employees: 131927 (estimated) No. of Female Employees: 58086 (estimated)

脂肪醇醚硫酸钠 MSDS


Section 1. Chemical Product and Company Identification
    Sodium Laureth Sulfate
    Common Name/
    Trade Name
    Sodium Laureth Sulfate

Section 3. Hazards Identification
    Potential Acute Health Effects Hazardous in case of skin contact (irritant), of eye contact (irritant). Slightly hazardous in case of skin contact
    (permeator), of ingestion, of inhalation.
    Potential Chronic Health        CARCINOGENIC EFFECTS: Not available.    
    Effects        MUTAGENIC EFFECTS: Not available.    
    TERATOGENIC EFFECTS: Not available.
    DEVELOPMENTAL TOXICITY: Not available.

Section 4. First Aid Measures
    Eye Contact        Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for    
    at least 15 minutes. Cold water may be used. Get medical attention.
    Skin Contact        In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient.    
    Remove contaminated clothing and shoes. Cold water may be used.Wash clothing before reuse. Thoroughly
    clean shoes before reuse. Get medical attention.
    Serious Skin Contact        Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek medical    
    attention.
    Inhalation        If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.    
    Get medical attention.
    Serious Inhalation        Not available.    
    Ingestion        Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an    
    unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if
    symptoms appear.
    Serious Ingestion        Not available.    

Section 5. Fire and Explosion Data
    Flammability of the Product May be combustible at high temperature.
    Auto-Ignition Temperature Not available.
    Flash Points        CLOSED CUP: 94°C (201.2°F). OPEN CUP: >100°C (212° F) (Cleveland.).    
    Flammable Limits        Not available.    
    Products of Combustion        Not available.    
    Fire Hazards in Presence of        Slightly flammable to flammable in presence of heat.    
    Various Substances        Non-flammable in presence of open flames and sparks, of shocks, of oxidizing materials, of reducing    
    materials, of combustible materials, of organic materials, of metals, of acids, of alkalis.
    Because of the large amount of water contained in the product, the product might be combustible only after
    partial or complete evaporation.
    Explosion Hazards in Presence Non-explosive in presence of open flames and sparks, of shocks.
    of Various Substances
    Fire Fighting Media        SMALL FIRE: Use DRY chemical powder.    
    and Instructions        LARGE FIRE: Use water spray, fog or foam. Do not use water jet.    
    Special Remarks on        Not available.    
    Fire Hazards
    Special Remarks on Explosion Not available.
    Hazards
    Sodium Laureth Sulfate

Section 6. Accidental Release Measures
    Small Spill        Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal    
    container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local
    and regional authority requirements.
    Large Spill        Absorb with an inert material and put the spilled material in an appropriate waste disposal. Finish cleaning by    
    spreading water on the contaminated surface and allow to evacuate through the sanitary system.

Section 7. Handling and Storage
    Precautions        Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not    
    ingest. Do not breathe gas/fumes/ vapor/spray. Wear suitable protective clothing. If ingested, seek medical
    advice immediately and show the container or the label. Avoid contact with skin and eyes. Keep away from
    incompatibles such as oxidizing agents.
    Keep container tightly closed. Keep container in a cool, well-ventilated area.
    Storage

Section 8. Exposure Controls/Personal Protection
    Engineering Controls        Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below    
    their respective threshold limit value. Ensure that eyewash stations and safety showers are proximal to the
    work-station location.
    Personal Protection        Splash goggles. Lab coat. Gloves. Respiratory protection is not necessary for normal handling. Good room    
    ventilation or use of local exhaust (fume hood) is sufficient. Use a vapor respirator under conditions where
    exposure to the substance is apparent (e.g. generation of high concentrations of mist or vapor, inadequate
    ventilation, development of respiratory tract irritation), and engineering controls are not feasible. Be sure to
    use an approved/certified respirator or equivalent.
    Personal Protection in Case of Splash goggles. Full suit. Boots. Gloves. Suggested protective clothing might not be sufficient; consult a
    a Large Spill        specialist BEFORE handling this product.    
    Exposure Limits        Not available.    

Section 9. Physical and Chemical Properties
    Physical state and appearance Liquid.        Odor        Not available.    
    Taste        Not available.    
    Molecular Weight        Not applicable.    
    Colorless to light yellow. Clear
    Color
    pH (1% soln/water)        Not available    
    Boiling Point        100°C (212°F)    
    Not available.
    Melting Point
    Critical Temperature        Not available.    
    1.03 (Water = 1)
    Specific Gravity
    Vapor Pressure        The highest known value is 2.3 kPa (@ 20°C) (Water) .    
    Vapor Density        The highest known value is 0.62 (Air = 1) (Water).    
    Volatility        Not available.    
    Odor Threshold        Not available.    
    Not available.
    Water/Oil Dist. Coeff.
    Ionicity (in Water)        Not available.    
    Dispersion Properties        See solubility in water.    
    Solubility        Soluble in cold water.    
    Soluble in alcohol and glycols
    Sodium Laureth Sulfate

Section 10. Stability and Reactivity Data
    The product is stable.
    Stability
    Instability Temperature        Not available.    
    Conditions of Instability        Excess heat, incompatible materials    
    Incompatibility with various        Reactive with oxidizing agents.    
    substances
    Not available.
    Corrosivity
    Special Remarks on        Not available.    
    Reactivity
    Not available.
    Special Remarks on
    Corrosivity
    Polymerization        Will not occur.    

Section 11. Toxicological Information
    Routes of Entry        Absorbed through skin. Eye contact. Ingestion.    
    Toxicity to Animals        Acute oral toxicity (LD50): 4848 - 5000 mg/kg (Rat) (Calculated value for the mixture).    
    Chronic Effects on Humans Not available.
    Other Toxic Effects on        Hazardous in case of skin contact (irritant), pf eye contact (irritant).    
    Humans        Slightly hazardous in case of skin contact (permeator), of ingestion, of inhalation.    
    Special Remarks on        Not available.    
    Toxicity to Animals
    Special Remarks on        This product contains <0.1% Formaldehyde which can cause cancer.    
    Chronic Effects on Humans        This product contains trace amounts of 1,4-Dioxane and Ethylene Oxide which can cause cancer.    
    This product may contain trace amounts of Ethylene oxide which may cause adverse reproductive effects and
    birth defects.
    Special Remarks on other        Acute Potential Health Effects:    
    Toxic Effects on Humans        Skin: Causes skin irritation. It may be absorbed through the skin.    
    Eyes: Causes eye irritation.
    Inhalation: Inhalation of mist or vapors may cause respiratory tract irritation.
    Ingestion: Low hazard. May cause digestive/gastrointestinal tract irritation.

Section 12. Ecological Information
    Ecotoxicity        Not available.    
    BOD5 and COD        Not available.    
    Products of Biodegradation        Possibly hazardous short term degradation products are not likely. However, long term degradation products    
    may arise.
    Toxicity of the Products        Not available.    
    of Biodegradation
    Special Remarks on the        Not available.    
    Products of Biodegradation
    Sodium Laureth Sulfate

Section 13. Disposal Considerations
    Waste Disposal        Waste must be disposed of in accordance with federal, state and local environmental    
    control regulations.

Section 14. Transport Information
    DOT Classification
    Not a DOT controlled material (United States).
    Not applicable.
    Identification
    Not applicable.
    Special Provisions for
    Transport
    DOT (Pictograms)

Section 15. Other Regulatory Information and Pictograms
    California prop. 65: This product contains the following ingredients for which the State of California has found
    Federal and State
    to cause cancer, birth defects or other reproductive harm, which would require a warning under the statute:
    Regulations
    Formaldehyde, 1,4-dioxane, Ethylene oxide
    California prop. 65: This product contains the following ingredients for which the State of California has found
    to cause reproductive harm (female) which would require a warning under the statute: Ethylene oxide
    California prop. 65: This product contains the following ingredients for which the State of California has found
    to cause cancer which would require a warning under the statute: Formaldehyde, 1,4-dioxane, Ethylene oxide
    TSCA 8(b) inventory: Water; Sodium Lauryl Ether Sulfate
    California        California prop. 65: This product contains the following ingredients for which the State of California has    
    found to cause cancer which would require a warning under the statute: Formaldehyde, 1,4-dioxane,
    Proposition 65
    Ethylene oxide
    Warnings
    California prop. 65: This product contains the following ingredients for which the State of California has
    found to cause birth defects which would require a warning under the statute: No products were found.
    Other Regulations        For CAS no. 9004-82-4:    
    EINECS: This product is not on the European Inventory of Existing Commercial Chemical Substances.
    Canada: Listed on Canadian Domestic Substance List (DSL).
    China: Listed on National Inventory.
    Japan: Listed on National Inventory (ENCS).
    Korea: Listed on National Inventory (KECI).
    Philippines: Listed on National Inventory (PICCS).
    Australia: Listed on AICS.
    WHMIS (Canada) CLASS D-2B: Material causing other toxic effects (TOXIC).
    Other Classifications
    DSCL (EEC)        R36/38- Irritating to eyes and skin.        S26- In case of contact with eyes, rinse    
    immediately with plenty of water and seek
    medical advice.
    S36/37- Wear suitable protective clothing and
    gloves.
    Health Hazard
    HMIS (U.S.A.)        2 National Fire Protection    
    0 Flammability
    0 Association (U.S.A.)
    Fire Hazard
    2 0 Reactivity
    Health
    Reactivity
    0
    Specific hazard
    Personal Protection
    j
    WHMIS (Canada)
    (Pictograms)
    Sodium Laureth Sulfate
    DSCL (Europe)
    (Pictograms)
    TDG (Canada)
    (Pictograms)
    ADR (Europe)
    (Pictograms)
    Protective Equipment
    Gloves.
    Lab coat.
    Wear appropriate respirator when
    ventilation is inadequate.


SECTION 16 - ADDITIONAL INFORMATION
N/A

脂肪醇醚硫酸钠 分子结构与计算化学数据

计算化学数据

1.疏水参数计算参考值(XlogP):无

2.氢键供体数量:0

3.氢键受体数量:5

4.可旋转化学键数量:15

5.互变异构体数量:无

6.拓扑分子极性表面积84

7.重原子数量:21

8.表面电荷:0

9.复杂度:290

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:2

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